Tue, July 25 – 10 Stories of The Day!

1 – Association of History of Dizziness and Long-term Adverse Outcomes With Early vs Later Orthostatic Hypotension Assessment Times in Middle-aged Adults – JAMA Internal Medicine (free)

Invited commentary: Early Orthostatic Hypotension and Orthostatic Intolerance—More Than an Observation or Annoyance (free)

Practice Changing – Orthostatic hypotension within 1 min of standing (rather than at 3 minutes) has greater relation to falls, fracture, syncope, motor vehicle crash, and mortality.

2 – Latest European Society of Cardiology Clinical Practice Guidelines Summary Cards are now available (Atrial Fibrillation, Heart Failure, CVD Prevention, Cardio-Oncology – free PDF summaries).

See Complete list:

– Atrial Fibrillation

– Heart Failure

– European CVD Prevention in Clinical Practice

– Cardio-oncology

– Infective Endocarditis    

– Hypertrophic Cardiomyopathy

– Cardiac Pacing & CRT

– Arterial Hypertension

– Diabetes & Pre-Diabetes, CVD

– Valvular Heart Disease  

3 – Public health interventions may offer society a return on investment of £14 for each £1 spent – NIHR Signal (free)

Original article: Return on investment of public health interventions: a systematic review – Journal of Epidemiology & Community Health (free)

4 – Viewpoint: Inconsistent Guideline Recommendations for Cardiovascular Prevention and the Debate About Zeroing in on and Zeroing LDL-C Levels With PCSK9 Inhibitors – JAMA (free)

Balanced point of view regarding the use of PCSK9 Inhibitors.

5 – Update on pediatric sepsis: a review – Journal of Intensive Care (free)

Source: Critical Care Reviews Newsletter

6 – Richard Lehman’s journal review, 24 July 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals.

7 – Why are doctors plagued by depression and suicide? A crisis comes into focus – STAT News (free)

Related: Protecting interns and other physicians from depression and suicide – STAT News (free)

8 – Is cyclobenzaprine useful for pain? – Therapeutics Initiative (free)

“…cyclobenzaprine is a long-acting sedative, not a muscle relaxant, and questioning whether any potential benefits are worth the side effects”. (from TI Newsletter). “If prescribed, a dose of 5 mg at bedtime should be tried first.  Evidence suggests titration based on response and tolerability to a maximum dose of 15 mg/day, for no longer than one week”.

9 – Canadian Cardiovascular Society and Canadian Pediatric Cardiology Association Position Statement on the Approach to Syncope in the Pediatric Patient (free)

See also: Guidelines Summary: National Guideline Clearinghouse (free)

10 – Damage control resuscitation in patients with severe traumatic hemorrhage: A practice management guideline from the Eastern Association for the Surgery of Trauma (free)

See also: Guideline Summary: National Guideline Clearinghouse (free)