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Cardiac Surgery

#AHA21 – M-A: Among patients with left main coronary disease, there was no statistically significant difference in 5-year all-cause death between percutaneous coronary intervention with drug-eluting stents vs. coronary artery bypass grafting.

16 Nov, 2021 | 08:31h | UTC

Percutaneous coronary intervention with drug-eluting stents versus coronary artery bypass grafting in left main coronary artery disease: an individual patient data meta-analysis – The Lancet (free registration required)

Commentary: No Mortality Difference Between PCI and CABG for Left Main PCI: Meta-analysis – TCTMD

 

Review and algorithm: Dysphagia aortica.

16 Nov, 2021 | 08:19h | UTC

Dysphagia aortica – European Surgery

 

#AHA21 – RCT: Concomitant tricuspid repair in patients undergoing surgery for degenerative mitral regurgitation reduced tricuspid regurgitation progression but increased the need for permanent pacemaker implantation.

14 Nov, 2021 | 20:00h | UTC

Concomitant Tricuspid Repair in Patients with Degenerative Mitral Regurgitation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

Tricuspid Repair During Mitral Surgery Slows Disease Progression at 2 Years – TCTMD

Cardiothoracic Surgical Trials Network: Concomitant Tricuspid Valve Repair + Mitral Valve Surgery vs. Mitral Valve Surgery Alone – CTCR-MVS – American College of Cardiology

CTCR-MVS: Concomitant Tricuspid Repair in Patients With MR – American College of Cardiology

 

#AHA21 – RCT: In asymptomatic patients with severe aortic stenosis, early surgery improved outcomes compared to conservative treatment.

14 Nov, 2021 | 20:01h | UTC

Aortic Valve ReplAcemenT versus Conservative Treatment in Asymptomatic SeveRe Aortic Stenosis: The AVATAR Trial – Circulation (free for a limited period)

News release: Surgery to replace heart valve beneficial even with no symptoms of severe aortic stenosis – American Heart Association

Commentaries:

AVATAR Supports Early SAVR in Asymptomatic Severe AS Patients – TCTMD

Aortic Valve ReplAcemenT versus Conservative Treatment in Asymptomatic SeveRe Aortic Stenosis – AVATAR – American College of Cardiology

Related study: #AHA19 – Randomized Trial: Early Surgery Improves Outcomes in Asymptomatic Patients with Very Severe Aortic Stenosis

 

Commentary on Twitter

 

#AHA21 – RCT: Among patients undergoing cardiac surgery, routine posterior left pericardiotomy can prevent postoperative atrial fibrillation.

14 Nov, 2021 | 19:53h | UTC

Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: an adaptive, single-centre, single-blind, randomised, controlled trial – The Lancet (free registration required)

Commentaries:

A short cut to prevent postoperative atrial fibrillation – The Lancet (free registration required)

Posterior Left Pericardiotomy for the Prevention of Postoperative Atrial Fibrillation After Cardiac Surgery – PALACS – American College of Cardiology

 

#AHA21 – [Not published Yet] A small, randomized study showed stopping ticagrelor only 2-3 days before bypass surgery may be safe.

14 Nov, 2021 | 19:56h | UTC

News release: Ticaglelor may be stopped Time from stopping blood thinner to bypass surgery may be shortened for select patients – American Heart Association

Commentary: RAPID CABG: No Penalty to Early Surgery for ACS After Stopping Ticagrelor – TCTMD

 

Lessons from a Superb Clinical Trial – commentary on a recent randomized trial testing left atrial appendage occlusion during cardiac surgery to prevent stroke.

9 Nov, 2021 | 01:08h | UTC

Lessons from a Superb Clinical Trial – by Dr. John Mandrola

Original Study: #ACC21 – Practice Changing RCT: In patients with atrial fibrillation (75% maintained on anticoagulation), left atrial appendage occlusion during cardiac surgery reduces the incidence of stroke and systemic embolism (4.8 vs. 7.0%) in the following years.

 

RCT: In patients with three-vessel coronary artery disease, an FFR–guided PCI strategy was NOT noninferior to coronary bypass surgery – The 1-year incidence of the composite primary end point (death, myocardial infarction, or stroke) was 7.3% in the FFR-guided PCI group and 5.2% in the CABG group.

