Open access


Mon, December 11 – 10 Stories of The Day!

11 Dec,2017


1 – ADA 2018 Standards of Medical Care in Diabetes – Diabetes Care (Free Supplement)

News Release: American Diabetes Association Releases 2018 Standards of Medical Care in Diabetes, with Notable New Recommendations for People with Cardiovascular Disease and Diabetes (free)

Summary of Revisions: Standards of Medical Care in Diabetes—2018 (free)

Commentaries: ADA 2018 Standards Address Diabetes Drugs With CV Benefit – Medscape (free registration required)


2 – Standards of Medical Care in Diabetes—2018 Abridged for Primary Care Providers – Diabetes Care (free PDF)

Commentary: ADA 2018 Abridged Standards of Medical Care in Diabetes: Update for Primary Care – Medscape (free registration required


3 – Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Pharmacomechanical Thrombolysis for Deep-Vein Thrombosis – NEJM Resident 360 (free) AND Pharmacomechanical Thrombolysis for DVT – American College of Cardiology, Latest in Cardiology (free)

Pharmacomechanical thrombolysis did not result in lower risk of post-thrombotic syndrome and was associated with higher risk of major bleeding.


4 – Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials – Intensive Care Medicine (free)

PPIs are the most effective agents in preventing CIB, but they may increase the risk of pneumonia”.


5 – Seven-Year Weight Trajectories and Health Outcomes in the Longitudinal Assessment of Bariatric Surgery (LABS) Study – JAMA Surgery (free)

Commentaries: We’re barely using the best tool we have to fight obesity – VOX (free) AND Gastric bypass patients sustain long-term weight loss, comorbidity reduction – Cardiovascular Business (free) AND Weight Loss After Bariatric Procedures Mostly Sustained Over Time – Medical Research (free)


6 – Bedtime Use of Technology and Associated Sleep Problems in Children – Global Pediatric Health (free)

Commentary: Screen time before bed linked with less sleep, higher BMIs in kids – Penn State, via ScienceDaily (free)


7 – Opinion: Does Cancer Screening Save More Lives Overall? Not Necessarily – WBUR (free) (via @HealthNewsRevu see Tweet)

Related systematic review: Does screening for disease save lives in asymptomatic adults? Systematic review of meta-analyses and randomized trials – International Journal of Epidemiology (free)

“We are not suggesting that cancer screening is useless. Our critique aims to show that screening tests are like any other medical intervention: there are benefits and harms.  And it’s why we support informed decision-making”.


8 – Themed Review: Comprehensive Care: Older People Living With Frailty in Hospitals  – NIHR Dissemination Centre (free download)


9 – Non-invasive cardiovascular imaging for evaluating subclinical target organ damage in hypertensive patients: A consensus paper from the European Association of Cardiovascular Imaging (EACVI), the European Society of Cardiology Council on Hypertension, and the European Society of Hypertension (ESH) – European Heart Journal Cardiovascular Imaging (free)


10 – The best and worst analogies for CRISPR, ranked – STAT (free)

Related: Simple guide to CRISPR, one of the biggest science stories of the decade – VOX (free)


Fri, December 8 – 10 Stories of The Day!

8 Dec,2017


1 – First Dementia Global Monitoring System Launched: Global Dementia Observatory (free resources)

News release: Dementia: number of people affected to triple in next 30 years – World Health Organization (free)


2 – The global burden of tuberculosis: results from the Global Burden of Disease Study 2015 – The Lancet Infectious Diseases (free)

Invited Commentary: Tuberculosis eradication: renewed commitment and global investment required (free)


3 – Practical Recommendations of the Obesity Management Task Force of the European Association for the Study of Obesity for the Post-Bariatric Surgery Medical Management (free)


4 – Systematic review of dietary trans-fat reduction interventions – Bulletin of The World Health Organization (free)

Related: Banning trans fats in New York prevented thousands of heart attacks, study finds – STAT News (free) AND The Worst Fat in the Food Supply – The New York Times (10 articles per month are free)


5 – Perioperative Myocardial Injury After Noncardiac Surgery: Incidence, Mortality, and Characterization – Circulation (free PDF)

