Open access
Open access
Powered by Google Translator Translator

Wed, May 23 – 10 Stories of The Day!

23 May, 2018 | 00:05h | UTC

 

1 – Low-dose corticosteroids for adult patients with septic shock: a systematic review with meta-analysis and trial sequential analysis – Critical Care Medicine (free for a limited period)

Source: Critical Care Reviews Newsletter

“In adults with septic shock treated with low dose corticosteroids, short- and longer-term mortality are unaffected, adverse events increase, but duration of shock, mechanical ventilation and ICU stay are reduced”.

 

2 – Aldosterone Antagonist Therapy and Mortality in Patients With ST-Segment Elevation Myocardial Infarction Without Heart Failure: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)

Invited Commentary: Mineralocorticoid Receptor Antagonists in ST-Segment Elevation Myocardial Infarction – JAMA Internal Medicine (free for a limited period)

Aldosterone antagonists are beneficial for patients with STEMI and reduced ejection fraction. This meta-analysis suggests that patients with STEMI and LVEF greater than 40% or without heart failure also have improved outcomes with aldosterone antagonists.

 

3 – Effect of More vs Less Frequent Follow-up Testing on Overall and Colorectal Cancer–Specific Mortality in Patients With Stage II or III Colorectal Cancer: The COLOFOL Randomized Clinical Trial – JAMA (free for a limited period)

Related Trial: Association Between Intensity of Posttreatment Surveillance Testing and Detection of Recurrence in Patients With Colorectal Cancer (free for a limited period)

Commentaries: Surveillance intensity not associated with earlier detection of recurrence or improved survival in colorectal cancer – MedicalXpress (free) AND CRC: No Increase in Survival with Stepped-Up Surveillance – MedPage Today (free registration required) AND CRC recurrence surveillance studies: No benefit to high-intensity strategy – Oncology Practice (free)

 

4 – Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma – New England Journal of Medicine (free)

Related Article: Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma – New England Journal of Medicine (free)

Editorial: New Biologics for Asthma (free)

Commentary: Dupilumab Improves Severe Asthma – NEJM Physician’s First Watch (free)

 

5 – Five-Year Outcomes with PCI Guided by Fractional Flow Reserve – New England Journal of Medicine (free)

Commentary: FFR in PCI for Stable CAD: Lasting Benefit Shown by FAME 2, SCAAR Data – TCTMD (free)

 

6 – Pro/Con Debate: CTA as the Initial Test in Stable Angina – American College of Cardiology

Pro: Coronary CTA Should Be the Initial Test in Most Patients with Stable Chest Pain (free)

Con: Coronary CTA Should Be the Initial Test in Most Patients with Stable Chest Pain (free)

 

7 – How PrEP, the pill to prevent HIV, may be fueling a rise in other STDs – Vox (free)

Original Meta-Analysis: Effects of Pre-exposure Prophylaxis for the Prevention of Human Immunodeficiency Virus Infection on Sexual Risk Behavior in Men Who Have Sex With Men: A Systematic Review and Meta-analysis – Clinical Infectious Diseases (link to abstract – $ for full-text)

See also: Guidelines on HIV Pre-exposure Prophylaxis (all free)

 

8 – Associations of egg consumption with cardiovascular disease in a cohort study of 0.5 million Chinese adults – Heart (free)

Commentaries: BMJ’s scrambled message on eggs and heart disease: a recipe for rotten news coverage – Health News Review (free) AND Expert reaction to eggs and CVD – Science Media Centre (free) AND No, Eating Eggs Will NOT Protect You From Cardiovascular Death – The Methods Man (free)

 

9 – Rapid Recommendations: Atraumatic (pencil-point) versus conventional needles for lumbar puncture: a clinical practice guideline – The BMJ (free)

“We issue a strong recommendation for use of atraumatic needles in all patients (adults and children) undergoing lumbar puncture because they decrease complications and are no less likely to work than conventional needles”

 

10 – New BMJ Series: Universal Health Coverage

The BMJ in partnership with The Harvard Global Health Institute are launching a collection of articles that will explore how to achieve effective Universal Health Coverage (UHC)”

Analysis: Rethinking assumptions about delivery of healthcare: implications for universal health coverage (free)

Opinion: Non-communicable diseases must be part of Universal Health Coverage (free)

Opinion: Ensuring effective investments in Universal Health Coverage at the national level (free)

Opinion: Paying and investing in community health workers accelerates universal health coverage (free)

 


Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.