Wed, March 20 – 10 Stories of The Day!

1 – Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors: ASCO and SNO Endorsement of the Congress of Neurological Surgeons Guidelines – Journal of Clinical Oncology (free)

2 – Comparison of Dual Therapies for Lowering Blood Pressure in Black Africans – New England Journal of Medicine (free for a limited period)

Commentary: Two-Drug Combos Using Popular Calcium Channel Blocker Show Superiority in Lowering Blood Pressure – American College of Cardiology (free)

3 – High-Dose Nifedipine Tied to Higher Cardiac Arrest Risk – TCTMD (free)

See also: Nifedipine linked with cardiac arrest – Pharmacy News (free) AND Common blood pressure drug may increase cardiac arrest risk – Medical News Today (free)

4 – Diagnostic Test Interpretation: Evaluating the Erythrocyte Sedimentation Rate – JAMA (free for a limited period)

5 – Outpatient treatment for people with cancer who develop a low‐risk febrile neutropaenic event – Cochrane Library (free)

Summary: Outpatient treatment for cancer patient with low-risk febrile neutropaenic event is effective – Cochrane Library (free)

Related Guideline: Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update – Journal of Clinical Oncology (free) 

6 – Pharmacologic and Nonpharmacologic Treatments for Urinary Incontinence in Women: A Systematic Review and Network Meta-analysis of Clinical Outcomes – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Behavioral therapy appears more effective than pharmacologic therapy for urinary incontinence outcomes – ACP Internist (free) AND For Urinary Incontinence, Behavioral Therapies Outperform Meds – NEJM Journal Watch (free)

7 – Best Practices for Evaluation and Treatment of Agitated Children and Adolescents (BETA) in the Emergency Department: Consensus Statement of the American Association for Emergency Psychiatry – West Journal of Emergency Medicine (free)

8 – Age, period, and cohort trends in mood disorder indicators and suicide-related outcomes in a nationally representative dataset, 2005–2017 – Journal of Abnormal Psychology (free PDF)

Commentaries: A Rise In Depression Among Teens And Young Adults Could Be Linked To Social Media Use – NPR (free) AND Mental health issues increased significantly in young adults over last decade – American Psychological Association (free)

9 – Levels of Evidence Supporting American College of Cardiology/American Heart Association and European Society of Cardiology Guidelines, 2008-2018 – JAMA (link to abstract – $ for full-text)

Commentaries: Many Guidelines For Heart Care Rely On Weak Evidence – NPR (free) AND Few heart care recommendations are based on rigorous study – News Medical (free)

10 – Diagnostic Accuracy of Point-of-Care Lung Ultrasonography and Chest Radiography in Adults With Symptoms Suggestive of Acute Decompensated Heart Failure: A Systematic Review and Meta-analysis – JAMA Network Open (free)

“The findings suggest that Lung Ultrasonography is more sensitive than Chest Radiography in detecting pulmonary edema in ADHF”