Commentaries: Myocardial Injury After Noncardiac Surgery Linked With Higher 1-Year Mortality – TCTMD (free) AND Perioperative Myocardial Injury After Noncardiac Surgery – American College of Cardiology, Latest in Cardiology (free)


6 – Analysis: Transvaginal mesh failure: lessons for regulation of implantable devices – The BMJ (free)

Related commentaries: Women harmed because vaginal mesh regulation ‘not fit for purpose’ – The Guardian (free) AND Vaginal mesh operations for prolapse should be banned, watchdog to say – The Guardian (free)


7 – Case-control and Cohort studies: A brief overview – Students 4 Best Evidence (free)


8 – Blood Pressure Trajectories in the 20 Years Before Death – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Blood pressure declines 14 to 18 years before death – University of Connecticut, via ScienceDaily (free) AND Long, Slow Decline in BP Often Precedes Seniors’ Death – MedPage Today (free registration required)


9 – Understanding common misconceptions about p-values – The 20% Statistician (free)

Related review: Statistical tests, P values, confidence intervals, and power: a guide to misinterpretations – European Journal of Epidemiology (free)

Source: Nature Briefing Newsletter


10 – Low FODMAP diet may improve irritable bowel symptoms more than other diets – NIHR Signal (free)

Original article: Low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet improves symptoms in adults suffering from irritable bowel syndrome (IBS) compared to standard IBS diet: A meta-analysis of clinical studies – PLOS One (free)



Thu, December 7 – 10 Stories of The Day!

7 Dec,2017


1 – Book: Child and Adolescent Health and Development – Disease Control Priorities, 3rd Edition (free)

Press Release: DCP3 Publishes Latest Volume: Child and Adolescent Health and Development (free)

Key Messages from the Series: Disease Control Priorities 3rd edition – The Lancet (7 reviews – free registration required)

Other books in the series: Essential Surgery / Reproductive, Maternal, Newborn, and Child Health / Cancer / Mental, Neurological, and Substance Use Disorders / Injury Prevention and Environmental Health / Major Infectious DiseasesCardiovascular, respiratory, and related disorders / Disease Control Priorities (all free)

“Third edition of Disease Control Priorities launches today. A vast resource evaluating policy choices affecting the access, uptake & quality of interventions & delivery platforms to improve health in LMICs”. (RT @MRCTEG_LSHTM see Tweet)


2 – Contemporary Hormonal Contraception and the Risk of Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Even Low-Dose Contraceptives Slightly Increase Breast Cancer Risk – NPR (free) AND Study confirms higher breast cancer risk with hormone-based contraception – Reuters (free) AND Small risk of breast cancer seen with hormone contraceptives – Associated Press (free) All forms of hormonal contraception carry breast cancer risk, study finds – the Guardian (free) AND Birth Control Pills Still Linked to Breast Cancer, Study Finds – The New York Times (10 articles per month are free)


3 – Effectiveness of and overdiagnosis from mammography screening in the Netherlands: population based study – The BMJ (free)

Editorial: Breast cancer screening (free)

Commentaries: Breast cancer screening has ‘little impact’ on cancer deaths – OnMedica AND It’s Time to End Mammograms, Some Experts Say – TIME (free)

See more on the arguments for and against screening for breast cancer with mammography in our November 7th issue (see #4)


4 – Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Gene Therapy for Factor IX Deficiency (free)

Commentary: One-dose gene therapy produces clotting factor, safely stops bleeding in hemophilia B patients – MedicalXpress (free)


5 – Recovery after critical illness: putting the puzzle together—a consensus of 29 – Critical Care (free)


6 – Moral Choices for Today’s Physician – JAMA (free)


7 – Two nerve drugs are not suitable for treating long-term low back pain – NIHR Signal (free)

Original Article: Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials – PLOS One (free)

“Evidence supports NICE guidance not to use two nerve drugs (gabapentin and pregabalin) to treat long-term lower back pain”. (RT @NIHR_DC see Tweet)


8 – Oral Sex and Condom Use in a U.S. National Sample of Adolescents and Young Adults – Journal of Adolescent Health (link to abstract – $ for full-text)

Commentary: Kids aren’t protecting themselves against STDs during oral sex – Reuters (free)


