Wed, November 28 – 10 Stories of The Day!

1 – Global, regional, and national burden of Alzheimer’s disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 – The Lancet Neurology (free)

Invited Commentary: Statistics on the burden of dementia: need for stronger data – The Lancet (free)

“In 2016, globally, 43·8 million individuals lived with dementia, increased from 20.2 million in 1990; dementia was the fifth leading cause of death globally (2·4 million) and more women than men had dementia” (via @TheLancet see Tweet with infographic)

2 – Sex differences in faecal occult blood test screening for colorectal cancer – British Journal of Surgery (free)

Commentaries: Screen­ing for colorectal can­cer spares male pa­tients from in­tense treat­ments – University of Helsinki (free) AND FOBT Colorectal Cancer Screening Only Effective in Men – Medscape (free registration required)

3 – Comparative risk of harm associated with trazodone or atypical antipsychotic use in older adults with dementia: a retrospective cohort study – Canadian Medical Association Journal (free)

Commentaries: Study finds alternative to antipsychotic medication for seniors also has drawbacks – The Globe and Mail (free) AND Trazadone linked to more falls, major fractures in dementia patients – UPI (free) AND Trazadone associated with similar risk of falls and major fractures as antipsychotics in seniors with dementia – Canadian Medical Association Journal (free) AND Aggression in Dementia: Alternatives to Antipsychotics Also Have Side Effects – MedicalResearch.com (free)

4 – Review: Therapy and Management of Pneumocystis jirovecii – Infection – Journal of Fungi (free)

This article belongs to the Special Issue Treatments for Fungal Infections (free reviews)

5 – Arterial thrombosis in unusual sites: A practical review – European Journal of Haematology (free)

6 – Survey Snapshot: What Would Accelerate the Adoption of Value-Based Care? – NEJM Catalyst (free)

7 – Ten simple rules for collaboratively writing a multi-authored paper – PLOS Computational Biology (free) (via @Abraham_RMI)

8 – Assessment of Pregabalin Postapproval Trials and the Suggestion of Efficacy for New Indications: A Systematic Review – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Some research may be encouraging ineffective prescriptions, says new study – McGill University (free)

“Our point is not to condemn these individual trials. Instead, we are saying that—when you zoom out and look at what’s happening at the level of the forest—the trees begin to look less healthy.” (from McGill University)

9 – Viewpoint: A Global Public Health Victory for Tobacco Plain-Packaging Laws in Australia – JAMA Internal Medicine (free)

10 – Long-Term Protection After Fractional-Dose Yellow Fever Vaccination: Follow-up Study of a Randomized, Controlled, Noninferiority Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Study affirms fractional dosing with yellow fever vaccine – CIDRAP (free)

Related: Fractional-Dose Yellow Fever Vaccination (free research and perspective)