Review: Cost-Effectiveness of Cardiotoxicity Monitoring

22Aug
2017

Study: Particulate Matter Exposure and Stress Hormone Levels

22Aug
2017

Study: Gastrointestinal safety of celecoxib versus naproxen in patients with cardiothrombotic diseases and arthritis after upper gastrointestinal bleeding

22Aug
2017

Gastrointestinal safety of celecoxib versus naproxen in patients with cardiothrombotic diseases and arthritis after upper gastrointestinal bleeding (CONCERN): an industry-independent, double-blind, double-dummy, randomised trial – The Lancet (link to abstract – $ for full-text)

Source: ACP Journal Club

In this study, patients at high risk of both cardiovascular and gastrointestinal events who required concomitant aspirin and NSAID, celecoxib associated with a proton pump inhibitor led to less recurrent gastrointestinal bleeding when compared to naproxen associated with a proton pump inhibitor (5.6% vs 12.3%).

 

Study: Risk of Arterial Thromboembolism in Patients With Cancer

22Aug
2017

Guideline: Screening and Management of High Blood Pressure in Children and Adolescents

22Aug
2017

Study: Hypertensive Disorders in Pregnancy and the Risk of Subsequent Cardiovascular Disease

22Aug
2017

Study: Smoking Cessation Pharmacotherapy Among Smokers Hospitalized for Coronary Heart Disease

22Aug
2017

Study: association of obesity and metabolic health with coronary heart disease

21Aug
2017

Decompensated Heart Failure

17Aug
2017

Cardiac Toxicity Of Cancer Chemotherapy

17Aug
2017

Five-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass

16Aug
2017

Mitral valve prolapse and Marfan syndrome

16Aug
2017

Role of nutrition support in adult cardiac surgery

16Aug
2017

SGLT2 agents may reduce cardiovascular risk in diabetics

16Aug
2017

Relationship of Alcohol Consumption to All-Cause, Cardiovascular, and Cancer-Related Mortality

15Aug
2017

The 10-Year Prognostic Value of Zero and Minimal CAC

15Aug
2017

The 10-Year Prognostic Value of Zero and Minimal CAC – Journal of The American College of Cardiology (no abstract – $ for full text)

Commentary: Calcium in Arteries Influences Heart Attack Risk –  UT Southwestern Medical Center, via NewsWise (free) AND Study: Calcium in arteries influences heart attack risk – UPI (free)

“Half of the participants had no calcium deposits in their arteries or a zero coronary artery calcium, or CAC, score, and had less than a 3 percent chance of a cardiovascular event over a 10-year period despite having other risk factors for heart disease and stroke such as type 2 diabetes, high blood pressure and high bad cholesterol levels” (from UPI)

 

Increasing Prevalence of Atrial Fibrillation and Permanent Atrial Arrhythmias in Congenital Heart Disease

15Aug
2017

Blood pressure targets for hypertension in older adults

15Aug
2017

Blood pressure targets for hypertension in older adults – Cochrane Library (free)

Full review: Blood pressure targets for hypertension in older adults – Cochrane Library (link to abstract – $ for full-text)

Related guideline: Pharmacologic Treatment of Hypertension in Adults Aged 60 Years or Older to Higher Versus Lower Blood Pressure Targets: A Clinical Practice Guideline From ACP and AAFP (free)

“At the present time there is insufficient evidence to know whether a higher BP target (less than150 to 160/95 to 105 mmHg) or a lower BP target (less than 140/90 mmHg) is better for older adults with high BP”

 

Longer sleep is associated with lower BMI and favorable metabolic profiles

15Aug
2017

Pharma Phantasy: The $30 Billion PCSK9 Inhibitor Market

15Aug
2017

The effect of high-flow nasal cannula in reducing the mortality and the rate of endotracheal intubation

15Aug
2017

The Future of Cardiovascular Magnetic Resonance Imaging

15Aug
2017

Eliminating CK–MB Testing in Suspected Acute Coronary Syndrome

15Aug
2017

Midlife Vascular Risk Factors and Incident Dementia

14Aug
2017

Day-to-Day Blood Pressure Variability and Risk of Dementia

14Aug
2017

Effect of 0.5 mg versus 1 mg varenicline for smoking cessation

14Aug
2017

Effect of 0.5 mg versus 1 mg varenicline for smoking cessation: a randomized controlled trial – Addiction (link to abstract – $ for full-text)