9 – Respiratory and cardiovascular responses to walking down a traffic-polluted road compared with walking in a traffic-free area in participants aged 60 years and older with chronic lung or heart disease and age-matched healthy controls: a randomised, crossover study – The Lancet (free)

Commentaries: Walking to a pathway for cardiovascular effects of air pollution – The Lancet (free) AND Traffic fumes in city streets ‘largely wipe out exercise benefits for over-60s’ – The Guardian (free)


10 – Impact of London’s road traffic air and noise pollution on birth weight: retrospective population based cohort study – The BMJ (free)

Editorial: Traffic pollution is linked to poor pregnancy outcomes (free)

Commentary: Air pollution from London traffic is affecting the health of unborn babies – Imperial College London (free) AND Traffic pollution linked to low birth weight of unborn babies, study reveals – Medical News (free)


Wed, December 6 – 10 Stories of The Day!

6 Dec,2017


1 – Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Intensive weight loss can ‘reverse’ type 2 diabetes – OnMedica (free) AND Weight Management May Reverse T2D – MedPage Today (free registration required) AND Radical diet can reverse type 2 diabetes, new study shows – The Guardian (free)


2 – Modern contraceptive use, unmet need, and demand satisfied among women of reproductive age who are married or in a union in the focus countries of the Family Planning 2020 initiative: a systematic analysis using the Family Planning Estimation Tool – The Lancet (free)

Related Report: FP2020 – The Way Ahead (free)

Commentaries: Contraceptive use gaining momentum in world’s poorest countries – Reuters (free) AND FP2020 reports progress on family planning, but faces an uphill battle – Devex (free)


3 – Validation and diagnostic accuracy of predictive curves for age-associated longitudinal cognitive decline in older adults – Canadian Medical Association Journal (free)

Commentaries: New easy-to-use tool can help determine Alzheimer’s risk, similar to pediatric growth curves – CMAJ, via EurekAlert (free) AND Cognitive Decline Charts Could Help Flag Whether Patient Has Dementia – Physician’s First Watch (free)


4 – Readmissions After Revascularization Procedures for Peripheral Arterial Disease: A Nationwide Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Burden of Readmission High in PAD Patients Following Revascularization – TCTMD (free) AND 1 in 6 Patients Undergoing Peripheral Arterial Revascularization Readmitted Within 30 Days – Physician’s First Watch (free) AND 1 in 6 Readmitted After Peripheral Revascularization – MedPage Today (free registration required)


5 – It’s Gonna Get a Lot Easier to Break Science Journal Paywalls – Wired (Free) (via @EricTopol)


6 – Cherry-picking by trialists and meta-analysts can drive conclusions about intervention efficacy – Journal of Clinical Epidemiology (free)


7 – A Failure to Heal – The New York Times Magazine (10 articles per month are free) (RT @camialderighi see Tweet)


8 – Association of Clinician Denial of Patient Requests With Patient Satisfaction – JAMA Internal Medicine (free)

Commentaries: Clinician denial of certain patient requests linked with decreased satisfaction – 2 Minute Medicine (free) AND Denial of some patient requests, but not others, associated with decreased patient satisfaction, study finds – ACP Internist (free) AND Patient satisfaction surveys are worthless – Physician’s Weekly (free)


9 – Association of US State Implementation of Newborn Screening Policies for Critical Congenital Heart Disease With Early Infant Cardiac Deaths – JAMA (free)

Commentaries: Newborn Screening Policies For CHD Associated With Lower Infant Deaths – American College of Cardiology, Latest in Cardiology (free) AND Infant CCHD deaths cut by 33% after mandatory pulse oximetry testing – Cardiovascular Business (free) AND Screening for Critical Congenital Heart Disease at Birth Saves Lives – CDC (free)

Related guideline: Canadian Cardiovascular Society/Canadian Pediatric Cardiology Association Position Statement on Pulse Oximetry Screening in Newborns to Enhance Detection of Critical Congenital Heart Disease (free)


10 – Advance care planning for patients with chronic respiratory diseases: a systematic review of preferences and practices – Thorax (link to abstract – $ for full-text)

Commentary: Doctors rarely discuss end-of-life care for chronic lung conditions – Reuters (free)

Related guideline: An Official American Thoracic Society Clinical Policy Statement: Palliative Care for Patients with Respiratory Diseases and Critical Illnesses (free)


Tue, December 5 – 10 Stories of The Day!