5 Nov, 2021 | 09:49h | UTC

Fractional Flow Reserve–Guided PCI as Compared with Coronary Bypass Surgery – New England Journal of Medicine

Commentaries:

FAME 3: PCI Fails to Demonstrate Noninferiority to Surgery in Three-Vessel CAD – TCTMD

FAME 3: FFR-Guided PCI vs. CABG in Patients With Three-Vessel CAD – American College of Cardiology

Fractional Flow Reserve Versus Angiography for Multivessel Evaluation 3 – FAME 3 – American College of Cardiology

 

Commentary on Twitter

 

Guidelines for anesthesiologists on patient blood management in cardiac surgery.

17 Oct, 2021 | 21:22h | UTC

2021 Clinical Practice Guidelines for Anesthesiologists on Patient Blood Management in Cardiac Surgery – Journal of Cardiothoracic and Vascular Anesthesia

 

Commentary on Twitter

 

Varied extent of mitral annular disjunction among cases with different phenotypes of mitral valve prolapse.

7 Oct, 2021 | 10:12h | UTC

Varied Extent of Mitral Annular Disjunction Among Cases With Different Phenotypes of Mitral Valve Prolapse – JACC: Case Reports

 

Commentary on Twitter

 

Review: Coronary artery anomalies.

28 Sep, 2021 | 09:02h | UTC

Coronary Artery Anomalies – Circulation (free for a limited period)

 

Commentary on Twitter

 

#ESCCongress – 2021 ESC/EACTS Guidelines for the management of valvular heart disease – in the new guidelines, more patients are eligible for surgical and transcatheter interventions, based not only on symptoms but also on imaging criteria.

29 Aug, 2021 | 18:23h | UTC

2021 ESC/EACTS Guidelines for the management of valvular heart disease: Developed by the Task Force for the management of valvular heart disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) – European Heart Journal

News release: European valvular heart disease Guidelines published today – European Society of Cardiology

Summary: 2021 ESC/EACTS Valvular Heart Disease Guidelines: Key Points – American College of Cardiology

Commentary: Revamped Valve Disease Guideline: Europe Sees Nearly Eye to Eye With U.S. – MedPage Today (free registration required)

“In line with recent U.S. recommendations, the newest European guidelines favor a wider pool of patients eligible for surgical and transcatheter interventions for valvular heart disease.” (from MedPage Today)

 

Commentaries on Twitter

(thread – click for more)

 

Donor drug use is not associated with worse recipient survival in heart transplantation – “Increasing use of such donors may help alleviate the chronic donor shortage.”

30 Jul, 2021 | 11:39h | UTC

Intoxicated Donors and Heart Transplant Outcomes: Long-Term Safety – Circulation: Heart Failure

Commentary: Donor Drug Use Not Tied to Survival for Heart Transplant Recipients – HealthDay

Related study: National Trends in Heart Donor Usage Rates: Are We Efficiently Transplanting More Hearts? – Circulation: Heart Failure

 

ESC Consensus Document: Antithrombotic therapies in aortic and peripheral arterial diseases in 2021.

28 Jul, 2021 | 09:56h | UTC

Antithrombotic therapies in aortic and peripheral arterial diseases in 2021: a consensus document from the ESC working group on aorta and peripheral vascular diseases, the ESC working group on thrombosis, and the ESC working group on cardiovascular pharmacotherapy – European Heart Journal

Key Points to remember: ESC Consensus on Antithrombotic Therapies in Aortic and Peripheral Artery Diseases – American College of Cardiology

 

Commentary on Twitter

 

Expert consensus: Multimodality imaging of myocardial viability.

28 Jul, 2021 | 09:46h | UTC

Multimodality imaging of myocardial viability: an expert consensus document from the European Association of Cardiovascular Imaging (EACVI) – European Heart Journal – Cardiovascular Imaging

Related: Review | Myocardial perfusion and viability imaging in coronary artery disease: clinical value in diagnosis, prognosis and therapeutic guidance.

 

Commentary on Twitter

 

International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes.

26 Jul, 2021 | 02:27h | UTC

International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes – Annals of Thoracic Surgery

 

Commentary on Twitter

 

Position Statement on Endomyocardial Biopsy.

23 Jul, 2021 | 10:33h | UTC

Heart Failure Association, Heart Failure Society of America, and Japanese Heart Failure Society Position Statement on Endomyocardial Biopsy

 

Commentary on Twitter

 

WHO issues new recommendations on human genome editing for the advancement of public health.

