All Posts
Review | Antifungal stewardship interventions in patients with hematologic malignancies
16 Jun, 2023 | 13:47h | UTCAntifungal Stewardship Interventions in Patients with Hematologic Malignancies
M-A | Post-surgery interventions for hip fracture
16 Jun, 2023 | 13:45h | UTC
An integrative review on the acceptance of artificial intelligence among healthcare professionals in hospitals
16 Jun, 2023 | 13:46h | UTC
RCT | Prehospital use of tranexamic acid in severe trauma cases shows no superiority over placebo
15 Jun, 2023 | 15:16h | UTCPrehospital Tranexamic Acid for Severe Trauma – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Shining a new light on tranexamic acid for trauma care – Monash University
Commentary on Twitter
Late breaking at #CCR23: In the PATCH-Trauma trial involving adults with major trauma, treatment with tranexamic acid did not result in a greater number of patients surviving with a favorable functional outcome at 6 months than placebo. https://t.co/i8fu34ReCB pic.twitter.com/GEOtRphOBb
— NEJM (@NEJM) June 14, 2023
Consensus Statement | Concussion in sport
15 Jun, 2023 | 15:14h | UTC
Perspective | Observational studies must be reformed before the next pandemic
15 Jun, 2023 | 15:12h | UTCObservational studies must be reformed before the next pandemic – Nature Medicine
Evidence-based clinical practice guideline for deprescribing opioid analgesics
15 Jun, 2023 | 15:08h | UTC
RCT | Cannabis-based medicines show no significant relief for moderate-to-severe cancer pain
15 Jun, 2023 | 15:10h | UTCCannabis‐based medicines and medical cannabis for adults with cancer pain – Cochrane Library
Summary: Cannabis-based medicines for cancer pain – Cochrane Library
Cohort Study | Identification of an optimal threshold to define oliguria in critically ill patients
15 Jun, 2023 | 15:05h | UTC
Commentary on Twitter
Identification of an optimal threshold to define oliguria in critically ill patients
Read the full article: https://t.co/4msRdcWZYY@jlvincen @ISICEM #FOAMed #FOAMcc pic.twitter.com/5PfiXkE5FO
— Critical Care (@Crit_Care) June 9, 2023
RCT | No significant kidney outcome differences observed across glucose-lowering medications in T2D patients
15 Jun, 2023 | 15:02h | UTCComparative Effects of Glucose-Lowering Medications on Kidney Outcomes in Type 2 Diabetes: The GRADE Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
See also: Visual Abstract
Commentaries:
No differences found in effects of secondary diabetes drugs on kidney outcomes – ACP Diabetes
Do glucose-lowering medications have different effects on kidney outcomes? – News Medical
RCT | Dose-escalated simultaneous integrated boost radiotherapy in early breast cancer
15 Jun, 2023 | 15:04h | UTC
M-A | Similar death rates in left main disease patients treated with PCI or CABG, both in patients with and without ACS
15 Jun, 2023 | 14:59h | UTCPercutaneous Coronary Intervention vs Coronary Artery Bypass Graft Surgery for Left Main Disease in Patients With and Without Acute Coronary Syndromes: A Pooled Analysis of 4 Randomized Clinical Trials – JAMA Cardiology (link to abstract – $ for full-text)
Commentary: CABG and PCI Comparable in ACS Patients With Left Main CAD – TCTMD
RCT | Sublingual microcirculatory assessment fails to reduce 30-day mortality in shock patients
15 Jun, 2023 | 15:00h | UTC
Commentary on Twitter
Direct assessment of microcirculation in shock, prospective multicenter RCT
?knowledge of sublingual microcirculatory perfusion variables resulted in significantly more therapy adjustments