5 Dec,2017


1 – Association of Overlapping Surgery With Increased Risk for Complications Following Hip Surgery: A Population-Based, Matched Cohort Study – JAMA Internal Medicine (free)

Editorial: Overlapping Surgery – Perspectives From the Other Side of the Table (free)

Commentaries: Study: Overlapping surgeries boost complication risks – Becker’s Hospital Review (free) AND Does Overlapping Surgery Increase Complication Risk After Hip Surgery? – The JAMA Network (free)


2 – Cheese consumption and risk of cardiovascular disease: a meta-analysis of prospective studies – European Journal of Nutrition (link to abstract – $ for full-text)

Commentary: Eating 40g of cheese a day may reduce heart attack and stroke risk – NHS Choices (free)

Related meta-analysis: Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose–response meta-analysis of prospective cohort studies – European Journal of Epidemiology (free)


3 – WHO reviewing data on Sanofi dengue vaccine, urges limited use – Reuters (free)

Related: Brazil recommends restrictions on Sanofi dengue vaccine – Reuters (free) AND Sanofi restricts dengue vaccine but downplays antibody enhancement – CIDRAP (free) AND New dengue vaccine could worsen disease in some people – STAT (free)


4 – 2017 Update in perioperative medicine: 6 questions answered – Cleveland Clinic Journal of Medicine (free)


5 – Pulmonary embolus in the ED – Which patients require systemic thrombolytics? – emDocs (free)


6 – An Unconscious Patient with a DNR Tattoo – New England Journal of Medicine (free)

Commentary: His tattoo said “do not resuscitate.” Doctors wanted another opinion – The New York Times (free)


7 – Headline vs. study: The unbearable heaviness of false hope – HealthNews Review (free)


8 – Our Review Criteria – HealthNewsReview (free)

“Such a great list! Ten Criteria for Reviewing a News Article on Health. Cost, harms, quality of evidence, disease-mongering, conflict of interest, etc.” (RT @CaulfieldTim see Tweet)


9 – Richard Lehman’s journal review, 4 December 2017 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.


10 – Cognitive trajectories from infancy to early adulthood following birth before 26 weeks of gestation: a prospective, population-based cohort study – Archives of Disease in Childhood (free)

Commentary: Does Cognition in Children Born Extremely Preterm Catch Up by Early Adulthood? – Journal Watch (free)


Mon, December 4 – 10 Stories of The Day!

4 Dec,2017


1 – SIGN Guidelines on Pharmacological management of glycaemic control in people with type 2 diabetes & Management of diabetes – Scottish Intercollegiate Guidelines Network (free guidelines and resources) (via @kamleshkhunti)


2 – HIV Prevention Efforts and Incidence of HIV in Uganda – New England Journal of Medicine (free)

Commentaries: Combination HIV prevention reduces new infections by 42 percent in Ugandan district – National Institutes of Health (free) AND Combination HIV Prevention Reduces Infections – MD Magazine (free)


3 – 2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants – Journal of The American College of Cardiology (free)

Commentary and Summary: Consensus for Management of Bleeding on Oral Anticoagulants – American College of Cardiology, Latest in Cardiology (free)


4 – Clinical Guidelines Synopsis: Diagnostic Testing for Obstructive Sleep Apnea in Adults – JAMA (free)


5 – Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials – The BMJ (free)

Commentaries: Evidence Insufficient to Recommend Prenatal Vitamin D Supplementation, Researchers Say – Physician’s First Watch (free) AND Jury Still Out on Vitamin D Supplements in Pregnancy – MedPage Today (free registration required)


6 – Risk of death associated with new benzodiazepine use among persons with Alzheimer disease: A matched cohort study – International Journal of Geriatric Psychiatry (link to abstract – $ for full-text) (RT @Deprescribing see Tweet)

Commentaries: Benzodiazepines linked to increased risk of death among Alzheimer’s disease patients – News Medical (free) AND Benzodiazepines Tied to a 41% Increased Mortality Risk in AD – Medscape (free registration required)


7 – Rational decision making in medicine: Implications for overuse and underuse – Journal of Evaluation in Clinical Practice (free) (via @AllenFrancesMD)


