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RCT | 0.01% atropine effective in reducing progression of myopia in children over 3 years

14 Jun, 2023 | 14:41h | UTC

Efficacy and Safety of 0.01% and 0.02% Atropine for the Treatment of Pediatric Myopia Progression Over 3 Years: A Randomized Clinical Trial – JAMA Ophthalmology

News Release: Eye drops slow nearsightedness progression in kids – Ohio State University

See also: Visual Abstract

Related:

RCT | Effect of repeated low-level red light on myopia prevention among children in China with premyopia

Efficacy of atropine for myopia control in children: A meta-analysis of randomized controlled trials – Journal of Family Medicine and Primary Care

Interventions for myopia control in children: a living systematic review and network meta‐analysis – Cochrane Library

RCT | Effect of low-concentration atropine eyedrops vs. placebo on myopia incidence in children

Crossover RCT | Spectacle lenses with highly aspherical lenslets for slowing myopia.

RCT | Effect of text messaging parents of school-aged children on outdoor time to control myopia.

RCT | Myopia control effect of repeated low-level red-light therapy in children.

RCT: Spectacle lenses with aspherical lenslets for myopia control vs. single-vision spectacle lenses.

Randomized trial: Effect of High add power, medium add power, or single-vision contact lenses on myopia progression in children

 


M-A | Postpartum care up to 1 year after pregnancy

14 Jun, 2023 | 14:39h | UTC

Postpartum Care up to 1 Year After Pregnancy: A Systematic Review and Meta-analysis – Agency for Healthcare Research and Quality

 


SR | Management of postpartum hypertensive disorders of pregnancy

14 Jun, 2023 | 14:37h | UTC

Management of Postpartum Hypertensive Disorders of Pregnancy – Agency for Healthcare Research and Quality

 


AAP standards for levels of neonatal care: II, III, and IV

14 Jun, 2023 | 14:35h | UTC

Standards for Levels of Neonatal Care: II, III, and IV – Pediatrics

News Release: AAP sets national standards for levels of neonatal care – AAP News

Commentary: National Standards Developed for Neonatal Care – HealthDay

 


AAP Technical Report | Dispensing medications at the hospital upon discharge from an emergency department

14 Jun, 2023 | 14:33h | UTC

Dispensing Medications at the Hospital Upon Discharge From an Emergency Department – Pediatrics

News Release: Report discusses ways to improve medication adherence after emergency visit – AAP News

Commentary: Dispensing Meds in Emergency Department Likely to Improve Adherence – HealthDay

 


M-A | Preoperative IV plus oral antibiotics reduce surgical site infections in elective colorectal surgery

14 Jun, 2023 | 14:31h | UTC

Mechanical bowel preparation and antibiotics in elective colorectal surgery: network meta-analysis – BJS Open

Related:

SR | Mechanical plus oral antibiotic bowel preparation may prevent complications in elective colorectal surgery

M-A: Strategies for antibiotic administration for bowel preparation among patients undergoing elective colorectal surgery – “the addition of oral antibiotics to intravenous antibiotics was associated with a reduction in the incidence of incisional surgical site infection by more than 50%”.

Meta-Analysis: Effects of Mechanical Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery

 

Commentary on Twitter

 


RCT | Talazoparib plus enzalutamide prolongs radiographic PFS vs. enzalutamide alone in metastatic castration-resistant prostate cancer

14 Jun, 2023 | 14:29h | UTC

Talazoparib plus enzalutamide in men with first-line metastatic castration-resistant prostate cancer (TALAPRO-2): a randomised, placebo-controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)

News Release: Talazoparib Plus Enzalutamide Improves rPFS Over Placebo Plus Enzalutamide in First-Line Treatment for Patients with mCRPC – ESMO

 


RCT | Second-line treatment with Axi-cel results in increased overall survival in large B-cell lymphoma

14 Jun, 2023 | 14:25h | UTC

Survival with Axicabtagene Ciloleucel in Large B-Cell Lymphoma – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: ASCO: Axi-cel significantly improves survival in patients with early relapsed or refractory large B-cell lymphoma – University of Texas MD Anderson Cancer Center

Commentary: Axicabtagene Ciloleucel Improves Overall Survival in Patients With Relapsed or Refractory Large B-Cell Lymphoma – The ASCO Post

 

Commentary on Twitter

 


Crossover RCT | THC and Cannabidiol demonstrate potential in Tourette syndrome tic management, despite cognitive impacts

14 Jun, 2023 | 14:27h | UTC

Tetrahydrocannabinol and Cannabidiol in Tourette Syndrome – NEJM Evidence

 


RCT | Cilta-cel shows superior progression-free survival over standard care in lenalidomide-refractory multiple myeloma

14 Jun, 2023 | 14:22h | UTC

Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Findings suggest cilta-cel may be key therapeutic option for patients with multiple myeloma after first relapse – Medical College of Wisconsin

Commentary: CARTITUDE-4 Shows Benefit With Ciltacabtagene Autoleucel in Lenalidomide-Refractory Multiple Myeloma – ASCO Daily News

 

Commentary on Twitter

 


Review | Acute graft-versus-host disease

14 Jun, 2023 | 14:20h | UTC

Acute graft-versus-host disease – Nature Reviews Disease Primers (if the link is paywalled, try this one)

 

Commentary on Twitter

 


RCT | Valbenazine outperforms placebo in alleviating chorea in Huntington’s disease

14 Jun, 2023 | 14:18h | UTC

Safety and efficacy of valbenazine for the treatment of chorea associated with Huntington’s disease (KINECT-HD): a phase 3, randomised, double-blind, placebo-controlled trial – The Lancet Neurology (link to abstract – $ for full-text)

