Open access

Mon, November 6 – 10 Stories of The Day!



1 – European Guidelines for treatment of HIV-positive adults – European AIDS Clinical Society (free)

Commentary: New EACS treatment guidelines – Aidsmap (free) AND EACS updates HIV guidelines for adults – Healio (free registration required)


2 – Effect of Sertraline on Depressive Symptoms in Patients With Chronic Kidney Disease Without Dialysis Dependence: The CAST Randomized Clinical Trial – JAMA (free)

Editorial: Treating Depression in Patients With Advanced CKD: Beyond the Generalizability Frontier (free)

Commentary: Standard Antidepressant May Not Help Patients with Chronic Kidney Disease – UT Southwestern Medical Center, via NewsWise (free)

“Not only doesn’t help treat moderate depression, sertraline causes worse nausea (NNH=8) & diarrhea (NNH=10)” (RT @AnilMakam see Tweet 1 and Tweet 2)


3 – Working with influenza-like illness: Presenteeism among US health care personnel during the 2014-2015 influenza season – American Journal of Infection Control (free)

Commentaries: 4 in 10 healthcare professionals work when they’re sick, risking patients – HealthCare Finance (free) AND Four in 10 Healthcare Personnel Work While Sick – Medscape (free registration required) AND Four in 10 HCPs Work While Experiencing Flu-Like Illness, Says Survey – MPR (free)


4 – Cardiovascular, respiratory, and related disorders: key messages from Disease Control Priorities, 3rd edition – The Lancet (free registration required)


5 – Testing for chronic hepatitis B and C: a global perspective – BMC Infectious Diseases (free)


6 – Frequent sugar-sweetened beverage consumption and the onset of cardiometabolic diseases: cause for concern? – Journal of the Endocrine Society (free)

Commentaries: Just two sugary drinks per week may raise type 2 diabetes risk – Medical News Today (free) AND Sugar-sweetened drinks raise risk of diabetes, metabolic syndrome – The Endocrine Society, via EurekAlert (free)


7 – Choosing Wisely: Twenty Things Physicians and Patients Should Question – American Society for Clinical Pathology (free)

Commentary: More Lab Tests Deemed Inappropriate – Medscape (free registration required)

See more on the Choosing Wisely initiative in our April 5 issue (see #6)


8 – What We Know About Tuberculosis Transmission: An Overview – The Journal of Infectious Diseases (free) (RT @greg_folkers see Tweet)


9 – Fiber Intake and Survival After Colorectal Cancer Diagnosis – JAMA Oncology (free)

Commentaries: Is Eating Fiber After Colorectal Cancer Diagnosis Associated with Lower Death Risk? – The JAMA Network (free) AND Higher Fiber Intake After Colorectal Cancer Diagnosis Tied to Improved Survival – Physician’s First Watch (free)


10 – Glucocorticosteroids for people with alcoholic hepatitis – Cochrane Library (free)

Original article: Glucocorticosteroids for people with alcoholic hepatitis – Cochrane Library (link to abstract – $ for full-text)

“We found no evidence of a difference between glucocorticosteroids and placebo or no intervention on all-cause mortality, health-related quality of life, and serious adverse events during treatment”.


Fri, November 3 – 10 Stories of The Day!



1 – Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Small Trial Raises Big Concerns That PCI In Stable Angina Is Just A Placebo – Cardiobrief (free) AND Diving Deep Into The ORBITA Trial – Cardiobrief (free) AND Unbelievable’: Heart Stents Fail to Ease Chest Pain – The New York Times (10 articles per month are free) AND ORBITA: PCI Offers No Symptom Improvement Over Sham Procedure – TCTMD (free)


2 – Balanced Crystalloids vs Saline for Critically Ill Adults – American College of Chest Physicians Annual Meeting (free abstract)

Related Study: Balanced Crystalloids vs Saline for Noncritically Ill Adults in the Emergency Department – American College of Chest Physicians Annual Meeting (free abstract)