“No difference in smoking cessation effectiveness between 1 mg and 0.5 mg twice daily varenicline” (46.5% vs 46.4%) (RT @JorgeMTamayo see Tweet)

 

Duration of Dual Antiplatelet Therapy in Patients with an Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

11Aug
2017

Aspirin Does Not Increase Heart Failure Events in Heart Failure Patients

11Aug
2017

Mechanical Thrombectomy Outcomes With and Without Intravenous Thrombolysis in Stroke Patients

11Aug
2017

Mechanical Thrombectomy Outcomes With and Without Intravenous Thrombolysis in Stroke Patients: A Meta-Analysis – Stroke (link to abstract – $ for full-text)

Commentary: Better outcomes seen in patients who received IV thrombolysis before thrombectomy – ACP Hospitalist (free)

“The results support current guideline recommendations to give intravenous thrombolysis to eligible patients even if they are being considered for mechanical thrombectomy, according to the meta-analysis authors” (from ACP)

 

Anticoagulation for stroke prevention in very elderly patients with atrial fibrillation

11Aug
2017

Left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation

11Aug
2017

Depression and risk of death following coronary artery disease diagnosis

10Aug
2017

Neuroprotective Diets Are Associated with Better Cognitive Function

10Aug
2017

Challenges in Treating Cardiovascular Disease: Restricting Sodium and Managing Hyperkalemia

10Aug
2017

Surgical Guidelines for Perioperative Management of Older Adults

10Aug
2017

Effects of CPAP and Mandibular Advancement Devices on Health-Related Quality of Life in OSA

10Aug
2017

Effects of CPAP and Mandibular Advancement Devices on Health-Related Quality of Life in OSA – Chest (free)

See also a recent study showing CPAP does not reduce cardiovascular events in our July 13th issue (see #2)

“CPAP is effective in improving health-related quality of life in OSA, and Mandibular Advancement Devices may be just as effective, but further RCTs comparing the two treatments are required”.

 

Effect of marijuana use on cardiovascular and cerebrovascular mortality

10Aug
2017

Association of Estimated Sodium Intake With Adverse Cardiac Structure and Function

9Aug
2017

How Low Is Too Low With Salt in Heart Failure?

9Aug
2017

Clinical management of hypercholesterolaemia in patients with acute coronary syndromes

9Aug
2017

Severe infections and subsequent delayed cardiovascular disease

9Aug
2017

Richard Lehman’s journal review, 7 August 2017

7Aug
2017

Richard Lehman’s journal review, 7 August 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals.

 

Optimal timing of an invasive strategy in patients with non-ST-elevation acute coronary syndrome

7Aug
2017

Optimal timing of an invasive strategy in patients with non-ST-elevation acute coronary syndrome: a meta-analysis of randomised trials – The Lancet (link to abstract – $ for full-text)

Commentary: Optimal Timing of an Invasive Strategy in NSTE-ACS Patients – American College of Cardiology, Latest in Cardiology (free)

An early invasive strategy does not reduce mortality compared with a delayed invasive strategy in most patients with NSTE-ACS, but seems to reduce mortality in high-risk patients.

 

Long-term follow-up of patients with pulmonary thromboembolism

7Aug
2017

Guideline: stroke prevention in atrial fibrillation

7Aug
2017

Modifiable Risk Factors for Incident Heart Failure in Atrial Fibrillation

5Aug
2017

Modifiable Risk Factors for Incident Heart Failure in Atrial Fibrillation – Journal of The American College of Cardiology (link to abstract – $ for full-text)

Commentary: Risk for Incident Heart Failure in Atrial Fibrillation – American College of Cardiology, Latest in Cardiology (free)

“Lose weight, treat hypertension & diabetes, stop smoking: That’s how we might prevent heart failure” (RT @JACCJournals see Tweet)

 

Association of Resistance Exercise With the Incidence of Metabolic Syndrome

5Aug
2017

Mechanical clot removal for stroke reduces disability at two years

3Aug
2017

Mechanical clot removal for stroke reduces disability at two years – NIHR Signal (free)

