Cardiology (all articles)
RCT – 2ry Analysis | Elevated intracranial bleeding risk with low-dose aspirin in older adults
27 Jul, 2023 | 13:09h | UTCSee also: Visual Abstract
News Release: Low dose aspirin won’t help some older adults trying to avoid a stroke: study – Monash University
Commentary: Daily aspirin doesn’t prevent strokes in older, healthy people after all – The Conversation
Original Study: Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly
Related Guideline: USPSTF Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease.
Related Randomized Trials:
Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease
Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes
Related Meta-Analysis:
Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events
Related Opinions:
Aspirin for Primary Prevention: Is This the End of the Road?
Evidence evolving on aspirin as prevention – ACP Internist
#347 USPSTF Update: Aspirin for Primary Prevention of CVD – The Curbsiders
Scientific Statement | Addressing childhood obesity to reduce adult CV risk through lifestyle
27 Jul, 2023 | 13:03h | UTCNews Release: How to stop obese children having heart disease in adulthood – European Society of Cardiology
RCT | Pitavastatin effective in the primary prevention of cardiovascular disease in HIV-infected individuals
26 Jul, 2023 | 13:35h | UTCPitavastatin to Prevent Cardiovascular Disease in HIV Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
Pitavastatin lowers risk of cardiovascular events in people living with HIV – Aidsmap
Statins reduce cardiovascular risk in people living with HIV, new global study finds – STAT
Pitavastatin Cuts MACE in HIV-Infected Patients: REPRIEVE – TCTMD
Commentary on Twitter
Original Article: Pitavastatin to Prevent Cardiovascular Disease in HIV Infection https://t.co/HuR0Lt24N5
Editorial: HIV and Cardiovascular Disease — An Ounce of Prevention https://t.co/fsxCqrLKi0#IAS2023 pic.twitter.com/TCSQkJQNYa
— NEJM (@NEJM) July 24, 2023
ISCHEMIA Trial 2ry Analysis | Patients with CCD and daily/weekly angina seem to benefit most from complete revascularization
26 Jul, 2023 | 13:33h | UTCComplete Revascularization and Angina-Related Health Status in the ISCHEMIA Trial – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries:
Complete Revascularization and Angina-Related Health Status – American College of Cardiology
More Angina Relief With Complete Revascularization in Stable CAD: ISCHEMIA – TCTMD
Related/Original Articles:
ISCHEMIA Trial: Initial Invasive vs. Conservative Strategy for Stable Coronary Disease
ISCHEMIA Trial: Management of Coronary Disease in Patients with Advanced Kidney Disease
Perspective | What does it mean to discover a coronary blockage?
26 Jul, 2023 | 13:31h | UTCChapter 1: What Does it Mean to Discover a Coronary Blockage? – By Dr John Mandrola
Chapter 2: On the meaning of a coronary blockage – By Dr John Mandrola
M-A | P2Y12 monotherapy after 1-3 months DAPT safely reduces bleeding in PCI patients with CAD and CKD
26 Jul, 2023 | 13:18h | UTCRelated:
De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis – Nature Reviews Cardiology (if the link is paywalled, try this one)
Long-term Effects of P2Y12 Inhibitor Monotherapy After Percutaneous Coronary Intervention: 3-Year Follow-up of the SMART-CHOICE Randomized Clinical Trial – JAMA Cardiology (link to abstract – $ for full-text)
RCT | High-power radiofrequency improves AF ablation results vs. standard-power, but may increase asymptomatic cerebral emboli
26 Jul, 2023 | 13:16h | UTCA Randomized Trial of High vs Standard Power Radiofrequency Ablation for Pulmonary Vein Isolation: SHORT-AF – JACC: Clinical Electrophysiology (link to abstract – $ for full-text)
M-A | Vegetarian diets may modestly improve cardiometabolic profile in high-risk individuals
26 Jul, 2023 | 13:15h | UTCCommentary: M-A: Vegetarian diets may modestly improve cardiometabolic profile in high-risk individuals – HCP Live
Diagnostic management of acute pulmonary embolism: a prediction model based on a patient data meta-analysis
26 Jul, 2023 | 13:11h | UTCDiagnostic management of acute pulmonary embolism: a prediction model based on a patient data meta-analysis – European Heart Journal (free for a limited period)
Commentary on Twitter
Diagnostic management of acute pulmonary embolism: a prediction model based on a patient data meta-analysis https://t.co/9CbFpZzEWv @escardio #EHJ #ESCYoung @ehj_ed @rladeiraslopes pic.twitter.com/qqmAEoEpqe
— European Society of Cardiology Journals (@ESC_Journals) July 26, 2023
Cohort Study | Examining patient demographics, microbiology, and mortality in infectious endocarditis after TAVI
25 Jul, 2023 | 13:48h | UTC
Cohort Study | Association found between carpal tunnel syndrome and heart failure incidence
25 Jul, 2023 | 13:42h | UTCCommentary: Carpal Tunnel Syndrome Again Tied to Heart Failure: German Data – TCTMD
Consensus Paper | De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and PCI
24 Jul, 2023 | 13:08h | UTCDe-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis – Nature Reviews Cardiology (if the link is paywalled, try this one)
Consensus Paper | Lung ultrasound in acute and chronic heart failure
24 Jul, 2023 | 13:06h | UTC
Systematic Review | Insufficient evidence for ACEi/ARB’s impact on early non-diabetic CKD
24 Jul, 2023 | 12:56h | UTC
Global perspectives on heart disease rehabilitation and secondary prevention
24 Jul, 2023 | 12:45h | UTC
2023 AHA/ACC Guideline for chronic coronary disease – B-blockers downgraded in patients without recent MI or low ejection fraction
21 Jul, 2023 | 13:52h | UTCKey Perspectives: 2023 Multisociety Guideline for Managing Chronic Coronary Disease – American College of Cardiology
Top things to know: 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease – American Heart Association
News Releases:
Commentary: New Chronic Heart Disease Guidelines Update Roles of GDMT, Imaging, and Revascularization – TCTMD
Commentary on Twitter with key points (thread – click for more)
?2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients w/ Chronic Coronary Disease aims to provide recommendations for diagnostic evaluation, symptom relief, improvement in QoL & reduction of future #ASCVD-related events & #heartfailure in patients w/ CCD.