Commentaries: Landmark Trials Deliver Evidence to Rethink Saline Use – Medscape (free registration required) AND Saline on the Ropes? Studies find balanced crystalloid fluids safer – MedPage Today (free registration required)


3 – Familial hypercholesterolaemia: identification and management – NICE Guideline (free)

News release: Inherited risk of high cholesterol should be identified and treated as early as possible, NICE says in updated guidance (free)


4 – Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association (free PDF)

Commentary: Intracranial Hemorrhage After Stroke Thrombolysis: More Questions Than Answers (free)

Top Ten Things to Know: Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke (free PDF)

Slide Set: Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in AIS (free PDF)

Related AHA/ASA Guidelines: Guidelines for the Early Management of Patients With Acute Ischemic Stroke (free) AND Guidelines for the Management of Spontaneous Intracerebral Hemorrhage (free)


5 – Cancer incidence and mortality among young adults aged 20–39 years worldwide in 2012: a population-based study – The Lancet Oncology (free)

Commentaries: Reducing the global cancer burden among young adults – The Lancet Oncology (free) AND Global burden of cancer among young adults aged 20–39 years – eCancer News (free) AND Cancer in Young Adults Disproportionately Affects Women – Medical Research (free)


6 – A ‘smart’ approach to performance drugs – ACP Internist (free)

Related: Growing use of smart drugs by students could be a recipe for disaster – The Conversation (free) AND Brain Hackers Seeking Peak Performance Use Risky Chemical Cocktails: “Smart drugs” are not clinically proven and could be dangerous – Scientific American (free) AND Universities must do more to tackle use of smart drugs, say experts – The Guardian (free) AND Tweaking brains with ‘smart drugs’ to get ahead in Silicon Valley – The Washington Post (free) AND Professors take same ‘smart drugs’ as students to keep up with workloads, claims academic – Independent (free)


6 – Seeing is Believing: Using Visual Abstracts to Disseminate Scientific Research – The American Journal of Gastroenterology (free)


7 – Opinion: Drug company sales reps should be banned from hospitals – STAT (free)


8 – Australia ends insurance subsidies for naturopathy, homeopathy, and more – Science-Based Medicine (free)


9 – Untreatable Gonorrhea Is Rapidly Spreading. Here’s What You Need to Know – TIME Health (free)


10 – Adolescent Childbirth Is Associated With Greater Framingham Risk Scores for Cardiovascular Disease Among Participants of the IMIAS (International Mobility in Aging Study) – Journal of The American Heart Association (free)

News release: Teen childbirth linked to increased risk for heart disease (free)

Commentaries: Teen childbirth linked to increased cardiovascular risk decades later – Cardiovascular Business (free) AND Study finds link between increased cardiovascular diseases and teen childbirth – News Medical (free)


Thu, November 2 – 10 Stories of The Day!



1 – The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases – Hepatology (free)


2 – The Care of Children With Congenital Heart Disease in Their Primary Medical Home – Pediatrics (free)


3 – Glaucoma: diagnosis and management – NICE Guideline (free)

News release: People at a low risk of developing glaucoma can avoid unnecessary referral, says NICE (free)


4 – Overdiagnosis and disease labels: the case of polycystic ovary syndrome – STAT (free)

Related: Are expanding disease definitions unnecessarily labelling women with polycystic ovary syndrome? – The BMJ (link to summary – $ for full-text)


5 – Bacteria Can Evolve Resistance to Drugs Before Those Drugs Are Used – The Atlantic (free)


6 – What I’ve learned from 547 doctor suicides – Pamela Wible, via (free)


7 – Mortality lower with prolonged vs. short-term IV infusion of antipseudomonal beta-lactams – ACP Hospitalist (free)

Original article: Prolonged versus short-term intravenous infusion of antipseudomonal β-lactams for patients with sepsis: a systematic review and meta-analysis of randomised trials – The Lancet Infectious Diseases (link to abstract – $ for full-text)


8 – Updated WHO recommendation on intravenous tranexamic acid for the treatment of post-partum haemorrhage – The Lancet Global Health (free)


9 – Aspirin reduces a woman’s chance of developing pre-eclampsia in pregnancy – NIHR Signal (free)

Original article: Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia – New England Journal of Medicine (link to abstract – $ for full-text)


10 – Vaginal cleansing before caesarean delivery reduces risk of infections – NIHR signal (free)

Original article: Vaginal Cleansing Before Cesarean Delivery: A Systematic Review and Meta-analysis – Obstetrics & Gynecology (link to abstract – $ for full-text)


Wed, November 1 – 10 Stories of The Day!



