Invited Commentary: Angiotensin-II receptor blockade in Marfan syndrome – The Lancet (free)
Related Commentary on Twitter
NEW—Irbesartan is associated with a reduction in the rate of aortic dilatation in children and young adults with #Marfansyndrome and could reduce the incidence of aortic complications: finding from AIMS, double-blind, placebo-controlled randomised trial https://t.co/uVUWOC062A pic.twitter.com/FPiph5RcJu
— The Lancet (@TheLancet) December 11, 2019
Surgeons withdraw support for heart disease advice – BBC (free)
YouTube Video: European guidelines on heart disease under review – BBC Newsnight (free)
See also: EACTS responds to BBC Newsnight’s investigation on the EXCEL trial – European Association for Cardio-Thoracic Surgery (free)
Commentary: EACTS Pulls Out of Left Main Guidelines After BBC Bombshell Alleging EXCEL Trial Cover-up – TCTMD (free)
Related Commentary on Twitter
Wow! Super 🔥🔥🔥🔥 breaking story!
Reanalysis of EXCEL using Universal Definition of MI would have changed results substantially.
Taggart may be vindicated.
H/t @MedCrisis @drjohnm https://t.co/Yu7qKuiBdV
— Venk Murthy (@venkmurthy) December 9, 2019
Related: European guidelines on perioperative venous thromboembolism prophylaxis – European Journal of Anaesthesiology (comprehensive resource on the subject) AND American Society of Hematology 2018 Guidelines for Management of Venous Thromboembolism: Prophylaxis for Hospitalized and Nonhospitalized Medical Patients (free)
Results of the Fontan Udenafil Exercise Longitudinal (FUEL) Trial – Circulation (free for a limited period)
Commentaries: Teens with Heart Disease Improve Exercise Capacity in Large Clinical Trial – Children’s Hospital of Philadelphia (free) AND Pediatric drug trial finds benefit in teens with heart defect – NIH News Releases (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
Related Commentary on Twitter
FUEL Trial- udenafil did not improve peak VO2, but did positively impact measures of exercise performance in pts w/FONTAN @PHNresearch @nih_nhlbi @HeartCare4Kids @ChildrensPhila #CircAHA19 #AHA19 #AHAJournals https://t.co/Kmt9GFASZR pic.twitter.com/WV0NITTg7y
— Circulation (@CircAHA) November 17, 2019
Commentaries: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches – ISCHEMIA – American College of Cardiology (free) AND ISCHEMIA Trial Examines Invasive vs. Conservative Strategy in SIHD Patients – American College of Cardiology (free) AND ISCHEMIA: Invasive Strategy No Better Than Meds for CV Events – TCTMD (free) AND Surgery for Blocked Arteries Is Often Unwarranted, Researchers Find – The New York Times (free) AND ISCHEMIA Trial Finds No Evidence of Lower Cardiac Event Rates in Patients Treated with Heart Procedures, but Better Quality of Life – PR Newswire (free) AND Big study casts doubt on need for many heart procedures – Associated Press (free) AND Stents no better than drugs for many heart patients: U.S. study – Reuters (free) AND Stents, bypass surgery show no benefit in heart disease mortality rates among stable patients – Stanford Medicine (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
Early Surgery or Conservative Care for Asymptomatic Aortic Stenosis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: RECOVERY Finds Early Surgery Beneficial For Asymptomatic Severe AS Patients – American College of Cardiology (free) AND Randomized Comparison of Early Surgery Versus Conventional Treatment in Very Severe Aortic Stenosis – RECOVERY – American College of Cardiology (free) AND Early Surgery Beats a Conservative Approach in Asymptomatic AS: RECOVERY – TCTMD (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
Related Commentary on Twitter
At a median of 6 years of follow-up, operative mortality or CV death occurred less frequently in asymptomatic patients with very severe aortic stenosis who received early valve replacement surgery than in those conservatively managed. #AHA19 https://t.co/hcQeoRqseJ
— NEJM (@NEJM) November 16, 2019
Effect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery: The FIBRES Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Should Fibrinogen Concentrate Replace Cryoprecipitate in Cardiac Surgery? (free for a limited period)
Original Article: Enhanced Recovery After Surgery (ERAS) Guidelines for Perioperative Care in Cardiac Surgery (free guideline and commentary)
Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Meta-Analysis of TAVR vs. SAVR in Low-Risk Patients – American College of Cardiology (free) AND TAVR Survival Surpasses SAVR in Low-Risk Patients: Meta-analysis – Medscape (free registration required)
“The one clear unknown that everyone points to is valve durability” (form Medscape)
“longer follow-up regarding valve degeneration will be needed to confirm TAVR as the preferred treatment for low-risk patients with severe AS.” (from American College of Cardiology)
Complete vs. Staged Repair of Tetralogy of Fallot in Neonates – American College of Cardiology (free)