“Mechanical thrombectomy within six hours of stroke onset provides a sustained reduction of disability for patients” (RT @NIHR_DC see Tweet)

 

Quitting statins after stroke may raise risk of another stroke

3Aug
2017

Peri-operative myocardial injury and infarction in patients undergoing coronary artery bypass graft surgery

3Aug
2017

Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease

3Aug
2017

Resuscitation medicine – Singapore Guidelines

3Aug
2017

New Online Calculator: The Smart Risk Score

1Aug
2017

New Online Calculator: The Smart Risk Score – European Society of Cardiology (RT @JGrapsa see Tweet)

“The SMART Risk Score is a tool to estimate 10-year risk for recurrent vascular events in patients with manifest cardiovascular disease”

 

Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac Arrest

1Aug
2017

Metabolic syndrome induced by anticancer treatment in childhood cancer survivors

1Aug
2017

Chronic kidney disease in adults – NICE Quality Standard

28Jul
2017

The Toll of Exercise on the Heart

28Jul
2017

Transcatheter aortic valve implantation for aortic stenosis

28Jul
2017

Application of a Lifestyle-Based Tool to Estimate Premature Cardiovascular Disease Events in Young Adults

28Jul
2017

Percutaneous short-term active mechanical support devices in cardiogenic shock

28Jul
2017

Percutaneous short-term active mechanical support devices in cardiogenic shock: a systematic review and collaborative meta-analysis of randomized trials – European Heart Journal (link to abstract – $ for full-text))

Commentary with 10 key points to remember: Mechanical Support Devices in Cardiogenic Shock – American College of Cardiology, Latest in Cardiology (free)

“Based on contemporary evidence, it appears prudent to restrict the use of active percutaneous MCS to selected patients” (from Latest in Cardiology)

“Results of this collaborative meta-analysis do not support the unselected use of active MCS patients with CS complicating AMI” (from original article)

 

Long working hours as a risk factor for atrial fibrillation

28Jul
2017

Magnetic Resonance in Cardiac Amyloidosis

28Jul
2017

Magnetic Resonance in Transthyretin Cardiac Amyloidosis – Journal of The American College of Cardiology (free)

Commentary: Magnetic Resonance in Transthyretin Cardiac Amyloidosis – American College of Cardiology, Latest in Cardiology (free)

“This study adds to a rich body of literature supporting the use of CMR in patients with known or suspected amyloidosis” (from Latest in Cardiology)

 

Nutrition Advice Aimed at Children May Improve Parents’ Diets

27Jul
2017

Prosthetic Valve Endocarditis After Surgical Aortic Valve Replacement

27Jul
2017

Prosthetic Valve Endocarditis After Surgical Aortic Valve Replacement – Circulation (free)

Commentary: Fewer infections in mechanical heart valves – Karolinska Institutet (free)

In this large cohort with follow-up time of up to 18 years, the risk of endocarditis was about 50 per cent higher with a biological prosthesis than with a mechanical prosthesis.

 

 

Comparison of Stenting Versus Bypass Surgery According to the Completeness of Revascularization in Severe Coronary Artery Disease

27Jul
2017

Association of Statin Use With Risk of Back Disorder Diagnoses

27Jul
2017

Long-Term Outcomes and Prognostic Factors of Complications in Takayasu’s Arteritis

27Jul
2017

Diabetes-Related Cardiac Dysfunction

27Jul
2017

Consensus statement on ambulatory ECG and external cardiac monitoring/telemetry

27Jul
2017

Guidelines on prevention of cardiovascular disease in patients with diabetes

27Jul
2017

Early Orthostatic Hypotension and Orthostatic Intolerance

25Jul
2017

Association of History of Dizziness and Long-term Adverse Outcomes With Early vs Later Orthostatic Hypotension Assessment Times in Middle-aged Adults – JAMA Internal Medicine (free)

Invited commentary: Early Orthostatic Hypotension and Orthostatic Intolerance—More Than an Observation or Annoyance (free)

Practice Changing – Orthostatic hypotension within 1 min of standing (rather than at 3 minutes) has greater relation to falls, fracture, syncope, motor vehicle crash, and mortality.

