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Review | Diagnosis and management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome

4 Aug, 2023 | 11:50h | UTC

Diagnosis and management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome – Cleveland Clinic Journal of Medicine

 

Review | Autoimmunity and postural orthostatic tachycardia syndrome: Implications in diagnosis and management

4 Aug, 2023 | 11:49h | UTC

Autoimmunity and postural orthostatic tachycardia syndrome: Implications in diagnosis and management – Cleveland Clinic Journal of Medicine

 

RCT – 2ry analysis | Use of NIPPV, NHFOV post-extubation outperforms NCPAP in neonates with severe respiratory failure or extremely preterm

4 Aug, 2023 | 11:48h | UTC

Effectiveness of Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation vs Noninvasive High-Frequency Oscillatory Ventilation as Support After Extubation of Neonates Born Extremely Preterm or With More Severe Respiratory Failure: A Secondary Analysis of a Randomized Clinical Trial – JAMA Network Open

Original Study: Noninvasive High-Frequency Oscillatory Ventilation vs Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation as Postextubation Support for Preterm Neonates in China: A Randomized Clinical Trial – JAMA Pediatrics

Related: Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation – Cochrane Library

 

Commentary on Twitter

 

Systematic Review | NIPPV potentially superior to NCPAP in reducing reintubation in extubated preterm neonates

4 Aug, 2023 | 11:46h | UTC

Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation – Cochrane Library

Related: M-A | Early NIPPV likely reduces the risk of respiratory failure and intubation in very preterm infants

 

M-A | Supine vs. nonsupine endotracheal intubation

4 Aug, 2023 | 11:45h | UTC

A Systematic Review and Meta-Analysis of Randomized Controlled Trials on Supine vs. Nonsupine Endotracheal Intubation – Critical Care Research and Practice

 

Review | Treatment of pediatric convulsive status epilepticus

4 Aug, 2023 | 11:42h | UTC

Treatment of pediatric convulsive status epilepticus – Frontiers in Neurology

 

M-A | Uncertain benefits of blood purification techniques in severe infection or sepsis

4 Aug, 2023 | 11:41h | UTC

Blood Purification for Adult Patients With Severe Infection or Sepsis/Septic Shock: A Network Meta-Analysis of Randomized Controlled Trials – Critical Care Medicine

 

ACP Guidance | Asymptomatic CRC screening advised from age 50 with fecal occult blood test every 2 years or colonoscopy every 10 years

3 Aug, 2023 | 13:48h | UTC

Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults: A Guidance Statement From the American College of Physicians – Annals of Internal Medicine

News Release: ACP issues updated guidance for colorectal cancer screening of asymptomatic adults – American College of Physicians

Commentary: Start screening for colorectal cancer at age 50 years, ACP suggests – ACP Internist

Summary for Patients: Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults – Annals of Internal Medicine

 

RCT | Recombinant human prourokinase demonstrates noninferiority to alteplase in acute ischemic stroke treatment

3 Aug, 2023 | 13:46h | UTC

Efficacy and Safety of Recombinant Human Prourokinase in the Treatment of Acute Ischemic Stroke Within 4.5 Hours of Stroke Onset: A Phase 3 Randomized Clinical Trial – JAMA Network Open

See also: Visual Abstract

 

RCT – 2ry analysis | Omega-3 supplementation linked to increased AF risk in post-MI patients

3 Aug, 2023 | 13:45h | UTC

Omega-3 fatty acid supplements and risk of atrial fibrillation and ‘micro-atrial fibrillation’: A secondary analysis from the OMEMI trial – Clinical Nutrition

Related:

M-A: Omega-3 fatty acids supplementation is associated with increased risk of atrial fibrillation.

M-A: Omega-3 fatty acids supplementation increases the risk of atrial fibrillation in patients with lipid disorders.

More data suggests no cardiovascular benefit from Omega-3 supplementation – secondary analysis of STRENGHT trial did not show an association between achieved Omega-3 fatty acid levels and major adverse cardiovascular outcomes in patients with high cardiovascular risk.

RCT: Omega-3 supplements do not reduce cardiovascular events in elderly patients after myocardial infarction

#AHA20 – Randomized trial: High-dose Omega-3 fatty acids did not reduce the risk of cardiac events in patients at high cardiovascular risk

Meta-Analysis of Randomized Trials: Little Benefit from Omega-3 Intake to Reduce Cardiovascular Disease Risk

 

Commentary from the author on Twitter (thread – click for more)

 

Global prevalence, years lived with disability, and trends in anemia burden by severity and cause, 1990–2021

3 Aug, 2023 | 13:43h | UTC

Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021 – The Lancet Haematology

News Release: New study reveals global anemia cases remain persistently high among women and children. Anemia rates decline for men – Institute for Health Metrics and Evaluation

 

Commentary on Twitter

 

Position Paper | Management of complicated diaphragmatic hernia in the acute setting