Original Study: 2-Year Outcomes After Complete or Staged Procedure for Tetralogy of Fallot in Neonates – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the multicentre randomised controlled SYNTAX trial – The Lancet (link to abstract – $ for full-text)
Commentary: Bypass surgery and coronary stenting yield comparable 10-year survival – European Society of Cardiology (free)
Related Meta-Analysis: Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease (link to abstract) AND Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Left Main Coronary Artery Stenosis (free)
Related Commentary on Twitter
SYNTAX extended survival: 10yr all cause death PCI vs CABG:
❤️no significant difference in all cause death (24%CABG/27%PCI)
❤️CABG better than PCI for 3VD (21%CABG/28%PCI)
❤️no significant difference in LMS diseaseImpressive 94% FU.https://t.co/X4g9WgTBXI#ESCCongress pic.twitter.com/M7halGNnsv
— Sarah Hudson (@sarahhudsonuk) September 2, 2019
Surgery Does Not Improve Survival in Patients With Isolated Severe Tricuspid Regurgitation – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Surgery for Severe Tricuspid Regurgitation – American College of Cardiology (free)
Related Commentary on Twitter
In patients with isolated severe tricuspid regurgitation, surgery is not associated with improved survival compared with medical therapy alone. https://t.co/mfEzSMfHzh #JACC pic.twitter.com/10xwdCKaqt
— JACC Journals (@JACCJournals) August 12, 2019
Off-Pump Versus On-Pump Bypass Surgery for Left Main Coronary Artery Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Off- vs. On-Pump Surgery for Left Main Disease – American College of Cardiology (free) Higher Mortality With Off-Pump CABG: EXCEL Analysis – TCTMD (free)
Related Study: Five-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass (link to abstract and commentaries)
Related Commentary on Twitter
Among patients with left main disease treated with #cvCABG, off-pump surgery is associated with an increased risk of 3-year all-cause death compared to on-pump surgery. https://t.co/mPoMqJcRq2 #JACC pic.twitter.com/eBIXhUvlX2
— JACC Journals (@JACCJournals) August 8, 2019
News Release: More people born with a single lower heart chamber survive, but face challenges in quality and length of life (free)
Top Ten Things to Know: Evaluation and Management of the Child and Adult With Fontan Circulation (free)
Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Cardiac MRI Safely Reduces Invasive Tx for Stable Angina – MedPage Today (free registration required)
Safety of a Restrictive versus Liberal Approach to Red Blood Cell Transfusion on the Outcome of AKI in Patients Undergoing Cardiac Surgery: A Randomized Clinical Trial – Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentary: Restrictive Approach to Blood Cell Transfusions Safe for Heart Surgery Patients – American Society of Nephrology (free)
Related: Effects of restrictive red blood cell transfusion on the prognoses of adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials – Critical Care (free) AND Research: Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery (free study and commentaries) AND Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial – JAMA (free)
Adenosine Deaminase Diagnostic Testing in Pericardial Fluid – JAMA (free for a limited period)
Management of Congenital Heart Disease: State of the Art – Children (free articles)
Part I—ACYANOTIC Heart Defects
Part II—Cyanotic Heart Defects
“The efficacy and safety of NOACs as thromboprophylaxis for AF and VHD are similar to those of warfarin.”
Guidelines for Perioperative Care in Cardiac Surgery: Enhanced Recovery After Surgery Society Recommendations – JAMA Surgery (free for a limited period)
Invited Commentary: The Enhanced Recovery After Surgery in Cardiac Surgery Revolution – JAMA Surgery (free)
Related: Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)
Related Commentary on Twitter
Our Guidelines are out! Look for the 1st comprehensive #ERASCardiac statement to facilitate optimal Perioperative care of the #CardiacSurgery patient. Multiple sessions providing this content at #AATS2019 @JAMASurgery @AATSHQ https://t.co/78WEYDw6IP
— ERAS-CS (@ERASCardiac) May 4, 2019
The association between vegetation size and surgical treatment on 6-month mortality in left-sided infective endocarditis – European Heart Journal (link to abstract – $ for full-text)
Commentary: Early Surgery and Mortality Among Patients with IE and Large Vegetation – American College of Cardiology (free)
Effect of an Incentive Spirometer Patient Reminder After Coronary Artery Bypass Grafting: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Invited Commentary: Benefits of Incentive Spirometry: Still More Work to Do – JAMA Surgery (free)
Simple intervention leading to improved outcomes, but confirmatory studies are required (see invited commentary).
Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Hepatitis C-infected hearts and lungs safely transplanted – Brigham and Women’s Hospital (free) AND Hepatitis C Not A Barrier For Organ Transplantation, Study Finds – NPR (free) AND Hepatitis C-infected hearts and lungs can be safely transplanted, study says, opening way to more donors – STAT (free)
Related: Study: Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients (link to abstract and commentaries)
Summary: Epidural analgesia for heart surgery with or without the heart lung machine in adults – Cochrane Library (free)
“Compared with systemic analgesia, epidural analgesia may reduce the risk of myocardial infarction, respiratory depression, and atrial fibrillation / atrial flutter, as well as the duration of tracheal intubation and pain, in adults undergoing cardiac surgery.”
Bilateral versus Single Internal-Thoracic-Artery Grafts at 10 Years – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Single vs. Bilateral Internal Thoracic Artery Grafting – American College of Cardiology (free) AND Randomized Trial Comparing Bilateral with Single Internal-Thoracic-Artery Grafting for CABG Shows No Significant Difference in All-Cause Mortality – Cardiology Now (free) AND CABG: Death at 10 Years Similar With Bilateral or Single Internal Thoracic Artery Grafting – Cardiology Advisor (free)
Incidence, Predictors, and Outcomes of In-Hospital Percutaneous Coronary Intervention Following Coronary Artery Bypass Grafting – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Unplanned PCI After CABG – American College of Cardiology (free)
Related Commentary on Twitter
#PCI in post-CABG patients may mean higher morbidity and mortality: https://t.co/bRMWCKIZEM #JACC #cvCABG pic.twitter.com/LoRw1orZpb
— JACC Journals (@JACCJournals) February 4, 2019
Thoracic Aortic Aneurysms: Pearls and Pitfalls – emDocs (free)
Related: Clinical Cases Referring to Diagnosis and Management of Patients with Thoracic Aortic Pathologies Involving the Aortic Arch (free guideline and clinical cases)
Related Review: Cardiac Screening of Young Athletes: a Practical Approach to Sudden Cardiac Death Prevention (free)
Related Position Statement: Recommendations for Participation in Competitive Sports of Athletes with Arterial Hypertension (free)
Related Research: Sudden Cardiac Arrest during Participation in Competitive Sports (link to abstract and commentaries)
Long-term Survival following Multivessel Revascularization in Patients with Diabetes (FREEDOM Follow-On Study) – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Long-term FREEDOM: At Nearly 8 years, CABG Maintains Mortality Benefit Over PCI – TCTMD (free) AND FREEDOM Follow-On Study Findings Further Support CABG Over PCI in DM Patients With CAD – American College of Cardiology (free) AND AHA: CABG Still Better for Multivessel Disease in Diabetes – MedPage Today (free registration required)
Atrial septal defects – Journal of Thoracic Disease (comprehensive review – free articles)
Commentaries: Study IDs predictors of mortality in asymptomatic aortic stenosis – Cardiovascular Business (free) AND Silent Aortic Stenosis Outcomes Good With Close Surveillance – MedPage Today (free registration required)
Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis – New England Journal of Medicine (free for a limited period)
Commentaries: Partial Oral Treatment of Endocarditis – POET – American College of Cardiology (free) AND New treatment can halve hospital stays for some patients with heart infection – ESC Press Releases (free)
Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery – New England Journal of Medicine (free for a limited period)
“In moderate-to-high-risk patients undergoing cardiac surgery, six-month outcomes show that a restrictive red-cell transfusion strategy is noninferior to a liberal strategy” (via @NEJM see Tweet with Visual Abstract)
2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease (free PDF)
News Release: Societies Release Updated Guideline for Treating Adult Congenital Heart Disease Patients (free)
Key Points to Remember: 2018 AHA/ACC Guideline for Adults With Congenital Heart Disease – American College of Cardiology (free)
