Tue, March 20 – 10 Stories of The Day!

1 – 2018 ESC Guidelines for the diagnosis and management of syncope – European Heart Journal (free for a limited period)

News release: European Society of Cardiology guidelines on syncope launched today at EHRA 2018 (free)

Related guideline: 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society (free)

2 – The 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation – European Heart Journal (free for a limited period)

News release: New EHRA Practical Guide on non-vitamin K antagonist oral anticoagulants launched (free)

3 – MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis – New England Journal of Medicine (free)

Commentaries: Prostate MRI reveals more treatable cancers, reduces overdiagnosis than standard biopsy – European Urology Association, via EurekAlert (free) AND MRI Before Biopsy Better Than TRUS in Prostate Cancer – Medscape (free registration required)

4 – Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients: An Open-Label Nonrandomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: HCV Prophylaxis Could Expand Kidney Availability – Renal & Urology News (free) AND HCV-infected kidney donors could save lives – 2 Minute Medicine (free) AND One year posttransplant, recipients of hepatitis C kidneys disease-free – Johns Hopkins Medicine, ScienceDaily (free)

5 – Physical activity, sedentary behaviour and colorectal cancer risk in the UK Biobank – British Journal of Cancer (link to abstract – $ for full-text)

Commentaries: Binge watching TV could increase bowel cancer risk in men – Imperial College London (free) AND Expert reaction to study on physical activity, sedentary behaviour and bowel cancer risk – Science Media Centre (free)

6 – Efficacy of Vaginal Estradiol or Vaginal Moisturizer vs Placebo for Treating Postmenopausal Vulvovaginal Symptoms: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Invited commentary: Rethinking the Approach to Managing Postmenopausal Vulvovaginal Symptoms (free for a limited period)

Author interview: Efficacy of Vaginal Estradiol or Moisturizer vs Placebo for Postmenopausal Vulvovaginal Symptoms (free)

Commentary: Vaginal Estradiol Offers Little Help for Postmenopausal Symptoms – Moisturizer no better than placebo gel, either – MedPage Today (free registration required)

7 – MMWR Report: Fatal Yellow Fever in Travelers to Brazil, 2018 – Centers for Disease Control and Prevention (CDC) (free)

Commentaries: Thinking of Going to Brazil? You Will Need a Yellow Fever Vaccination – The New York Times (free) AND Brazil’s yellow fever outbreak, explained – VOX (free)

8 – Richard Lehman’s journal review, 19 March 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

9 – Are shorter courses of systemic steroids as effective as conventional longer courses in the treatment of patients with flare-ups of COPD? – Cochrane Library (free)

“Information from a new large study has increased our confidence that five days of oral corticosteroids is likely to be sufficient for treatment of adults with acute exacerbations of COPD”.

10 – Suicide After Deliberate Self-Harm in Adolescents and Young Adults – Pediatrics (free)

Commentary: Young People Who Self-Harm Face Striking Increase in Suicide Risk – Physician’s First Watch (free)

“Teens who self-harm are nearly 50 times more likely to commit suicide in the next year compared with their non-self-harming peers” (via @Physns1stWatch see Tweet)