Tue November 12 – 10 Stories of The Day!

1 – Cannabis-based medicinal products – National Institute for Health and Care Excellence (free)

Commentaries: Drug experts on the new guidance for medicinal cannabis – The Conversation (free) AND Ian Hamilton: New guidelines for prescribing medicinal cannabis—another dashed hope for patients – The BMJ Opinion (free)

Related: Guideline for Prescribing Medical Cannabinoids in Primary Care – Canadian Family Physician (free) AND Cannabinoids for Chronic Pain – Therapeutics Initiative AND (free) Meta-Analysis: Insufficient Evidence for The Use of Cannabinoids for Treating Mental Disorders – The Lancet Psychiatry (link to abstract and commentaries) AND The Effects of Cannabis Among Adults With Chronic Pain – Annals of Internal Medicine (link to abstract and commentaries)

“In short, NICE has concluded that more research is needed before it can recommend the use of cannabis-based products for medicinal use.” (from The Conversation)

2 – Clinical Practice Guidelines for The Perioperative Nutrition, Metabolic, And Nonsurgical Support of Patients Undergoing Bariatric Procedures – 2019 Update: Cosponsored By American Association Of Clinical Endocrinologists/American College Of Endocrinology, The Obesity Society, American Society For Metabolic & Bariatric Surgery, Obesity Medicine Association, And American Society Of Anesthesiologists (free PDF)

3 – O-RADS US Risk Stratification and Management System: A Consensus Guideline from the ACR Ovarian-Adnexal Reporting and Data System Committee – Radiology (free)

4 – Results of a 6-week treatment with 10 mg prednisolone in patients with hand osteoarthritis (HOPE): a double-blind, randomised, placebo-controlled trial – The Lancet (free registration required)

Commentaries: Low-Dose Oral Prednisolone Substantially Improves Pain and Function in Hand Osteoarthritis – American College of Rheumatology (free) AND Short-term prednisolone offers HOPE for painful hand osteoarthritis – Medicine Matters (free) AND Short Course of Low-Dose Prednisolone for Painful Hand Osteoarthritis – MedicalResearch.com (free)

#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting

5 – Association of Testosterone Therapy With Risk of Venous Thromboembolism Among Men With and Without Hypogonadism – JAMA Internal Medicine (free for a limited period)

6 – A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes – Circulation (free for a limited period)

Commentaries: World-First Trial Cuts ED Wait Times and Admissions – Flinders University (free) AND Ruling Out MI Safe With 0/1-Hour High-Sensitivity Troponin: RAPID-TNT – TCTMD (free)

Related Studies/Commentaries Highlighting Problems with High-sensitivity Cardiac Troponin: Myths in Emergency Medicine: Is hs-cTnT Worth the Downstream Testing? – Emergency Medicine News (free) AND Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome – The Lancet (free study and commentaries) AND Cohort Study: The Introduction of High-sensitive Troponins Had No Impact on Survival – Journal of the American College of Cardiology (free) AND Cohort Study: High Sensitivity Cardiac Troponin May Result in Misdiagnosis of Acute Myocardial Infarction – The BMJ (free)

7 – Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups – BMC Medicine (free)

Related: Acetylsalicylic acid for primary prevention of cardiovascular events – Canadian Family Physician (free) AND Evidence evolving on aspirin as prevention – ACP Internist (free) AND Benefits and Harms of Aspirin for Primary Prevention of Cardiovascular Disease – Annals of Internal Medicine (link to abstract and commentaries) AND Aspirin for Primary Prevention: Is This the End of the Road? (selection of resources on the subject)

8 – Lipid-based nutrient supplements and all-cause mortality in children 6–24 months of age: a meta-analysis of randomized controlled trials – American Journal of Clinical Nutrition (free)

Commentaries: Nutrient supplements significantly reduce child deaths – University of California (free) AND Children receiving small-quantity lipid-based nutrient supplementary foods have lower mortality rates – American Society for Nutrition (free)

9 – Review: Sleep-Related Disorders in Neurology and Psychiatry – Deutsches Ärzteblatt international (free)

10 – Onco-Nephrology: Cancer, chemotherapy and kidney – Nephrología (free)

Related: Onco-Nephrology: Core Curriculum – American Journal of Kidney Diseases (free) AND Onco-nephrology: an appraisal of the cancer and chronic kidney disease links – Nephrology Dialysis Transplantation (free) AND Opening an onconephrology clinic: recommendations and basic requirements – Nephrology Dialysis Transplantation (free) AND Onco-nephrology: current concepts and future perspectives – Japanese Journal of Clinical Oncology (free)