Association of Surgical Left Atrial Appendage Occlusion With Subsequent Stroke and Mortality Among Patients Undergoing Cardiac Surgery – JAMA (link to abstract – $ for full-text)
Commentary: Heart surgery: To have or not to have…your left atrial appendage closed – Mayo Clinic, via ScienceDaily (free) AND LAA Closure Tied to Better Heart Surgery Outcomes – MedPage Today (free registration required)
Perspective by Dr. Eugene Braunwald: Aortic Stenosis: Then and Now – Circulation (free for a limited period)
Hybrid Coronary Revascularization in Selected Patients With Multivessel Disease: 5-Year Clinical Outcomes of the Prospective Randomized Pilot Study – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)
Commentaries: Hybrid Revascularization: 5-Year Outcomes – American College of Cardiology (free)
Preoperative 6-Minute Walk Distance Is Associated With Postoperative Cognitive Dysfunction – The Annals of Thoracic Surgery (link to abstract – $ for full-text)
Commentaries: 6-minute walk test predicts cognitive problems after heart surgery – Cardiovascular Business (free) AND Simple walking test helps predict risk for cognitive issues after heart surgery – Elservier, via EurekAlert (free)
Advances in critical care management of patients undergoing cardiac surgery – Intensive Care Medicine (free for a limited period)
Source: Critical Care Reviews Newsletter
Radial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery – New England Journal of Medicine (free for a limited period)
Commentaries: More Data Show Benefits of Multiple Arterial Over Saphenous-Vein Grafting in CABG: Meta-analysis – TCTMD (free) AND Radial Artery or Saphenous Vein Grafts in CABG – American College of Cardiology (free)
Effect of Ticagrelor Plus Aspirin, Ticagrelor Alone, or Aspirin Alone on Saphenous Vein Graft Patency 1 Year After Coronary Artery Bypass Grafting: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Ticagrelor + Aspirin, Ticagrelor Alone, or Aspirin Alone on SVG Patency – American College of Cardiology, Latest in Cardiology (free)
““The major limitation of the DACAB trial is the selection of vein graft patency as the primary outcome”. Agree:we’re starting to understand CAD is a bit more complicated than an open duct (also for this reason, medical practice requires clinical outcomes)” (via @camialderighi see Tweet)
Review: Management of Left Main Coronary Artery Disease – Journal of the American Heart Association (free for a limited period)
Long-term Thromboembolic Risk in Patients With Postoperative Atrial Fibrillation After Coronary Artery Bypass Graft Surgery and Patients With Nonvalvular Atrial Fibrillation – JAMA Cardiology (free for a limited period)
Commentaries: Postoperative A-fib Not as Bad as Nonsurgical A-fib for Thromboembolism – TCTMD (free) AND Fib after CABG linked to minimal long-term stroke risk – Cardiovascular Business (free)
Commentary with key points to remember: European Position Paper on Spontaneous Coronary Artery Dissection – American College of Cardiology, Latest in Cardiology (free)
Related position statement: Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association – Circulation (free)
Fluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study – The BMJ (free)
Related: Aortic Dissection and Aortic Aneurysms Associated with Fluoroquinolones: A Systematic Review and Meta-Analysis – American Journal of Medicine (free) AND Fluoroquinolones and collagen associated severe adverse events: a longitudinal cohort study – BMJ Open (free) AND Risk of Aortic Dissection and Aortic Aneurysm in Patients Taking Oral Fluoroquinolone – JAMA Internal Medicine (free)
Meta-analysis: Long-Term Outcomes of On- Versus Off-Pump Coronary Artery Bypass Grafting – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Long-Term Outcomes of On- vs. Off-Pump CABG – American College of Cardiology, Latest in Cardiology (free)
“Off pump CABG. probably best used in a limited set of patients…” (via @keaglemd see Tweet)
This meta-analysis of randomized trials showed CABG had a mortality benefit over PCI in patients with multivessel disease, particularly those with diabetes and higher coronary complexity. There was no mortality benefit in patients with left main disease.