13 Jul, 2021 | 09:42h | UTC

WHO issues new recommendations on human genome editing for the advancement of public health – World Health Organization

See reports:

Human genome editing: recommendations

Human genome editing: a framework for governance

Commentaries: New Global Recommendations for Human Genome Editing may Improve Use to Cure and Treat Diseases – Health Policy Watch AND WHO should lead on genome-editing policy, advisers say – Nature AND WHO Calls for Global Registry of Human Genome Editing – HealthDay AND Expert reaction to the WHO’s newly published recommendations and governance framework for human genome editing – Science Media Centre

 

Commentary on Twitter (thread – click for more)

 

AHA Scientific Statement: Mechanical Complications of Acute Myocardial Infarction.

16 Jun, 2021 | 08:21h | UTC

Mechanical Complications of Acute Myocardial Infarction: A Scientific Statement From the American Heart Association – Circulation

 

RCT: Low tidal volume ventilation is not superior to no ventilation during cardiopulmonary bypass in heart surgery.

8 Jun, 2021 | 09:16h | UTC

Low Tidal Volume Mechanical Ventilation Against No Ventilation During Cardiopulmonary Bypass in Heart Surgery (MECANO): A Randomized Controlled Trial – CHEST (link to abstract – $ for full-text)

 

#ACC21 – Practice Changing RCT: In patients with atrial fibrillation (75% maintained on anticoagulation), left atrial appendage occlusion during cardiac surgery reduces the incidence of stroke and systemic embolism (4.8 vs. 7.0%) in the following years.

17 May, 2021 | 08:33h | UTC

Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Simple surgery prevents strokes in heart patients – McMaster University AND Occluding the LAA During Surgery Lowers Stroke Risk: LAAOS III – TCTMD

Video: The Left Atrial Appendage Occlusion Study (LAAOS) III

 

Commentary on Twitter

 

AHA Statement: Prevention of Viridans Group Streptococcal Infective Endocarditis – Antibiotic prophylaxis for invasive dental procedures is suggested only for high-risk patients with the following conditions: 1) cardiac prosthetic valve; 2) previous infective endocarditis; 3) congenital heart disease; or 4) previous heart transplant

30 Apr, 2021 | 08:35h | UTC

Prevention of Viridans Group Streptococcal Infective Endocarditis: A Scientific Statement From the American Heart Association

News release: Good dental health may help prevent heart infection from mouth bacteria – American Heart Association

Top Things to Know: Prevention of Viridans Group Streptococcal Infective Endocarditis – American Heart Association

Slide set: Prevention of Viridans Group Streptococcal Infective Endocarditis

Commentaries: Commentary for Prevention of Viridans Group Streptococcal Infective Endocarditis – American Heart Association

 

Commentary on Twitter (thread – click for more)

 

Podcast: Congenital Heart Disease for the General Pediatrician

29 Apr, 2021 | 08:18h | UTC

#24: Congenital Heart Disease for the General Pediatrician – The Cribsiders

 

Opportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery

22 Apr, 2021 | 08:28h | UTC

Opportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery: A Review – JAMA Surgery (free for a limited period)

See also: Enhanced Recovery After Surgery (ERAS) Society Guidelines

 

Cohort Study: Effects of fluoroquinolones on outcomes of patients with aortic dissection or aneurysm

13 Apr, 2021 | 05:05h | UTC

Effects of Fluoroquinolones on Outcomes of Patients With Aortic Dissection or Aneurysm – Journal of the American College of Cardiology

Commentary: Fluoroquinolones Associated With Increased Risk of Aortic Dissection, Aneurysm – American College of Cardiology

Related: Another study suggests fluoroquinolone use may increase the risk of development of aortic aneurysms (study and commentaries) AND Link between fluoroquinolones, aorta problems may not be as strong as thought AND Study: Oral Fluoroquinolones and Risk of Mitral and Aortic Regurgitation AND FDA Warns About Increased Risk of Aortic Dissection and Ruptures of Aortic Aneurism with Fluoroquinolones AND Meta-analysis: Fluoroquinolones and the Risk of Aortopathy AND Study: Oral Fluoroquinolone and the Risk of Aortic Dissection AND Research: Fluoroquinolone use and risk of aortic aneurysm and dissection

 

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