3 Aug, 2023 | 13:42h | UTC

Management of complicated diaphragmatic hernia in the acute setting: a WSES position paper – World Journal of Emergency Surgery

 

Position Paper | Perioperative antibiotic prophylaxis in skin surgery

3 Aug, 2023 | 13:39h | UTC

Perioperative antibiotic prophylaxis in skin surgery – Position paper of the Antibiotic Stewardship working group of the German Society for Dermatologic Surgery (DGDC) – Journal of the German Society of Dermatology

Part 1: Procedure- and patient-related risk factors

Part 2: Special indications and situations

 

Practice Guidance | Management of febrile neutropenia in immunocompetent children and youth

3 Aug, 2023 | 13:38h | UTC

Management of febrile neutropenia in immunocompetent children and youth – Canadian Paediatric Society

 

Systematic Review | Interstitial lung disease incidence at 11.7% in metastatic breast cancer patients using trastuzumab deruxtecan

3 Aug, 2023 | 13:36h | UTC

Incidence of interstitial lung disease and cardiotoxicity with trastuzumab deruxtecan in breast cancer patients: a systematic review and single-arm meta-analysis – ESMO Open

 

Cohort Study | Increased mortality rates in delirium tremens patients versus alcohol withdrawal or dependence

3 Aug, 2023 | 13:35h | UTC

Mortality and alcohol-related morbidity in patients with delirium tremens, alcohol withdrawal state or alcohol dependence in Norway: A register-based prospective cohort study – Addiction

 

Systematic Review | Necrotizing enterocolitis onset typically in third week for very preterm, low birthweight infants

3 Aug, 2023 | 13:33h | UTC

Age of onset of necrotising enterocolitis (NEC) and focal intestinal perforation (FIP) in very preterm and low birthweight infants: a systematic review – BMJ Open

 

M-A | Significant QOL and mental health improvements in caregivers via targeted interventions

3 Aug, 2023 | 13:28h | UTC

Interventions to improve outcomes for caregivers of patients with advanced cancer: a meta-analysis – JNCI: Journal of the National Cancer Institute

 

RCT | Risankizumab outperforms apremilast in moderate plaque psoriasis treatment

3 Aug, 2023 | 13:21h | UTC

Comparison of risankizumab and apremilast for the treatment of adult patients with moderate plaque psoriasis eligible for systemic therapy: results from a randomised, open-label, assessor-blinded phase IV (IMMpulse) study – British Journal of Dermatology

Commentary: Risankizumab Shown to be Superior to Apremilast in Treating Adults with Moderate Psoriasis – HCP Live

 

Study | Increasing alcohol-related mortality rates in US women, 1999-2020

3 Aug, 2023 | 13:20h | UTC

Trends in Alcohol-Related Deaths by Sex in the US, 1999-2020 – JAMA Network Open

Commentary: As alcohol-related deaths rise in the US, women are increasingly at risk, study shows – CNN

 

RCT | Ferric derisomaltose plus tranexamic acid may reduce blood transfusion risk by 50% in hip surgery

3 Aug, 2023 | 13:18h | UTC

Ferric derisomaltose and tranexamic acid, combined or alone, for reducing blood transfusion in patients with hip fracture (the HiFIT trial): a multicentre, 2 × 2 factorial, randomised, double-blind, controlled trial – The Lancet Haematology (link to abstract – $ for full-text)

 

RCT | No significant recurrence-free survival improvement with everolimus post-renal carcinoma surgery

3 Aug, 2023 | 13:17h | UTC

Adjuvant everolimus after surgery for renal cell carcinoma (EVEREST): a double-blind, placebo-controlled, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)

 

RCT | Early oral antibiotic switch in low-risk neutropenic sepsis shows mixed results

3 Aug, 2023 | 13:15h | UTC

Early switch to oral antibiotic therapy in patients with low risk neutropenic sepsis (EASI-SWITCH): A randomized non-inferiority trial – Clinical Microbiology and Infection

 

Registry Analysis | Takotsubo syndrome outcomes influenced by trigger type and patient characteristics

3 Aug, 2023 | 13:14h | UTC

Trigger‐Associated Clinical Implications and Outcomes in Takotsubo Syndrome: Results From the Multicenter GEIST Registry – Journal of American Heart Association

Commentary: Takotsubo Trigger Type Matters, With Physical Shocks Linked to Worse Outcomes – TCTMD

 

Study | Frequent soccer heading linked to cognitive impairment risk in retired players

3 Aug, 2023 | 13:12h | UTC

Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players – JAMA Network Open

Invited Commentary: Heading Frequency and Risk of Cognitive Impairment in Retired Male Professional Soccer Players – JAMA Network Open

Related:

Cohort study | Professional soccer players are at increased risk of Alzheimer’s disease and other dementias

Dementia risk in former professional footballers is related to player position and career length.

Study: Neurodegenerative Disease Mortality Increased Among Former Professional Soccer Players

 

Commentary on Twitter

 

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