Association of Vegetation Size With Embolic Risk in Patients With Infective Endocarditis: A Systematic Review and Meta-analysis – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Infective Endocarditis Vegetation Size vs. Embolic Risk – American College of Cardiology, Latest in Cardiology (free) AND Larger Endocarditis Vegetations More Likely to Embolize, Kill – MedPage Today (free registration required)
Short-Term Versus Long-Term Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation in Elderly Patients: A Meta-Analysis of Individual Participant Data From 6 Randomized Trials – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)
Commentary: Dual Antiplatelet Therapy Duration in Elderly Patients – American College of Cardiology, Latest in Cardiology (free)
Short-term Dual Antiplatelet Therapy was not associated with increased risk of ischemic events in elderly patients and was associated with a significant reduction in major bleeding.
New-Onset Atrial Fibrillation After PCI or CABG for Left Main Disease: The EXCEL Trial – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: One in Five CABG Patients Develop New-Onset Atrial Fibrillation: EXCEL – TCTMD (free) AND Post-operative AFib common in CABG, linked to future stroke, death – Cardiovascular Business (free)
Opinion: Heart Stents Are Useless for Most Stable Patients. They’re Still Widely Used – The New York Times (10 articles per month are free)
Transcatheter versus surgical aortic valve replacement in patients at low surgical risk: A meta-analysis of randomized trials and propensity score matched observational studies – Catheterization Cardiovascular Interventions (link to abstract – $ for full-text)
Commentary: Meta-Analysis Raises ‘Red Flag’ on TAVR in Low-Risk Patients – TCTMD (free)
“Data from six studies show that while short-term mortality is similar between TAVR and SAVR, more low-risk TAVR patients die by 2 years” (from TCTMD)
Commentaries: Largest Study to Date Supports Surgical LAA Closure in A-fib Patients – TCTMD (free) AND Thromboembolism Less Likely With LAA Closure Added to Cardiac Surgery – MedPage Today (free registration required)
Randomized trials are needed to confirm these interesting findings.
Percutaneous PFO Closure Tied to Lower Risk for Recurrent Stroke – Physician’s First Watch (free) AND Meta-Analyses Support Stroke Prevention With PFO Closure – MedPage Today (free registration required)
Original article 1: Device Closure Versus Medical Therapy Alone for Patent Foramen Ovale in Patients With Cryptogenic Stroke: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Original article 2: Percutaneous Closure Versus Medical Treatment in Stroke Patients With Patent Foramen Ovale: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Alternative drug may prevent atrial fibrillation following heart surgery – NIHR Signal (free)
Original article: Colchicine for primary prevention of atrial fibrillation after open-heart surgery: Systematic review and meta-analysis – International Journal of Cardiology (link to abstract – $ for full-text)
Safety of Magnetic Resonance Imaging in Patients with Cardiac Devices – The New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: MRI scan safe for most people with older pacemakers, defibrillators – Reuters (free) AND Even Thoracic MRI Safe for ‘Legacy’ ICDs, Pacemaker Systems: Large Cohort Study – Medscape (free registration required) AND MRIs safe with older pacemakers, study finds – MedicalXpress (free)
Top Ten Things to Know: Defining Quality in Cardiovascular Imaging (free PDF)
Commentary: “Quality” in Cardiovascular Imaging – Getting to the Heart of the Meaning (free)
“PCI is associated with a reduction in the risk of major cardiovascular outcomes at short-term follow-up in patients with LMCA stenosis; but at long term, MACCE rate is increased for PCI”
Commentaries: Newborn Screening Policies For CHD Associated With Lower Infant Deaths – American College of Cardiology, Latest in Cardiology (free) AND Infant CCHD deaths cut by 33% after mandatory pulse oximetry testing – Cardiovascular Business (free) AND Screening for Critical Congenital Heart Disease at Birth Saves Lives – CDC (free)
Related guideline: Canadian Cardiovascular Society/Canadian Pediatric Cardiology Association Position Statement on Pulse Oximetry Screening in Newborns to Enhance Detection of Critical Congenital Heart Disease (free)