 

Guideline: Approach to Syncope in the Pediatric Patient

25Jul
2017

Guidelines for the Surgical Treatment of Atrial Fibrillation

25Jul
2017

The Continued Search for Physiological Pacing: Where Are We Now?

25Jul
2017

Updates in Management of Hyperkalemia

25Jul
2017

Cardiocerebral and cardiopulmonary resuscitation – 2017 update

25Jul
2017

Recent advances in the treatment of venous thromboembolism in the era of the direct oral anticoagulants

25Jul
2017

Clinical Impact of Baseline RBBB in Patients Undergoing TARV

25Jul
2017

Clinical Impact of Baseline Right Bundle Branch Block in Patients Undergoing Transcatheter Aortic Valve Replacement – JACC: Cardiovascular Interventions (link to abstract – $ for full-text)

Commentary: RBBB in TAVR Recipients (free)

“Pre-existing RBBB was found in 10% of TAVR recipients and was associated with poorer clinical outcomes”

 

Inconsistent Guideline Recommendations for Cardiovascular Prevention

25Jul
2017

Early vs Later Orthostatic Hypotension Assessment Times

25Jul
2017

Association of History of Dizziness and Long-term Adverse Outcomes With Early vs Later Orthostatic Hypotension Assessment Times in Middle-aged Adults – JAMA Internal Medicine (free)

Invited commentary: Early Orthostatic Hypotension and Orthostatic Intolerance—More Than an Observation or Annoyance (free)

Practice Changing – Orthostatic hypotension within 1 min of standing (rather than at 3 minutes) has greater relation to falls, fracture, syncope, motor vehicle crash, and mortality.

 

Viewpoint: Treatment of Cholesterol in 2017

25Jul
2017

Long-term morbidity and mortality in patients without early complications after stroke or transient ischemic attack

25Jul
2017

Management of elderly patients with a non-ST-segment-elevation acute coronary syndrome

25Jul
2017

Prescription Smoking Cessation Medications After Myocardial Infarction Underused

25Jul
2017

Alcohol and cardiovascular disease in the geriatric population

25Jul
2017

European Society of Cardiology Clinical Practice Guidelines Summary Cards

25Jul
2017

Review: Organ dysfunction, injury and failure in acute heart failure

24Jul
2017

Effects of NOACs Versus Warfarin in Patients With AF and Valvular Heart Disease

24Jul
2017

Emerging Data Show E-Cigarettes May Pose Heart Risk

23Jul
2017

Acute Aortic Syndromes: Diagnosis and Management

23Jul
2017

Cardiovascular implantable electronic devices: a review of the dangers and difficulties in MR scanning and attempts to improve safety

23Jul
2017

Cognitive Impairment and Heart Failure

23Jul
2017

Reviews on thrombosis and hemostasis

23Jul
2017

Screening strategies for atrial fibrillation: a systematic review and cost-effectiveness analysis

23Jul
2017

Screening strategies for atrial fibrillation: a systematic review and cost-effectiveness analysis – Health Technology Assessment (free)

Source: ACP Journal Wise ($)

“A national screening programme for atrial fibrillation is likely to represent a cost-effective use of resources, with systematic opportunistic screening more likely to be cost-effective than systematic population screening”

 

Educational Attainment And Risk of Cardiovascular Disease

22Jul
2017

Review: How I treat recurrent venous thromboembolism in patients receiving anticoagulant therapy

22Jul
2017

Prognostic Implications of Moderate Aortic Stenosis in Patients With Left Ventricular Systolic Dysfunction

22Jul
2017

Prognostic Implications of Moderate Aortic Stenosis in Patients With Left Ventricular Systolic Dysfunction – Journal of The American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Moderate Aortic Stenosis and LV Systolic Dysfunction – American College of Cardiology, Latest in Cardiology (free) AND High Risk of Clinical Events With Moderate Aortic Stenosis Plus LVSD – Medscape (free registration required)

In this observational study, patients with concomitant moderate aortic stenosis and left ventricular dysfunction were at high risk for clinical events and death.

 

More Millennials Are Having Strokes

22Jul
2017

Diabetic cardiomyopathy: where we are and where we are going

21Jul
2017

Practical management of peripartum cardiomyopathy

21Jul
2017
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