Wed, December 5 – 10 Stories of The Day!

1 – Finding the Balance Between Benefits and Harms When Using Statins for Primary Prevention of Cardiovascular Disease: A Modeling Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Statins may be significantly overprescribed for primary prevention, computer model suggests – ACP Internist (free) AND Benefits of Statins Only Exceed Harms at Higher 10-Year Risk Thresholds, Study Suggests – TCTMD (free) AND Higher Risk Thresholds May Be Needed for Starting Statins for Primary CVD Prevention, Study Suggests – NEJM Journal Watch (free) AND Statins are being overprescribed, study suggests – OnMedica (free)

2 – The Ethics of Heritable Genome Editing: New Considerations in a Controversial Area – JAMA (free for a limited period)

Related: WHO looks at standards in ‘uncharted water’ of gene editing – Reuters (free) AND The CRISPR Baby Scandal Gets Worse by the Day – The Atlantic (free) AND We need a temporary moratorium on using gene editing to create babies – STAT (free) AND Is the CRISPR baby controversy the start of a terrifying new chapter in gene editing? – VOX (free) AND First CRISPR babies: six questions that remain – Nature (free) AND ‘I feel an obligation to be balanced.’ Noted biologist comes to defense of gene editing babies – Science (free)

3 – Fasting-Evoked En Route Hypoglycemia in Diabetes (FEEHD): An Overlooked Form of Hypoglycemia in Clinical Practice – International Journal of Endocrinology (free)

Commentary: Fasting for lab tests isn’t good for patients with diabetes – Michigan State University (free)

4 – Last Month in Oncology with Dr. Bishal Gyawali: November 2018 – eCancer News (free)

5 – Review: Confounders of severe asthma: diagnoses to consider when asthma symptoms persist despite optimal therapy – World Allergy Organization Journal (free)

6 – Perspective: Potential Risks and Benefits of Mental Health Screening of Physicians – JAMA (free for a limited period)

7 – Perspective: Why the world is becoming more allergic to food – BBC (free)

8 – Clinical validation of a risk scale for serious outcomes among patients with chronic obstructive pulmonary disease managed in the emergency department – Canadian Medical Association Journal (free)

News Release: Tool identifies which patients with COPD are at risk of death, serious complications (free)

Commentary: Tool quickly identifies risk for deadly COPD complications – UPI (free)

9 – Predictors of dementia misclassification when using brief cognitive assessments – Neurology (free PDF)

Commentary: Study Finds Biases in Widely Used Dementia Identification Tests – University of Exeter (free) AND Primary Care Tests Flunk for Classifying Dementia – MedPage Today (free registration required) AND Brief Cognitive Exams Commonly Misdiagnose Dementia – NEJM Journal Watch (free)

10 – Body-weight fluctuation and incident diabetes mellitus, cardiovascular disease, and mortality: a 16-year prospective cohort study – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)

Commentaries: Weight cycling is associated with a higher risk of death – The Endocrine Society (free) AND Study: Yo-yo diets can increase death risk – UPI (free)