Off-Pump Versus On-Pump Bypass Surgery for Left Main Coronary Artery Disease – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Off- vs. On-Pump Surgery for Left Main Disease – American College of Cardiology (free) Higher Mortality With Off-Pump CABG: EXCEL Analysis – TCTMD (free)

Related Study: Five-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass (link to abstract and commentaries)


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Association of Office and Ambulatory Blood Pressure With Mortality and Cardiovascular Outcomes – JAMA (free for a limited period)

Editorial: Effective Use of Ambulatory Blood Pressure Monitoring (free)

Commentaries: Blood pressure recording over 24 hours is the best predictor of heart and vascular disease – KU Leuven (free) AND Nighttime, 24-Hour BP Readings Have Strongest Link to Poor Outcomes – TCTMD (free)


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Perioperative Management of Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant – JAMA Internal Medicine (free for a limited period)

Commentary: Study Sheds Light on Stopping and Resuming DOACs in Afib Patients Undergoing Surgery – NEJM Journal Watch (free)

“The DOAC regimens were omitted for 1 day before a low–bleeding-risk procedure and 2 days before a high–bleeding-risk procedure. The DOAC regimens were resumed 1 day after a low–bleeding-risk procedure and 2 to 3 days after a high–bleeding-risk procedure.”


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Potential Medicare Savings From Generic Substitution and Therapeutic Interchange of ACE Inhibitors and Angiotensin-II-Receptor Blockers – JAMA Internal Medicine (free for a limited period)

“By maximizing generic substitution and therapeutic interchange, Medicare could have saved approximately $676 million (89.6%) in 2016 and 2017 of the total $754 million spent on these brand-name ACEIs and ARBs during those 2 years”.


Meta-Analysis of Oral Anticoagulant Monotherapy as an Antithrombotic Strategy in Patients With Stable Coronary Artery Disease and Nonvalvular Atrial Fibrillation – The American Journal of Cardiology (link to abstract – $ for full-text)

Source: EvidenceAlerts


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Consensus on Non-cardiac Chest Pain

1 Aug, 2019 | 08:52h | UTC

Digoxin Discontinuation and Outcomes in Patients With Heart Failure With Reduced Ejection Fraction – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Stopping digoxin after a heart failure exacerbation associated with risk of readmission – ACP Hospitalist (free) AND Digoxin Swings Toward Benefit in HFrEF, But Lack of Clarity Remains – Medscape (free registration required)


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The prevention and management of sudden cardiac arrest in athletes – Canadian Medical Association Journal (free for a limited period)

Commentary: Sudden cardiac arrest in athletes: Prevention and management – Joule Inc. (free)


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Consensus Statement on Renal Denervation

14 Jul, 2019 | 19:00h | UTC

Systolic Blood Pressure and Risk of Valvular Heart Disease: A Mendelian Randomization Study – JAMA Cardiology (free link for a limited period)

“Lifetime exposure to elevated systolic BP appears to be associated with an increased risk of major valvular heart disease.”


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Use of Directly Observed Therapy to Assess Treatment Adherence in Patients With Apparent Treatment-Resistant Hypertension – JAMA Internal Medicine (free link for a limited period)

Commentaries: Directly Observed Therapy Effective for Treatment-Resistant Hypertension – Clinical Advisor (free) AND Think it’s treatment-resistant hypertension? Your eyes need to DOT (directly observe therapy) – Univadis (free registration required)


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Myocarditis in Athletes Is a Challenge: Diagnosis, Risk Stratification, and Uncertainties – JACC: Cardiovascular Imaging (link to abstract and algorithm – $ for full-text)

Useful open access algorithm for them managing of this challenging condition.


Vitamin D Supplementation and Cardiovascular Disease Risks in More Than 83 000 Individuals in 21 Randomized Clinical Trials: A Meta-analysis – JAMA Cardiology (free for a limited period)

Commentaries: The Demise of Vitamin D for Cardiovascular Prevention – JAMA Cardiology (free for a limited period) AND Does Vitamin D Supplementation Provide Cardiovascular Protection? – MPR (free)


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Safety and efficacy of aspirin for primary prevention of cancer: a meta-analysis of randomized controlled trials – Journal of Cancer Research and Clinical Oncology (free)

“Our study did not find any significant reductions in cancer-related mortality or cancer incidence when compared aspirin use with placebo or no aspirin.”


Diagnosis of obstructive coronary artery disease using computed tomography angiography in patients with stable chest pain depending on clinical probability and in clinically important subgroups: meta-analysis of individual patient data – The BMJ (free)


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Management of Congenital Heart Disease: State of the Art – Children (free articles)

Part I—ACYANOTIC Heart Defects

Part II—Cyanotic Heart Defects


Randomized Trial of Lisinopril Versus Carvedilol to Prevent Trastuzumab Cardiotoxicity in Patients With Breast Cancer – Journal of the American College of Cardiology (link to abstract – $ for full-text)

“In patients with HER2-positive breast cancer treated with trastuzumab, both lisinopril and carvedilol prevented cardiotoxicity in patients receiving anthracyclines.”


Association of Preterm Birth With Risk of Ischemic Heart Disease in Adulthood – JAMA Pediatrics (free for a limited period)

Editorial: Cardiovascular Risk in Adults Born Preterm: Time to Act (free for a limited period)

Commentary: Preemies and early arrivals have higher risk of heart disease as adults – Reuters (free)


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Deprescribing in Older Adults with Cardiovascular Disease – Journal of the American College of Cardiology (free for a limited period)

Related: Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)


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Comparison of the New Oral Anticoagulants and Warfarin in Patients with Atrial Fibrillation and Valvular Heart Disease: Systematic Review and Meta-Analysis – Drugs in R&D (free)

“The efficacy and safety of NOACs as thromboprophylaxis for AF and VHD are similar to those of warfarin.”


Decompensated congestive heart failure – treatment with levosimendan – Revista da Associação Brasileira de Medicina (free)

“In patients with dilated cardiomyopathy and ejection fraction < 30% (heart failure post-intervention or not), levosimendan does not reduce the risk of death.”


Guidelines for Perioperative Care in Cardiac Surgery: Enhanced Recovery After Surgery Society Recommendations – JAMA Surgery (free for a limited period)

Invited Commentary: The Enhanced Recovery After Surgery in Cardiac Surgery Revolution – JAMA Surgery (free)

Related: Enhanced Recovery After Surgery (ERAS) Society Guidelines (free articles)


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