1 – Lancet Countdown: Traking Progress on Health and Climate Change (free infographics, video and other resources)

Report: The Lancet Countdown on health and climate change: from 25 years of inaction to a global transformation for public health (free registration required)

Commentaries: Health impacts of climate change already felt today – Imperial College London (free) AND How Climate Change Is Already Affecting Health, Spreading Disease – NPR Goats and Soda (free) AND Climate change already bringing disease, air pollution and heatwaves – The Guardian (free) AND Climate change isn’t just hurting the planet – it’s a public health emergency – The Guardian (free)


2 – Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study – Gut (link to abstract – $ for full-text)

Commentaries: Acid reflux drug linked to more than doubled risk of stomach cancer – study – The Guardian (free) AND Gastric Cancer Risk Doubled With Long-term PPI Use – Medscape (free registration required) AND PPI Use After H. pylori Eradication Therapy Tied to Increased Risk for Gastric Cancer – Physician’s First Watch (free)


3 – Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden – BMJ Open (free)

“Among 797 067 individuals on maintenance PPI therapy, the SIR of gastric cancer was over threefold increased (SIR=3.38, 95% CI 3.23 to 3.53)”.


4 – Review: Point of Care Ultrasound: An Overview – American College of Cardiology, Latest in Cardiology (free)

Related reviews: Ultrasonography in the emergency department – Critical Care (free) AND Clinically integrated multi-organ point-of-care ultrasound for undifferentiated respiratory difficulty, chest pain, or shock: a critical analytic review – Journal of Intensive Care (free) AND Common pitfalls in point-of-care ultrasound: a practical guide for emergency and critical care physicians – Critical Ultrasound Journal (free) AND Point-of-Care Ultrasonography by Pediatric Emergency Medicine Physicians – Pediatrics (free)


5 – 25th UEG (United European Gastroenterology) Week: Long-term aspirin use reduces the incidence of digestive cancers by up to 47% (free)

Commentaries: Long-Term Aspirin Use May Reduce Cancer Risk, Study Finds – Forbes (free) AND Aspirin slashes risk of gastrointestinal cancer – Medical News Today (free)


6 – Joint statement for the diagnosis, management, and prevention of chronic obstructive pulmonary disease for Gulf Cooperation Council countries and Middle East–North Africa region, 2017 – International Journal of Chronic Obstructive Pulmonary Disease (free)


7 – Mefloquine for preventing malaria during travel to endemic areas – Cochrane Library (free)

News release: Can mefloquine prevent malaria during travel to areas where the disease is widespread? (free)

Commentary: Cochrane review provides clarity about safety of mefloquine for preventing malaria in travelers – News Medical (free)


8 – Enjoyment of Spicy Flavor Enhances Central Salty-Taste Perception and Reduces Salt Intake and Blood Pressure – Hypertension (free)

Commentary: Can spicy foods curb salt cravings or lower blood pressure? – Reuters (free) AND Need to cut down on salt? Try something spicy instead – Medical News Today (free)


9 – Economic impact of palliative care among elderly cancer patients – presented at: 2017 Palliative and Supportive Care in Oncology Symposium (free abstract)

Commentaries: Palliative Care Associated With Decreased Costs For Patients With Advanced Cancer – Oncology Nurse Advisor (free) AND Early Palliative Care Is Key Driver in Reducing Costs – Medscape (free registration required)