8 – Cardiovascular and type 2 diabetes morbidity and all-cause mortality among diverse chronic inflammatory disorders – Heart (free)


9 – Disparities in the Quality of Cardiovascular Care Between HIV‐Infected Versus HIV‐Uninfected Adults in the United States: A Cross‐Sectional Study – Journal of The American Heart Association (free)

Commentaries: HIV-positive adults are under-treated for cardiovascular problems compared to those without HIV – UCLA Research Alert (free) AND HIV patients less likely to be prescribed aspirin, statins despite increased cardiovascular risk – Cardiovascular Research (free)

Related: Cardiovascular risk and dyslipidemia among persons living with HIV: a review – BMC Infectious Diseases (free)


10 – European Thyroid Association Guidelines for Ultrasound Malignancy Risk Stratification of Thyroid Nodules in Adults: The EU-TIRADS – European Tyroid Journal (free)

Related guideline: ACR Thyroid Imaging, Reporting and Data System (TI-RADS): White Paper of the ACR TI-RADS Committee – Journal of the American College of Radiology (free PDF)


Fri, December 1 – 10 Stories of The Day!

1 Dec,2017


1 – World AIDS Day, 1 December 2017 – World Health Organization (free)


2 – Book: Cardiovascular, respiratory, and related disorders – Disease Control Priorities, 3rd Edition (free)

Press Release: Disease Control Priorities, 3rd Edition Launches Volume on Cardiovascular, Respiratory, and Related Disorders (free)

Summary: Cardiovascular, respiratory, and related disorders: key messages from Disease Control Priorities, 3rd edition – The Lancet (free registration required)

Previous volumes: 1 – Essential Surgery / 2 – Reproductive, Maternal, Newborn, and Child Health / 3 – Cancer / 4 – Mental, Neurological, and Substance Use Disorders / 5 – Injury Prevention and Environmental Health / 6 – Major Infectious Diseases (all free)


3 – Guideline: Protecting, promoting and supporting breastfeeding in facilities providing maternity and newborn services – World Health Organization (free)


4 – Guideline: Outbreak Response and Incident Management: SHEA Guidance and Resources for Healthcare Epidemiologists in United States Acute-Care Hospitals – Infection Control and Hospital Epidemiology (free)

Commentary: New document guides hospitals in responding to infectious disease outbreaks – Society for Healthcare Epidemiology of America (free)


5 – Marriage and risk of dementia: systematic review and meta-analysis of observational studies – Journal of Neurology Neurosurgery and Psychiatry (free)

Commentaries: Single people have a higher risk of dementia – OnMedica (free) AND Marriage linked to lower dementia risk – Reuters (free)


6 – Worldwide burden of cancer attributable to diabetes and high body-mass index: a comparative risk assessment – The Lancet Diabetes & Endocrinology (free)

Editorial: Diabetes and adiposity: a heavy load for cancer (free)

Commentaries: Diabetes and obesity together responsible for nearly 800,000 cancers worldwide – Imperial College London (free) AND ‘Alarming’ rise in cancer rates driven by diabetes, obesity – Medical News Today (free) AND Nearly 6% of cancers worldwide are attributable to diabetes and obesity – eCancer News (free)


7 – Conventional Polysomnography Is Not Necessary for the Management of Most Patients with Suspected Obstructive Sleep Apnea. Noninferiority, Randomized Controlled Trial – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)

Commentary: Conventional Polysomnography vs. Home Testing for Obstructive Sleep Apnea – Journal Watch (free) AND Home Sleep Testing OK for Evaluating Suspected Sleep Apnea – MedPage Today (free registration required)

Related: Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline (free)


8 – Unnecessary Tests and Treatment Explain Why Health Care Costs So Much – Scientific American (free)


9 – Big data often yields small returns. Here’s how to fix that – STAT (free)


10 – Diagnostic Accuracy of Pediatric Teledermatology Using Parent-Submitted Photographs: A Randomized Clinical Trial – JAMA Dermatology (link to abstract – $ for full-text)

Commentaries: Parent-Supplied Photos Allow Pediatric Dermatology Diagnoses without an Office Visit in Most Instances – Children’s Hospital of Philadelphia (free) AND Smartphone pics may be sharp enough for dermatology diagnosis – Reuters (free)


Thu, November 30 – 10 Stories of The Day!