?these changes did not improve 30d survival
#FOAMcc @yourICM
?️ https://t.co/Mn5bAqjDtS pic.twitter.com/i3zPwomb0V— Intensive Care Medicine (@yourICM) June 6, 2023
SR | Quality improvement strategies for diabetes care: Effects on outcomes for adults living with diabetes
15 Jun, 2023 | 14:57h | UTC
M-A | Influencing factors of medication adherence in schizophrenic patients
15 Jun, 2023 | 14:56h | UTC
RCT | Nalbuphine reduces cough in idiopathic pulmonary fibrosis, despite adverse effects
15 Jun, 2023 | 14:55h | UTCNalbuphine Tablets for Cough in Patients with Idiopathic Pulmonary Fibrosis – NEJM Evidence
Cohort Study | Weight change and risk of obesity-related complications
15 Jun, 2023 | 14:53h | UTC
Commentary from the author on Twitter
Our paper showing association of weight loss on risk of developing 13 obesity-related complications
Weight loss benefit dependent on weight loss magnitude & initial BMI-weight gain associated with a similar risk ⬆️
4 patterns of association identifiedhttps://t.co/7iQCCsIJ3x pic.twitter.com/xVVLruS6Jg
— Prof Kamlesh Khunti (@kamleshkhunti) June 8, 2023
M-A | Comparing non-invasive tests, histology for predicting non-alcoholic fatty liver outcomes
15 Jun, 2023 | 14:50h | UTC
Review | Candidate biomarkers in psychiatric disorders
15 Jun, 2023 | 14:52h | UTCCandidate biomarkers in psychiatric disorders: state of the field – World Psychiatry
Review | Contribution of wastewater to antimicrobial resistance
15 Jun, 2023 | 14:49h | UTCRelated studies on surveillance of wastewater:
Use of Wastewater for Mpox Outbreak Surveillance in California – New England Journal of Medicine
Opinion: Wastewater analysis can be a powerful public health tool—if it’s done sensibly.
CDC unveils its latest weapon in Covid-19 detection: wastewater.
[Preprint] Wastewater genomic testing can effectively track COVID-19 variants of concern.
Human Waste Could Be The Next Big Weapon in Controlling COVID-19 – TIME
Next steps for wastewater testing to help end this pandemic — and prevent the next one – STAT
The myriad ways sewage surveillance is helping fight COVID around the world – Nature
It’s time to begin a national wastewater testing program for Covid-19 – STAT
Coronavirus: Testing sewage an ‘easy win’ – BBC
M-A | Biosimilar and reference biologics in rheumatoid arthritis show equivalent results
15 Jun, 2023 | 14:47h | UTCCommentary: Adalimumab, Etanercept, Infliximab Biosimilars Show Clinically Equivalence to Biologics in RA – HCP Live
Cohort Study | 63.1% of uncomplicated appendicitis in children successfully treated non-operatively at 1 year
15 Jun, 2023 | 14:45h | UTC
Commentary on Twitter
1y outcomes of CASCADE examining?treatment for uncomp?itis in kids ➡️overall success: 63.1%, 21.5% req?during hospitalisation, 10.4% recurrence @1y. Overall comp: 7.3%?vs. 1.3% in success Non?treatment. Thoughts?https://t.co/AuIgSKkU6w#SoMe4Surgery #some4peds #emgensurg pic.twitter.com/9mM5NFOEh1
— BJS Open (@BjsOpen) June 7, 2023
Imaging features of the postoperative spine: a guide to basic understanding of spine surgical procedures
15 Jun, 2023 | 14:43h | UTC
Review | Fluid therapy for critically ill adults with sepsis
14 Jun, 2023 | 14:51h | UTCFluid Therapy for Critically Ill Adults With Sepsis: A Review – JAMA (free for a limited period)
Audio clinical review: Fluid Therapy for Critically Ill Adults With Sepsis – JAMA
Perspective | Inside the nascent industry of AI-designed drugs
14 Jun, 2023 | 14:50h | UTCInside the nascent industry of AI-designed drugs – Nature (if the link is paywalled, try this one)