Tue May 21 – 10 Stories of The Day!

#ATS2019 – Highlights from the 2019 Meeting of the American Thoracic Society

1 – Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis – JAMA (free for a limited period)

Editorial: New Phenotypes for Sepsis: The Promise and Problem of Applying Machine Learning and Artificial Intelligence in Clinical Research (free for a limited period)

Commentary: Big data reveals hidden subtypes of sepsis – University of Pittsburgh (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

2 – Early Sedation with Dexmedetomidine in Critically Ill Patients – New England Journal of Medicine (link to abstract – $ for full-text)

Just Presented at the 2019 Meeting of the American Thoracic Society.

3 – Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Sedation and controlled paralysis do not improve survival of ICU patients with ARDS – University of Pittsburgh (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

4 – Controlled Trial of Budesonide–Formoterol as Needed for Mild Asthma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Treatment Changes for Mild Asthma? – NEJM Journal Watch (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

5 – Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Large portion of patients with mild persistent asthma and low sputum eosinophils respond equally well to inhaled corticosteroids as placebo – NIH News Releases (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

6 – Nintedanib for Systemic Sclerosis–Associated Interstitial Lung Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Nintedanib slows lung function decline in SSc-associated interstitial lung disease – Medicine Matters (free)

Just Presented at the 2019 Meeting of the American Thoracic Society.

7 – Google’s AI improves accuracy of lung cancer diagnosis, study shows – STAT (free)

See also: A.I. Took a Test to Detect Lung Cancer. It Got an A. – The New York Times (10 articles per month are free)

Original Article: End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography – Nature Medicine (link to abstract – $ for full-text)

8 – Viewpoint: Millions Take Gabapentin for Pain. But There’s Scant Evidence It Works. – The New York Times (10 articles per month are free)

Related: Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain (free) AND Benefits and safety of gabapentinoids in chronic low back pain (free) AND Less is More: A Clinical Overview of Off-label Use of Gabapentinoid Drugs (link to abstract)

9 – Viewpoint: Artificial Intelligence in Health Care: Will the Value Match the Hype? – JAMA (free for a limited period)

10 – SCAI clinical expert consensus statement on the classification of cardiogenic shock – Catheterization Cardiovascular Interventions (free) (via @paomorejon)

Commentaries: SCAI releases multi-society endorsed consensus on the classification stages of cardiogenic shock – Society for Cardiovascular Angiography and Interventions (free) AND SCAI Clinical Expert Consensus Statement on Cardiogenic Shock – American College of Cardiology (free)

“Endorsed by the American College of Cardiology (ACC), the American Heart Association (AHA), the Society of Critical Care Medicine (SCCM), and the Society of Thoracic Surgeons (STS) in April 2019”