“The European Atlas of Cardiology brings together data from 56 countries to demonstrate the prevalence and cost of cardiovascular disease, and the need to utilise resources more effectively” (RT @OUPMedicine see Tweet)
Commentaries: Neither Sodium Bicarbonate nor Oral Acetylcysteine Prevents Contrast-Induced Kidney Injury – Physician’s First Watch (free) AND PRESERVE: No Benefit from Sodium Bicarbonate, Acetylcysteine After Angiography – Medscape (free registration required)
Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery – New England Journal of Medicine (free)
Commentaries: TRICS III: Restrictive Red-Cell Transfusion Noninferior to Liberal Use in Cardiac Surgery – TCTMD (free) AHA: Restrictive Blood Transfusion OK for Select Patients – MedPage Today (free registration required)
Related article: Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial – JAMA (free)
Mechanical or Biologic Prostheses for Aortic-Valve and Mitral-Valve Replacement – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Mechanical heart valve often the safest choice – Stanford Medicine (free) AND Mechanical or Biologic Prostheses for Aortic-Valve and Mitral-Valve Replacement? – NEJM 360 Resident (free) AND Mechanical or Tissue Valve for AVR and MVR – American College of Cardiology, Latest in Cardiology (free) AND Mechanical Valves Show Mortality Benefit Over Biologic Valves – Medscape (free registration required) AND Heart valve replacement success may depend on age, valve type – Reuters (free)
European guidelines on perioperative venous thromboembolism prophylaxis (free PDF articles):
– Patients with preexisting coagulation disorders and after severe perioperative bleeding
– Cardiovascular and thoracic surgery
– Surgery in the obese patient
– Surgery during pregnancy and the immediate postpartum period
– Day surgery and fast-track surgery
– Chronic treatments with antiplatelet agents
– Aspirin
Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Small Trial Raises Big Concerns That PCI In Stable Angina Is Just A Placebo – Cardiobrief (free) AND Diving Deep Into The ORBITA Trial – Cardiobrief (free) AND ‘Unbelievable’: Heart Stents Fail to Ease Chest Pain – The New York Times (10 articles per month are free) AND ORBITA: PCI Offers No Symptom Improvement Over Sham Procedure – TCTMD (free)
Editorial: Back to the Future in Cardiogenic Shock — Initial PCI of the Culprit Lesion Only (free)
Commentaries: CULPRIT-SHOCK Disputes Benefit of Immediate Multivessel PCI in Patients With Cardiogenic Shock – TCTMD (free) AND CULPRIT-SHOCK: Culprit Lesion Only PCI Vs. Immediate Multivessel PCI in Cardiogenic Shock – American College of Cardiology, Latest in Cardiology (free)
Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a randomised study – The Lancet (link to abstract – $ for full-text)
Commentaries: Why Heart Surgery May be Better in the Afternoon – Scientific American (free) AND Afternoon heart surgery has lower risk of complications, study suggests – The Guardian (free) AND Aortic Valve Replacement: Afternoon Surgery Linked to Fewer Adverse Events – Physician’s First Watch (free)
Commentaries: Expert Consensus Decision Pathway for Management of Mitral Regurgitation – American College of Cardiology, Latest in Cardiology (free) AND ACC Recommends ‘Structured Approach’ to Mitral Regurgitation – MedPage Today (free registration required)
2017 Appropriate Use Criteria for the Treatment of Patients With Severe Aortic Stenosis (free)
Commentaries: 2017 AUC for Management of Severe Aortic Stenosis – American College of Cardiology, Latest in Cardiology (free) AND First Appropriate Use Criteria Issued for Severe Aortic Stenosis – Medpage Today (free registration required)
Older people with acute coronary syndromes may benefit from routine invasive therapy – NIHR Signal (free)
Original article: Revascularisation compared with initial medical therapy for non-ST-elevation acute coronary syndromes in the elderly: a meta-analysis – Heart (link to abstract – $ for full-text)
Commentaries: Study: Triple-Vessel CABG Strategy Matters in the Long Run – MedPage Today (free registration required)
In patients with multivessel disease who are undergoing coronary artery bypass grafting, multiple arterial grafting (MAG) is associated with reduced mortality, repeated revascularization, myocardial infarction, and heart failure when compared with left internal thoracic artery (LITA) supplemented by saphenous vein grafts (LITA+SVG).