— American College of Cardiology (@ACCinTouch) July 20, 2023
Cohort Study | ‘Weekend Warrior’ exercise pattern is associated with similar CVD benefits to regular activity
21 Jul, 2023 | 13:46h | UTCAccelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease – JAMA (free for a limited period)
Commentaries:
RCT | Half-dose Tenecteplase + later PCI if indicated seems to be viable option in older individuals when timely PCI is unavailable
21 Jul, 2023 | 13:36h | UTCHalf-Dose Tenecteplase or Primary Percutaneous Coronary Intervention in Older Patients With ST-Segment–Elevation Myocardial Infarction in STREAM-2: A Randomized, Open-Label Trial – Circulation (link to abstract – $ for full-text)
Commentary on Twitter
In the #STREAMI-2 trial of older adults w/ early-presenting STEMI, half-dose tenecteplase w/ PCI if indicated comparable to primary PCI for ECG/angio endpoints and 30d clinical efficacy but w/ higher risk of ICH @Cardio_KULeuven @CVC_UAlberta @BaineyKevin https://t.co/zFE6C1U98n pic.twitter.com/noWWhJ6y9h
— Circulation (@CircAHA) July 18, 2023
Phase 1 Trial | Zilebesiran demonstrates potential as prolonged-action hypertension therapeutic
21 Jul, 2023 | 13:32h | UTCZilebesiran, an RNA Interference Therapeutic Agent for Hypertension – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Experimental Shot Given Every Six Months Controlled High Blood Pressure in Early Trial – HealthDay
Pooled Analysis | Post-CABG graft failure found in 33.7% of patients, strongly linked to cardiac events
20 Jul, 2023 | 11:03h | UTCGraft Failure After Coronary Artery Bypass Grafting and Its Association With Patient Characteristics and Clinical Events: A Pooled Individual Patient Data Analysis of Clinical Trials With Imaging Follow-Up – Circulation (free for a limited period)
Commentary on Twitter
#OriginalResearch: In this analysis pooling individual level data from randomized trails, graft failure occured in 34% of patients undergoing CABG and was associated w/ increased risk of adverse clinical events #AHAJournals @WCM_CTSurgery https://t.co/Vg7t56pg0x pic.twitter.com/gmseiefME0
— Circulation (@CircAHA) July 18, 2023
Self-measured blood pressure telemonitoring programs: a pragmatic how-to guide
19 Jul, 2023 | 14:33h | UTC
AHA Scientific Statement | Cardiopulmonary impact of electronic cigarettes and vaping products
18 Jul, 2023 | 13:56h | UTCNews Releases:
Top Things to Know: Cardiopulmonary Impact of Electronic Cigarettes and Vaping Products – American Heart Association
Commentary: Vaping’s Risks to CV Health Not Yet Fully Known: AHA – CIDRAP
Nationwide Cohort Study | Adolescent hypertension linked with increased stroke risk in young adulthood
18 Jul, 2023 | 13:49h | UTCCommentary: The Relationship Between Adolescent Hypertension and Stroke Risk After Age 40 Years – Neurology Advisor
Cohort study | High-risk patent foramen ovale associated with increased decompression illness in scuba divers
18 Jul, 2023 | 13:43h | UTCDecompression Illness in Divers With or Without Patent Foramen Ovale: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
News Release: SCUBA divers with PFO at higher risk for decompression illness than previously thought – American College of Physicians
Commentary on Twitter
A study of #ScubaDivers found presence of high-risk PFO was associated with increased risk of decompression illness. Authors recommend divers with PFO should consider not diving or adhering to more conservative protocol: https://t.co/5Glt9B8Xup pic.twitter.com/AYbrDxiL0p
— Annals of Int Med (@AnnalsofIM) July 11, 2023
Cohort Study | Applying machine learning to ECG may improve identification of occlusion MI in individuals with chest pain
18 Jul, 2023 | 13:32h | UTCNews Release: New AI tool beats standard approaches for detecting heart attacks – University of Pittsburgh