Related study: Effect of Palliative Care on Aggressiveness of End-of-Life Care Among Patients With Advanced Cancer – Journal of Oncology Practice (link to abstract – $ for full-text) AND Commentaries: Palliative Care May Substantially Decrease Health-Care Utilization in Patients With Advanced Cancer – ASCO Post (free) AND End-of-Life Palliative Care Lowered Utilization for Patients With Cancer – AJMC (free)

Related guideline: Integration of Palliative Care Into Standard Oncology Care: American Society of Clinical Oncology Clinical Practice Guideline Update (free)


10 – Classification of Cough as a Symptom in Adults and Management Algorithms: CHEST Guideline and Expert Panel Report (free PDF)

See also other recent CHEST guidelines on the management of cough in specific populations: Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold – CHEST Expert Panel Report (free) AND Chronic Cough Due to Gastroesophageal Reflux in Adults (free) AND Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer (free) AND Cough in the athlete (free) AND Occupational and Environmental Contributions to Chronic Cough in Adults (free) AND Treatment of Unexplained Chronic Cough (free) AND Use of Management Pathways or Algorithms in Children With Chronic Cough: CHEST Guideline and Expert Panel Report (free) AND Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis: CHEST Guideline and Expert Panel Report (free)



Tue, October 31 – 10 Stories of The Day!



1 – Global tuberculosis report 2017 – World Health Organization (free PDF)

News release: WHO report signals urgent need for greater political commitment to end tuberculosis (free)

Commentaries: Tuberculosis world’s top infectious killer; UN health agency calls for political action to stop spread – UN News Center (free) AND Pandemic alert: Tuberculosis is world’s No. 1 infectious killer – CNBC (free) Despite progress, WHO paints ‘grim’ picture of global TB – CIDRAP (free)


2 – 2017 AHA/ACC/HRS Guideline for Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death (free PDF)

News release: Societies Detail Treatment for Patients With Ventricular Arrhythmias (free)

See also: Executive summary (free PDF) AND Top Ten Things to Know (free PDF) AND Slide Set (free PDF)


3 – PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock – New England Journal of Medicine (free)

Editorial: Back to the Future in Cardiogenic Shock — Initial PCI of the Culprit Lesion Only (free)

Commentaries: CULPRIT-SHOCK Disputes Benefit of Immediate Multivessel PCI in Patients With Cardiogenic Shock – TCTMD (free) AND CULPRIT-SHOCK: Culprit Lesion Only PCI Vs. Immediate Multivessel PCI in Cardiogenic Shock – American College of Cardiology, Latest in Cardiology (free)


4 – Prenatal Exposure to Acetaminophen and Risk of ADHD – Pediatrics (free)

Commentaries: An Association Between Prenatal Acetaminophen Use and ADHD: The Benefits of Large Data Sets – Pediatrics (free) AND Long-term Acetaminophen Use in Pregnancy and ADHD – 2 Minute Medicine (free) AND Study links acetaminophen in pregnancy to ADHD, but experts question results – CNN (free)


5 – Policy Statement: Cord Blood Banking for Potential Future Transplantation – American Academy of Pediatrics (free)

News release: Updated policy reaffirms value of public over private cord blood banks (free)

Commentaries: Pediatrics Group Updates Recommendations on Cord Blood Banking – Physician’s First Watch (free)


6 – Duration of Breastfeeding and Risk of SIDS: An Individual Participant Data Meta-analysis – Pediatrics (link to abstract – $ for full-text)

Commentary: Breastfeeding for two months halves risk of SIDS – University of Virginia Health System, via ScienceDaily (free)


7 – Is there a conflict of interest behind your cancer diagnosis? – STAT (free)


8 – Richard Lehman’s journal reviews, 30 October 2017 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.


9 – Electronic cigarette use and smoking initiation among youth: a longitudinal cohort study – Canadian Medical Association Journal (free)

Commentary: E-cigarette use by high school students linked to cigarette smoking – ScienceDaily (free)


10 – Review: So you think it is sepsis: considerations beyond lung and urine in the sick patient without a source – emDocs (free)


Page 3 of 10912345...102030...Last »

Share with you friends

Follow Us

Share Button

New! Subscribe to our 10 Stories of the Day.


Weekly or Less often