Cardiac Surgery
M-A | Perioperative care bundles for the prevention of surgical-site infections.
2 Aug, 2022 | 12:30h | UTC
RCT | In patients at risk for antithrombin deficiency after cardiac surgery, preoperative antithrombin supplementation did not result in better outcomes.
2 Aug, 2022 | 11:39h | UTCA Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Preoperative Antithrombin Supplementation in Patients at Risk for Antithrombin Deficiency After Cardiac Surgery – Anesthesia & Analgesia (link to abstract – $ for full-text)
M-A | Negative-pressure wound therapy for prevention of sternal wound infection after adult cardiac surgery.
28 Jul, 2022 | 13:03h | UTC
RCT | Effect of high- vs. low-dose tranexamic acid infusion on need for red blood cell transfusion and adverse events in patients undergoing cardiac surgery.
27 Jul, 2022 | 12:21h | UTCEffect of High- vs Low-Dose Tranexamic Acid Infusion on Need for Red Blood Cell Transfusion and Adverse Events in Patients Undergoing Cardiac Surgery: The OPTIMAL Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
#OrigInvestigation: Among pts who underwent cardiac surgery w cardiopulmonary bypass, high-dose vs low-dose tranexamic acid infusion resulted in a modest, statistically significant reduction in the proportion of pts receiving allogeneic RBC transfusion https://t.co/Eb7SWc8U26
— JAMA (@JAMA_current) July 26, 2022
RCT | External support for saphenous vein grafts in coronary artery bypass surgery.
26 Jul, 2022 | 11:44h | UTCExternal Support for Saphenous Vein Grafts in Coronary Artery Bypass Surgery: A Randomized Clinical Trial – JAMA Cardiology (link to abstract – $ for full-text)
Commentary on Twitter
This RCT found that the 12-month difference in intimal hyperplasia area between supported and unsupported grafts did not achieve statistical significance, after accounting for early graft occlusions. https://t.co/Qrx3QsmdLc
— JAMA Cardiology (@JAMACardio) July 4, 2022
RCT | In patients undergoing cardiac surgery with cardiopulmonary bypass, using a 4% albumin solution for volume expansion did not reduce adverse events compared to ringer acetate.
21 Jul, 2022 | 13:32h | UTCEffect of 4% Albumin Solution vs Ringer Acetate on Major Adverse Events in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Albumin vs Crystalloid Fluid for Resuscitation in Cardiac Surgery: New Evidence and Arguments in the Timeless Debate – JAMA (free for a limited period)
Commentary: Trial does not support albumin as primer, volume replacement solution in CABG – Healio (free registration required)
Commentary on Twitter
#OriginalInvestigation: Clinical trial findings do not support the use of 4% albumin solution in cardiac surgery with cardiopulmonary bypass. @EeroJPesonen https://t.co/uyWQRdxfuJ pic.twitter.com/RJ5M9NBb9x
— JAMA (@JAMA_current) July 19, 2022
Review | Temporary mechanical circulatory support: devices, outcomes, and future directions.
14 Jul, 2022 | 12:23h | UTC
Cohort Study | Aneurysm growth, survival, and quality of life in untreated thoracic aortic aneurysms.
12 Jul, 2022 | 12:26h | UTCCommentary: Growth, Survival, Quality of Life in Untreated Thoracic Aortic Aneurysms – American College of Cardiology
Tricuspid regurgitation: recent advances in understanding pathophysiology, severity grading and outcome.
7 Jul, 2022 | 12:38h | UTC
Registry-based cohort study | Interventions in adults with repaired coarctation of the aorta.
7 Jul, 2022 | 12:29h | UTC
M-A: Patent ductus arteriosus stent vs. surgical aortopulmonary shunt for initial palliation of cyanotic congenital heart disease with ductal‐dependent pulmonary blood flow.
30 Jun, 2022 | 11:00h | UTC
RCT: Prothrombin complex concentrate vs. plasma for post–cardiopulmonary bypass coagulopathy and bleeding.
30 Jun, 2022 | 10:50h | UTCProthrombin Complex Concentrate vs Plasma for Post–Cardiopulmonary Bypass Coagulopathy and Bleeding: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Commentary on Twitter
In this RCT of cardiac surgical patients, there was no significant difference in postoperative bleeding among patients receiving prothrombin complex concentrates (PCCs) or plasma. Fewer patients with PCCs required intraoperative RBCs after treatment. https://t.co/vqtNX7hQxA
— JAMA Surgery (@JAMASurgery) June 29, 2022
RCT: Effect of nitric oxide via cardiopulmonary bypass on ventilator-free days in young children undergoing congenital heart disease surgery.
