Tue, August 28 – 10 Stories of The Day!

1 – Effectiveness of interventions for managing multiple high-burden chronic diseases in older adults: a systematic review and meta-analysis – Canadian Medical Association Journal (free)

Commentaries: Care coordination improves health of older patients with multiple chronic diseases – CMAJ, via EurekAlert (free) AND Seniors healthier when medical care is coordinated – Reuters (free)

Related: Ten Recommendations: Designing a High-Performing Health Care System for Patients with Complex Needs (free Guidance and related perspectives) AND Multimorbidity: A Priority for Global Health Research (free research and commentaries)

2 – A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction – Circulation (free) (via @CircAHA see Tweet with Infographic)

Editorial: H₂FPEF Score: At Last, a Properly Validated Diagnostic Algorithm for Heart Failure With Preserved Ejection Fraction (free)

3 – Clinical Guideline Synopsis: Diagnosis and Treatment of Clostridium difficile Infection – JAMA (free for a limited period) (via @ABsteward and @Abraham_RMI)

Original Guideline: Clinical Practice Guidelines for Clostridium difficileInfection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) – Clinical Infectious Diseases (free)

4 – Review: Acute Clinical Care for Transgender Patients – JAMA Internal Medicine (free for a limited period) (via @CarlosdelRio7)

5 – Antithrombotic Therapy for Atrial Fibrillation: CHEST Guideline and Expert Panel Report (free PDF)

News Release: The American College of Chest Physicians updates their antithrombotic therapy guidelines for patients with atrial fibrillation (free)

6 – Clinical Report: Marijuana Use During Pregnancy and Breastfeeding: Implications for Neonatal and Childhood Outcomes – Pediatrics (free)

News Release: Counsel against marijuana use in pregnancy, breastfeeding – American Academy of Pediatrics (free)

Related Article: Marijuana Use by Breastfeeding Mothers and Cannabinoid Concentrations in Breast Milk – Pediatrics (free)

Commentaries: A Modern Conundrum for the Pediatrician: The Safety of Breast Milk and the Cannabis-Using Mother – Pediatrics (free) AND Marijuana study finds THC in breast milk up to 6 days after mom’s use – CNN (free) AND Pediatricians Put It Bluntly: Motherhood And Marijuana Don’t Mix – Kaiser Health News (free) AND Clinical report provides guidance on marijuana use in pregnancy and lactation – 2 Minute Medicine (free)

7 – #ESCCongress – Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus – New England Journal of Medicine (free for a limited period)

Commentaries: Fish oils do not prevent heart attack or strokes in people with diabetes – ESC News Releases (free) AND Omega-3 Fatty Acids Fail to Reduce CVD Events in Diabetic Patients: ASCEND – TCTMD (free)

Related Cochrane Review: Omega-3 fatty Acids for the Prevention of Cardiovascular Disease (link to abstract and commentaries)

Related Meta-Analysis: Omega-3 Fatty Acid Supplements Don’t Reduce Cardiovascular Risk (free study and commentary)

8 – #ESCCongress – Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients – New England Journal of Medicine (free for a limited period)

Editorial: Lorcaserin — Elixir or Liability? (free for a limited period)

Commentaries: CAMELLIA-TIMI 61: Weight Loss Drug Lorcaserin Did Not Increase CV Events – American College of Cardiology (free) AND Weight-Loss Drug Lorcaserin Clears Cardiovascular Safety Hurdle: CAMELLIA-TIMI 61 – TCTMD (free) AND Weight loss drug lorcaserin found safe in large study – Reuters (free)

9 – #ESCCongress – Rivaroxaban for Thromboprophylaxis after Hospitalization for Medical Illness – New England Journal of Medicine (free for a limited period)

Commentaries: VTE risk unchanged by rivaroxaban after discharge – The Hospitalist (free) AND MARINER: Rivaroxaban vs. Placebo Post-Discharge in Patients at High Risk For VTE – American College of Cardiology (free) AND MARINER: No Reduction in Death, VTE With Rivaroxaban After Discharge in Medically Ill Patients – Medscape (free registration required)

10 – #ESCCongress – Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy – New England Journal of Medicine (free for a limited period)

Editorial: Stabilizing Transthyretin to Treat ATTR Cardiomyopathy (free for a limited period)

Commentaries: Tafamidis, a Transthyretin Stabilizer, Offers Hope for Rare Cardiomyopathy – TCTMD (free) AND ATTR-ACT: Tafamidis Findings Offer Hope For Patients With ATTR-CM – American College of Cardiology (free) AND Drug reduces deaths and hospitalizations from underdiagnosed form of heart failure – Columbia University Irving Medical Center, via EurekAlert (free)