30 Nov,2017


1 – Guideline: Asthma: diagnosis, monitoring and chronic asthma management – National Institute for Health and Care Excellence (free)

News release: New ways to diagnose and manage asthma can improve care, says NICE (free)

Commentaries: NICE changes guidelines on asthma – PharmaTimes (free) AND NICE releases the latest asthma management standards – News Medical (free)


2 – The potential impact of food taxes and subsidies on cardiovascular disease and diabetes burden and disparities in the United States – BMC Medicine (free) (via @ArsenaultBenoit)

Related Guideline: Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization (free)

Related articles: Reducing US cardiovascular disease burden and disparities through national and targeted dietary policies: A modelling study – PLOS Medicine (free) AND Taxes and Subsidies for Improving Diet and Population Health in Australia: A Cost-Effectiveness Modelling Study – PLOS Medicine (free) AND Policy lessons from health taxes: a systematic review of empirical studies – BMC Public Health (free)


3 – Association Between Wait Time and 30-Day Mortality in Adults Undergoing Hip Fracture Surgery – JAMA (link to abstract – $ for full-text)

Commentaries: Delaying Surgery for Hip Fracture for More Than One Day Associated with Small Increased Risk of Death – The JAMA Network (free) AND Delaying Hip Fracture Surgery for 1 Day Tied to Higher Mortality Risk – Physician’s First Watch (free) AND Emergency Hip Surgery Best Done Within 24 Hours – Medscape (free registration required)


4 – Gene Therapy Shows Promise For A Growing List Of Diseases – NPR (free)


5 – A three-talk model for shared decision making: multistage consultation process – The BMJ (free)


6 – Treatment eligibility and retention in clinical HIV care: A regression discontinuity study in South Africa – PLOS Medicine (free)

Commentary: Immediate ART treatment improves retention rates – Boston University School of Medicine (free)


7 – Platelet Transfusion for Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update (free)


8 – European Society of Cardiology: Cardiovascular Disease Statistics 2017 – European Journal of Cardiology (free)

“The European Atlas of Cardiology brings together data from 56 countries to demonstrate the prevalence and cost of cardiovascular disease, and the need to utilise resources more effectively” (RT @OUPMedicine see Tweet)


9 – Computerised decision support can improve antibiotic prescribing in hospitals – NIHR Signal (free)

Original Article: The effectiveness of computerised decision support on antibiotic use in hospitals: A systematic review – PLOS One (free)


10 – Palliative Care Eligibility, Symptom Burden, and Quality-of-Life Ratings in Nursing Home Residents – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Nursing home residents eligible for palliative care often don’t get it – Reuters (free) AND Most nursing home residents eligible for palliative care but lack access – MedicalXpress (free)


Wed, November 29 – 10 Stories of The Day!

29 Nov,2017


1 – World Malaria Report 2017 – World Health Organization (free)

News release: Global response to malaria at crossroads (free)

“After unprecedented global success in malaria control, progress has stalled”


2 – Effect of Oral Capsule– vs Colonoscopy-Delivered Fecal Microbiota Transplantation on Recurrent Clostridium difficile Infection: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Comparison of Fecal Transplant Using Capsule vs Colonoscopy to Prevent Clostridium Difficile Infection – The JAMA Network (free) AND New evidence suggests there’s a much easier way to get a fecal transplant – Quartz (free) AND Fecal transplant by capsule may match colonoscopy for C diff – CIDRAP (free)

Related: Faecal transplant effectively treats recurrent or unresponsive Clostridium difficile – NIHR Signal (free)


3 – Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis – The BMJ (free)

Commentary: Comparison of Oral Anticoagulants for Preventing Stroke in AF – MPR (free)


4 – The Value-Based Payment Modifier: Program Outcomes and Implications for Disparities – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Pay-for-performance fails to perform – Harvard Medical School, via ScienceDaily (free)

Related: The Effects of Pay-for-Performance Programs on Health, Health Care Use, and Processes of Care: A Systematic Review – Annals of Internal Medicine (free) AND Value-Based Purchasing: Time for Reboot or Time to Move On? by Ashish K. Jha, MD – The JAMA Forum (free)


5 – Tens of thousands dying from $30 billion fake drugs trade, WHO says – Reuters Health (free)

Related: About 11 percent of drugs in poor countries are fake, U.N. says – Associated Press (free)


6 – Five ways to fix statistics – Nature (free)

“As debate rumbles on about how and how much poor statistics is to blame for poor reproducibility, Nature asked influential statisticians to recommend one change to improve science. The common theme? The problem is not our maths, but ourselves”.