News release: Looking beyond the heart in adults with congenital heart disease (free)
Commentary: Think Outside the Heart: Noncardiac Complications and Considerations in the Adult Congenital Patient (free)
Top Ten Things to Know: Diagnosis and Management of Noncardiac Complications in Adults with Congenital Heart Disease (free PDF)
Predicting 30-Day Mortality for Patients With Acute Heart Failure in the Emergency Department: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Tool may help accurately predict 30-day mortality for emergency department patients with acute heart failure – 2 Minute Medicine (free) AND Simple tool accurately predicts 30-day mortality for patients with acute heart failure in the ER – MedicalXpress (free)
See Calculator: MEESSI-AHF RISK MODEL
Invited commentary: Coronary Computed Tomographic Angiography—The First Test for Evaluating Patients With Chest Pain? (free)
Commentary: Coronary CT Angiography vs. Stress Testing: Meta-Analysis Offers Mixed Results – Physician’s First Watch (free)
Coronary Computed Tomografic Angiography (CCTA) was associated with a very small reduction in the incidence of myocardial infarction (0.7% vs 1.1% = 0.4% absolute risk reduction), but without differences in death or cardiac hospitalization. Patients undergoing CCTA were significantly more likely to undergo invasive coronary angiography (11.7% vs 9.1%), revascularization (7.2% vs 4.5%) and were also more likely to receive a diagnosis of new CAD and to have initiated aspirin or statin therapy.
D-dimer to guide the intensity of anticoagulation in Chinese patients after mechanical heart valve replacement: a randomized controlled trial – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)
Source: ACP Journal Wise ($)
Interventions for treating tuberculous pericarditis – Cochrane Library (free)
News release: Treatment for tuberculosis infection of the membrane around the heart (free)
“For HIV-negative patients, corticosteroids may reduce death. For HIV-positive patients not on antiretroviral drugs, corticosteroids may reduce constriction. For HIV-positive patients with good antiretroviral drug viral suppression, clinicians may consider the results from HIV-negative patients more relevant”.
Association of Guideline Adherence for Serial Evaluations With Survival and Adverse Clinical Events in Patients With Asymptomatic Severe Aortic Stenosis – JAMA Cardiology (link to abstract – $ for full-text)
Commentaries: Serial Echos Valuable in Patients with Asymptomatic Severe Aortic Stenosis – Physician’s First Watch (free) AND Close Watch on Aortic Stenosis May Improve Outcomes – MedPage Today (free registration required)
Survival and Cardiovascular Outcomes of Patients With Secondary Mitral Regurgitation: A Systematic Review and Meta-analysis – JAMA Cardiology (link to abstract – $ for full-text)
Commentary: Even Mild Secondary Mitral Regurgitation Tied to Reduced Survival – MedPage Today (link to abstract – $ for full-text)
Original articles from the New England Journal of Medicine: Patent Foramen Ovale Closure or Antiplatelet Therapy for Cryptogenic Stroke (link to abstract – $ for full-text) AND Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke (link to abstract – $ for full-text) AND Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke (link to abstract – $ for full-text)
Palliative Care in Heart Failure: The PAL-HF Randomized, Controlled Clinical Trial – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Palliative Care Intervention Improves Quality of Life in Advanced Heart Failure Patients – American College of Cardiology, Latest in Cardiology (free) AND Palliative Care & CHF: PAL-HF trial – Pallimed (free)
Spontaneous Coronary Artery Dissection: Clinical Outcomes and Risk of Recurrence – Journal of The American College or Cardiology (link to abstract – $ for full-text)
Commentaries: Long-Term Outcomes of Spontaneous Coronary Artery Dissection – American College of Cardiology, Latest in Cardiology (free) AND Spontaneous Coronary Dissection Often Followed By MACE Long Term – MedPage Today (free registration required)
Beta-blockers were associated with less recurrence in this observational study.