28 Jun, 2022 | 10:55h | UTCEffect of Nitric Oxide via Cardiopulmonary Bypass on Ventilator-Free Days in Young Children Undergoing Congenital Heart Disease Surgery: The NITRIC Randomized Clinical Trial – JAMA (free for a limited period)
News Release: Nitric oxide does not improve babies’ recovery after heart surgery – University of Zurich
Commentary on Twitter
In this randomized clinical trial, among infants undergoing heart surgery, delivery of nitric oxide into the cardiopulmonary bypass did not increase ventilator-free survival at 28 days. https://t.co/VJzBLPOP6U
— JAMA (@JAMA_current) June 27, 2022
RCT: Effectiveness and safety of early initiation of poststernotomy cardiac rehabilitation exercise training.
23 Jun, 2022 | 12:59h | UTCEffectiveness and Safety of Early Initiation of Poststernotomy Cardiac Rehabilitation Exercise Training: The SCAR Randomized Clinical Trial – JAMA Cardiology (free for a limited period)
Commentary on Twitter
RCT found starting exercise 2 weeks post-sternotomy was as effective as starting at 6 weeks. Clinicians and cardiac rehabilitation professionals can recommend starting exercise training as early as 2 weeks post-sternotomy. https://t.co/MpBhRmyfUh
— JAMA Cardiology (@JAMACardio) June 22, 2022
Cardiac xenotransplantation: challenges, evolution, and advances.
20 Jun, 2022 | 00:58h | UTCCommentary: Many Hurdles to Clear Before Cardiac Xenotransplantation Takes Off – TCTMD
Related:
In 1st, US surgeons transplant pig heart into human patient – Associated Press
Results of Two Cases of Pig-to-Human Kidney Xenotransplantation – New England Journal of Medicine (link to abstract – $ for full-text)
After a flurry of firsts, xenotransplantation is suddenly back in the spotlight – STAT
M-A: Acute or subacute, the optimal timing for uncomplicated Type B aortic dissection.
16 Jun, 2022 | 10:46h | UTC
Isolated coarctation of the aorta: current concepts and perspectives.
14 Jun, 2022 | 10:49h | UTC
Review: Anticoagulation management of post-cardiac surgery new-onset atrial fibrillation.
7 Jun, 2022 | 11:01h | UTC
Exploratory RCT suggests Cardiovascular Magnetic Resonance accurately diagnoses cardiac allograft rejection in the first year after transplantation.
6 Jun, 2022 | 10:56h | UTCNews Release: Virtual biopsy set to transform heart transplant care – Victor Chang Cardiac Research Institute
Commentary on Twitter
#OriginalResearch: In this #RCT, #CMR-based surveillance reliably graded cardiac allograft rejection compared to a biopsy-based strategy @vass_vassiliou #AHAJournals https://t.co/0kbpeXUtu1 pic.twitter.com/FwDGdJldHK
— Circulation (@CircAHA) June 2, 2022
Cardiac metastasis from solid cancers: a 35-year single-center autopsy study.
3 Jun, 2022 | 10:54h | UTC
Guidelines for clothing in the operating theatre.
30 May, 2022 | 11:52h | UTCGuidelines for clothing in the operating theatre, 2021 – Anaesthesia Critical Care & Pain Medicine
M-A: Timing of cardiac surgery during pregnancy.
30 May, 2022 | 10:43h | UTCTiming of cardiac surgery during pregnancy: a patient-level meta-analysis – European Heart Journal (link to abstract – $ for full-text)
Commentary: Timing of Cardiac Surgery During Pregnancy – American College of Cardiology
Commentary on Twitter
Timing of cardiac surgery during pregnancy: a patient-level meta-analysishttps://t.co/l1YwmJrABL#EHJ #CardioTwitter @escardio @ESC_Journals #metaanalysis pic.twitter.com/eW2rf7pDLI
— EHJ Editor-in-Chief (@ehj_ed) May 14, 2022
M-A: Surgical timing in patients with infective endocarditis and with intracranial hemorrhage.
27 May, 2022 | 11:25h | UTC
Commentary from the author on Twitter
Check out the results of our meta-analysis regarding operation timing in endocarditis patients with intracranial hemorrhage.
An interesting highlight is the evident immortal-time bias present in most studies. See more: https://t.co/6YskZPIXWB@HrisKirov @MahmDiab @ToDoenst pic.twitter.com/HvcbjTQAjT
— Tulio Caldonazo, MD (@TulioCaldonazo) May 17, 2022
Under a Creative Commons Attribution‐Noncommercial License
Top 100 most-cited articles on enhanced recovery after surgery.
24 May, 2022 | 10:38h | UTCSee also: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines
RCT: Effect of transcatheter aortic valve implantation vs. surgical aortic valve replacement on all-cause mortality in patients with aortic stenosis.
18 May, 2022 | 11:12h | UTCEffect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Treatment of Aortic Stenosis With Transcatheter Aortic Valve Implantation – JAMA (free for a limited period)
Commentary on Twitter
In this study, among patients aged 70 years or older with severe, symptomatic aortic stenosis and moderately increased operative risk, treatment with TAVI was noninferior to surgery with respect to all-cause mortality at 1 year. https://t.co/ORegyw1PKs
— JAMA (@JAMA_current) May 17, 2022