News Release: Valbenazine improves chorea associated with Huntington’s disease – News Medical / University of Texas Health Science Center at Houston

 


ASCO Guideline Update | Human epidermal growth factor receptor 2 testing in breast cancer

14 Jun, 2023 | 14:15h | UTC

Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology–College of American Pathologists Guideline Update – Journal of Clinical Oncology

Commentary: ASCO-CAP Guideline Update Confirms Previous Recommendations for HER2 Testing in Breast Cancer – ASCO Daily News

 


Cluster RCT | Effects of implementation of a supervised walking program in veterans affairs hospitals

14 Jun, 2023 | 14:17h | UTC

Effects of Implementation of a Supervised Walking Program in Veterans Affairs Hospitals: A Stepped-Wedge, Cluster Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Supervised Walking Program Benefits Veterans Admitted to Hospital – Physician’s Weekly

 

Commentary on Twitter

 


Review | Basic, translational and clinical aspects of bronchiectasis in adults

14 Jun, 2023 | 14:13h | UTC

Basic, translational and clinical aspects of bronchiectasis in adults – European Respiratory Review

 

Commentary on Twitter

 


Guidance to best tools and practices for systematic reviews

14 Jun, 2023 | 14:12h | UTC

Guidance to best tools and practices for systematic reviews – Systematic Reviews

 


M-A | Oseltamivir fails to lower hospitalization risk in adult and adolescent influenza patients

13 Jun, 2023 | 14:12h | UTC

Evaluation of Oseltamivir Used to Prevent Hospitalization in Outpatients With Influenza: A Systematic Review and Meta-analysis – JAMA Internal Medicine

 

Commentary on Twitter

 


Viewpoint | Detecting selection bias in observational studies—when interventions work too fast

13 Jun, 2023 | 14:09h | UTC

Detecting Selection Bias in Observational Studies—When Interventions Work Too Fast – JAMA Internal Medicine (free for a limited period)

 

Commentary from the author on Twitter

 


Review | Wastewater monitoring can anchor global disease surveillance systems

13 Jun, 2023 | 14:07h | UTC

Wastewater monitoring can anchor global disease surveillance systems – The Lancet Global Health

Related:

Use of Wastewater for Mpox Outbreak Surveillance in California – New England Journal of Medicine

Wastewater network infrastructure in public health: Applications and learnings from the COVID-19 pandemic – PLOS Global Public Health

Opinion: Wastewater analysis can be a powerful public health tool—if it’s done sensibly.

CDC unveils its latest weapon in Covid-19 detection: wastewater.

CDC Report: Using Wastewater Surveillance Data to Support the COVID-19 Response — United States, 2020–2021.

Rapid, large-scale wastewater surveillance and automated reporting system enabled early detection of nearly 85% of COVID-19 cases on a University campus.

[Preprint] Wastewater genomic testing can effectively track COVID-19 variants of concern.

Human Waste Could Be The Next Big Weapon in Controlling COVID-19 – TIME

Next steps for wastewater testing to help end this pandemic — and prevent the next one – STAT

Sewage sleuths helped an Arizona town beat back Covid-19. For wastewater epidemiology, that’s just the start – STAT

The myriad ways sewage surveillance is helping fight COVID around the world – Nature

Testing sewage can give school districts, campuses and businesses a heads-up on the spread of COVID-19 – The Conversation

It’s time to begin a national wastewater testing program for Covid-19 – STAT

Coronavirus: Testing sewage an ‘easy win’ – BBC

Development of wastewater pooled surveillance of SARS-CoV-2 from congregate living settings – high sensitivity, but unable to distinguish new infectious cases from persistent convalescent shedding.

 


Saving time and money in biomedical publishing: the case for free-format submissions with minimal requirements

13 Jun, 2023 | 14:08h | UTC

Saving time and money in biomedical publishing: the case for free-format submissions with minimal requirements – BMC Medicine

Commentary: Revealed: the millions of dollars in time wasted making papers fit journal guidelines – Nature

 


Review | Diagnosis and management of depression in adolescents

13 Jun, 2023 | 14:05h | UTC

Diagnosis and management of depression in adolescents – Canadian Medical Association Journal

News Release: How to diagnose and manage depression in adolescents: A new review for clinicians – Canadian Medical Association Journal

 


AHA Scientific Statement | Contaminant metals as cardiovascular risk factors

13 Jun, 2023 | 14:04h | UTC

Contaminant metals as cardiovascular risk factors: a scientific statement from the American Heart Association – Journal of the American Heart Association

News Release: Chronic exposure to lead, cadmium and arsenic increases risk of cardiovascular disease – American Heart Association

Top Things to Know: Contaminant Metals as CV Risk Factors – American Heart Association

Commentary: Toxic Metals: The Poisons that are “Killing Us Softly” – American Heart Association

 

Commentary on Twitter

 


Consensus Statement | Three-dimensional transesophageal echocardiography

13 Jun, 2023 | 14:02h | UTC

Three-dimensional transoesophageal echocardiography: how to use and when to use—a clinical consensus statement from the European Association of Cardiovascular Imaging of the European Society of Cardiology – European Heart Journal – Cardiovascular Imaging

 


RCT | No change in delayed graft function with normothermic perfusion vs. cold storage in kidney transplants

13 Jun, 2023 | 14:00h | UTC

Normothermic machine perfusion versus static cold storage in donation after circulatory death kidney transplantation: a randomized controlled trial – Nature Medicine

 

Commentary on Twitter

 


Review | The cervical spine in tension type headache

13 Jun, 2023 | 13:58h | UTC

The cervical spine in tension type headache – Musculoskeletal Science and Practice

 

Commentary on Twitter

 


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