7 – Richard Lehman’s journal review, 27 November 2017 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.


8 – Indications and practical approach to non-invasive ventilation in acute heart failure – European Heart Journal (free)


9 – Long-term effects of glucocorticoids on function, quality of life, and survival in patients with Duchenne muscular dystrophy: a prospective cohort study – The Lancet (link to abstract – $ for full-text)

Commentaries: Glucocorticoids offer long-term benefits for patients with Duchenne muscular dystrophy – Children’s National Health System, via ScienceDaily (free)


10 – Aerobic exercise moderately reduces depressive symptoms in new mothers – NIHR Signal (free)

Original article: Does aerobic exercise reduce postpartum depressive symptoms? a systematic review and meta-analysis – British Journal of General Practice (free)

“Involving new mothers in group exercise programmes, or advising them on an exercise of their choice, reduced depressive symptoms compared with usual care” (RT @NIHR_DC see Tweet)


Tue, November 28 – 10 Stories of The Day!

28 Nov,2017


1 – Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis – Canadian Medical Association Journal (free)

Commentaries: New HIV guideline outlines cost-effective prevention strategies for high-risk people – ScienceDaily (free)

Related Free Online Course (Starts Dec 04): PrEParing: PrEP for Providers and Patients – Johns Hopkins University and Coursera

Related guidance: WHO implementation tool for pre-exposure prophylaxis of HIV infection (free) AND Summary: WHO implementation tool for pre-exposure prophylaxis (PrEP) of HIV infection (free)


2 – Pharmacologic Treatment of Seasonal Allergic Rhinitis: Synopsis of Guidance From the 2017 Joint Task Force on Practice Parameters – Annals of Internal Medicine (free)


3 – 2017 Roadmap for Innovation—ACC Health Policy Statement on Healthcare Transformation in the Era of Digital Health, Big Data, and Precision Health – Journal of The American College of Cardiology (free)

News Release: ACC’s Innovation Roadmap Provides Framework for Future of Care Delivery (free)

Summary with key points to remember: ACC Statement on Transforming Cardiovascular Care Through Innovation (free)


4 – Prevalence of Prior Cancer Among Persons Newly Diagnosed With Cancer: An Initial Report From the Surveillance, Epidemiology, and End Results Program – JAMA Oncology (free)

Commentary: How Common Are New Cancers in Cancer Survivors? – The JAMA Network (free) AND New cancers common in cancer survivors – OnMedica (free)


5 – The Motivational Impact of Wearable Healthy Lifestyle Technologies: A Self-determination Perspective on Fitbits With Adolescents – American Journal of Health Education (free)

Commentaries: Young people oppose Fitbits in schools – The Conversation (free) AND Activity Trackers Don’t Always Work the Way We Want Them To – The New York Times (10 articles per month are free) AND Fashionable FitBits discourage young teens from exercising, study finds – MedicalXpress (free)


6 – Sinusitis Mimics: ED-relevant pearls and pitfalls – emDocs (free)


7 – Adherence to a Healthy Lifestyle is Associated With a Lower Risk of Diverticulitis among Men – American Journal of Gastroenterology (link to abstract – $ for full-text)

Commentary: Unhealthy lifestyle may cause half of diverticulitis cases – Reuters (free)


8 – Does contrast cause kidney injury? The evidence – First10EM (free)


9 – SACN-COT statements on potassium-based sodium replacers – Public Health England (free)

Commentary: Experts urge use of salt alternative in food products – The Guardian (free)


10 – Faecal transplant effectively treats recurrent or unresponsive Clostridium difficile – NIHR Signal (free)

Original article: Systematic review with meta-analysis: the efficacy of faecal microbiota transplantation for the treatment of recurrent and refractory Clostridium difficile infection – Alimentary Pharmacology and Therapeutics (link to abstract – $ for full-text)


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