Improving the Appropriate Use of Transthoracic Echocardiography: The Echo WISELY Trial – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Improving Echo Appropriateness: Audit and Feedback Intervention Works – TCTMD (free) AND Improving Appropriate Use of Transthoracic Echocardiography – American College of Cardiology, Latest in Cardiology (free)
Commentary with highlights from the document: Appropriate Use Criteria Published for Valvular Heart Disease Imaging Tests – American College of Cardiology, Latest in Cardiology (free)
Impact of Obesity on Intensive Care Unit Resource Utilization After Cardiac Operations – The Annals of Thoracic Surgery (link to abstract – $ for full-text)
Commentaries: Obese cardiac patients a drain on ICU resources – Cardiovascular Business (free) AND Obese Cardiac Surgery Patients a Burden on ICU Resources – TCTMD (free) AND Post–Cardiac Surgery ICU Usage Rises With Increasing Obesity – Medscape (free registration required)
Original article: Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (link to abstract – $ for full-text)
Underweight associated with highest mortality and costs after cardiac catheterization (free) (the results have not been published yet)
Commentaries: Underweight and Overlooked: Low BMI Patients May Be Highest-Risk Post-PCI – TCTMD (free) AND Underweight Patients Fare Worse After Heart Catheterization – Medscape (free registration required) AND ESC 2017: Underweight Is Associated With Highest Mortality and Costs After Cardiac Catheterization – PracticeUpdate (free registration required)
Closure of left atrial appendage during heart surgery protects the brain (LAACS) – ESC Press Releases (free) (the results have not been published yet)
Commentary: LAACS: LAA Closure May Protect Against Long-Term Cerebral Ischemic Events – American College of Cardiology, Latest in Cardiology (free)
The Prognostic Value of Coronary Artery Calcium in the PROMISE Study – Circulation (free PDF)
Editorial: Computed Tomography or Functional Stress Testing for the Prediction of Risk: Can I Have My Cake and Eat It? (free PDF)
Commentary: Prospective Multicenter Imaging Study for Evaluation of Chest Pain – PROMISE – American College of Cardiology, Latest in Cardiology (free)
2017 ESC/EACTS Guidelines for the management of valvular heart disease (free) (RT @rafavidalperez see Tweet)
Commentary: European Societies Issue New Valvular Heart Disease Guidelines, With Important Shifts – TCTMD (free)
See also: #ESCCongress Slides (free PPT file)
2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC) (free) (RT @rafavidalperez see Tweet)
Commentary: ESC Updates Guidelines for Treating STEMI Patients – TCTMD (free)
See also: #ESCCongress Slides (free PPT file)
CI Versus CABG in Patients With Type 1 Diabetes and Multivessel Disease – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Patients With Type 1 Diabetes and Multivessel Disease Have Greater Benefit From CABG Than PCI – American College of Cardiology, Latest in Cardiology (free) AND Revascularization in Patients With Type 1 Diabetes – American College of Cardiology, Latest in Cardiology (free)
CABG Appears Superior to PCI for Patients With Type 1 Diabetes, Multivessel Disease – TCTMD (free)
“The observational findings support existing recommendations favoring surgical revascularization in patients with diabetes” (from TCTMD).
Editorial: Rheumatic Heart Disease — An Iceberg in Tropical Waters (free) (RT @NEJM see Tweet with interesting table)
Quick Take Video Summary: What is the Global Burden of Rheumatic Heart Disease? (free)
Commentary: Death rates from rheumatic heart disease falling since 1990 – Institute for Health Metrics and Evaluation (free)
Five-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Off-Pump CABG Raises Long-Term Mortality Risk – Cardiobrief (free) AND Newer method of open-heart surgery carries more risks, study finds – STAT (free)
The 10-Year Prognostic Value of Zero and Minimal CAC – Journal of The American College of Cardiology (no abstract – $ for full text)
Commentary: Calcium in Arteries Influences Heart Attack Risk – UT Southwestern Medical Center, via NewsWise (free) AND Study: Calcium in arteries influences heart attack risk – UPI (free)
“Half of the participants had no calcium deposits in their arteries or a zero coronary artery calcium, or CAC, score, and had less than a 3 percent chance of a cardiovascular event over a 10-year period despite having other risk factors for heart disease and stroke such as type 2 diabetes, high blood pressure and high bad cholesterol levels” (from UPI)
Increasing Prevalence of Atrial Fibrillation and Permanent Atrial Arrhythmias in Congenital Heart Disease – Journal of The American College of Cardiology (link to abstract and infographic – $ for full-text)
Commentary: Atrial Fibrillation in Congenital Heart Disease – American College of Cardiology, Latest in Cardiology (free)
Review: The Future of Cardiovascular Magnetic Resonance Imaging – European Heart Journal (free)
Source: Medscape
Eliminating Creatine Kinase–Myocardial Band Testing in Suspected Acute Coronary Syndrome: A Value-Based Quality Improvement – JAMA Internal Medicine (free) (RT @EricTopol see Tweet)
Author interview: Eliminating Creatine Kinase–Myocardial Band Testing in Suspected ACS (free)
Commentaries: Eliminating CK-MB Testing in Suspected ACS – American College of Cardiology, Latest in Cardiology (free) AND Research review recommends eliminating widely ordered blood test for diagnosing heart attacks – Johns Hopkins Medicine, via Science Daily (free)
“Review is first publication from national consortium of academic medical centers working to eliminate unnecessary medical tests, treatments and procedures” (from Science Daily)