Cardiology

Five-Year Outcomes after PCI or CABG for Left Main Coronary Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: EXCEL at 5 Years: PCI for Left Main CAD Still Noninferior to CABG – TCTMD (free) AND EXCEL: No Significant Outcome Differences in PCI vs CABG for Left Main Coronary Disease at Five Years – American College of Cardiology (free)

Related Meta-Analysis: All-cause mortality and major cardiovascular outcomes comparing percutaneous coronary angioplasty versus coronary artery bypass grafting in the treatment of unprotected left main stenosis: a meta-analysis of short-term and long-term randomised trials – OpenHeart (free) AND Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Left Main Coronary Artery Stenosis: A Systematic Review and Meta-analysis – JAMA Cardiology (free) AND Percutaneous Coronary Intervention Using Drug-Eluting Stents Versus Coronary Artery Bypass Grafting for Unprotected Left Main Coronary Artery Stenosis: A Meta-Analysis of Randomized Trials – Circulation: Cardiovascular Interventions (free) AND Percutaneous intervention versus coronary artery bypass graft surgery in left main coronary artery stenosis: a systematic review and meta-analysis – BMC Medicine (free) AND Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease: a pooled analysis of individual patient data – The Lancet (link to abstract – $ for full-text)

 

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Efficacy of Neurohormonal Therapies in Preventing Cardiotoxicity in Patients With Cancer Undergoing Chemotherapy – JACC CardioOncology (free)

 

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Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function – JAMA (free for a limited period)

Commentaries: Metformin Superior for Lowering CV Risk in Diabetics Who Progress to CKD – Renal & Urology News (free) AND Metformin Monotherapy Benefits Heart Even in Early CKD – MedPage Today (free registration required)

 

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Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Meta-Analysis of TAVR vs. SAVR in Low-Risk Patients – American College of Cardiology (free) AND TAVR Survival Surpasses SAVR in Low-Risk Patients: Meta-analysis – Medscape (free registration required)

“The one clear unknown that everyone points to is valve durability” (form Medscape)

“longer follow-up regarding valve degeneration will be needed to confirm TAVR as the preferred treatment for low-risk patients with severe AS.” (from American College of Cardiology)

 


How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) – European Heart Journal (free)

 

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The Task Force for the management of patients with supraventricular tachycardia of the European Society of Cardiology (ESC): Developed in collaboration with the Association for European Paediatric and Congenital Cardiology (AEPC) (free)

 

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Maximum-fixed energy shocks for cardioverting atrial fibrillation – European Heart Journal (free)

Commentary: Comparison of High vs. Escalating Shocks – CHESS – American College of Cardiology (free)

 

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Commentaries: Dapagliflozin in Patients With Heart Failure and Reduced Ejection Fraction – DAPA-HF – American College of Cardiology (free) Dapagliflozin reduces death and hospitalisation in patients with heart failure – European Society of Cardiology (free)

 

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Commentaries: HiSTORIC Trial Supports Single-Test Rule-Out of MI Using High-Sensitivity Troponin – TCTMD (free) AND Risk-Based Thresholds for hs-Troponin I Safely Speed MI Rule-Out – MedPage Today (free registration required) AND HISTORIC: Early Rule-Out Strategy Using High-Sensitivity Cardiac Troponin I Reduced Length of Stay, Hospital Readmissions in Suspected ACS Patients – American College of Cardiology (free)

Related Studies: Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome (free study and commentaries) AND Cohort Study: The Introduction of High-sensitive Troponins Had No Impact on Survival (free study and commentaries)

 

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Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: PARAGON-HF: Sacubitril-Valsartan in HFpEF Patients Did Not Result in Significantly Lower Rates of Hospitalizations, Death – American College of Cardiology (free)

 

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Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Prasugrel cuts ischaemic events in acute coronary syndrome patients – European Society of Cardiology (free) AND Prasugrel Bests Ticagrelor in ACS Patients Heading to PCI: ISAR-REACT 5 – TCTMD (free) AND Intracoronary Stenting and Antithrombotic Regimen 5 – ISAR-REACT 5 – American College of Cardiology (free)

 

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Lazarus in asystole: a case report of autoresuscitation after prolonged cardiac arrest – European Heart Journal Case Reports (free)

 

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Cardiac Amyloidosis: Updates in Imaging

27 Aug, 2019 | 00:21h | UTC

Review: Palliative Inotrope Therapy

27 Aug, 2019 | 00:16h | UTC

Early Experience With Transcatheter Mitral Valve Replacement: A Systematic Review – Journal of the American Heart Association (free)

“TMVR was a feasible, less invasive alternative for treating severe mitral regurgitation in patients with high or prohibitive surgical risk”

 


Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study – The Lancet (link to abstract – $ for full-text)

 

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Surgery Does Not Improve Survival in Patients With Isolated Severe Tricuspid Regurgitation – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentary: Surgery for Severe Tricuspid Regurgitation – American College of Cardiology (free)

 

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Off-Pump Versus On-Pump Bypass Surgery for Left Main Coronary Artery Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Off- vs. On-Pump Surgery for Left Main Disease – American College of Cardiology (free) Higher Mortality With Off-Pump CABG: EXCEL Analysis – TCTMD (free)

Related Study: Five-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass (link to abstract and commentaries)

 

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Association of Office and Ambulatory Blood Pressure With Mortality and Cardiovascular Outcomes – JAMA (free for a limited period)

Editorial: Effective Use of Ambulatory Blood Pressure Monitoring (free)

Commentaries: Blood pressure recording over 24 hours is the best predictor of heart and vascular disease – KU Leuven (free) AND Nighttime, 24-Hour BP Readings Have Strongest Link to Poor Outcomes – TCTMD (free)

 

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Perioperative Management of Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant – JAMA Internal Medicine (free for a limited period)

Commentary: Study Sheds Light on Stopping and Resuming DOACs in Afib Patients Undergoing Surgery – NEJM Journal Watch (free)

“The DOAC regimens were omitted for 1 day before a low–bleeding-risk procedure and 2 days before a high–bleeding-risk procedure. The DOAC regimens were resumed 1 day after a low–bleeding-risk procedure and 2 to 3 days after a high–bleeding-risk procedure.”

 

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Potential Medicare Savings From Generic Substitution and Therapeutic Interchange of ACE Inhibitors and Angiotensin-II-Receptor Blockers – JAMA Internal Medicine (free for a limited period)

“By maximizing generic substitution and therapeutic interchange, Medicare could have saved approximately $676 million (89.6%) in 2016 and 2017 of the total $754 million spent on these brand-name ACEIs and ARBs during those 2 years”.

 


Meta-Analysis of Oral Anticoagulant Monotherapy as an Antithrombotic Strategy in Patients With Stable Coronary Artery Disease and Nonvalvular Atrial Fibrillation – The American Journal of Cardiology (link to abstract – $ for full-text)

Source: EvidenceAlerts

 

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Consensus on Non-cardiac Chest Pain

1 Aug, 2019 | 08:52h | UTC

Digoxin Discontinuation and Outcomes in Patients With Heart Failure With Reduced Ejection Fraction – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Stopping digoxin after a heart failure exacerbation associated with risk of readmission – ACP Hospitalist (free) AND Digoxin Swings Toward Benefit in HFrEF, But Lack of Clarity Remains – Medscape (free registration required)

 

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