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Thu, March 21 – 10 Stories of The Day!

21 Mar, 2019 | 07:25h | UTC

 

1 – WHO consolidated guidelines on drug-resistant tuberculosis treatment – World Health Organization (free PDF)

News Release: New WHO recommendations to accelerate progress on TB – World Health Organization (free)

 

2 – WHO expert panel paves way for strong international governance on human genome editing – World Health Organization (free)

Commentaries: World Health Organization advisers call for registry of studies on human genome editing – STAT (free) AND W.H.O. Panel Demands a Registry for Human Gene Editing – The New York Times (10 articles per month are free) AND World Health Organization panel weighs in on CRISPR-babies debate – Nature (free)

 

3 – Vitamin K for reversal of excessive vitamin K antagonist anticoagulation: a systematic review and meta-analysis – Blood Advances (free)

Our findings indicate that patients on VKA therapy who have an INR between 4.5 and 10.0 without bleeding are not likely to benefit from vitamin K administration in addition to temporary VKA cessation.”

 

4 – Podcast: Update on Atrial Fibrillation: Review of the New AHA/ACC/HRS Treatment Guidelines (free)

 

5 – Perspective: Mesh Implants for Women: Scandal or Standard of Care? – JAMA (free for a limited period)

“Urogyne mesh implants have been called the “biggest medical scandal” since thalidomide and the “gold standard” treatment for stress urinary incontinence. These divergent views illustrate the complexity of the ongoing debate over their safety and efficacy.” (via @JAMA_current see Tweet)

 

6 – Clinical practice guidelines and the overuse of health care services: need for reform – Canadian Medical Association Journal (free for a limited period)

Specialty bias and fee-for-service conflicts of interest threaten the validity of clinical practice guidelines and may lead to overdiagnosis, overtreatment and increasing health care costs.”

 

7 – Scientists rise up against statistical significance – Nature (free)

Editorial: It’s time to talk about ditching statistical significance – Nature (free)

Related: What a nerdy debate about p-values shows about science — and how to fix it – VOX (free) AND Big names in statistics want to shake up much-maligned P value – Nature News (free) AND ‘One-size-fits-all’ threshold for P values under fire – Nature News (free) AND Statisticians issue warning over misuse of P values – Nature News (free) AND Understanding common misconceptions about p-values – The 20% Statistician (free) AND PulmCrit- .050 shades of grey in p-value cutoffs (free) AND Statistical tests, P values, confidence intervals, and power: a guide to misinterpretations – European Journal of Epidemiology(free)

“We are not calling for a ban on P values. . . Rather, and in line with many others over the decades, we are calling for a stop to the use of P values in the conventional, dichotomous way.” (via @ericmjohnson)

 

8 – The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study – The Lancet Psychiatry (free)

Commentaries: Cannabis and psychosis: triangulating the evidence – The Lancet Psychiatry (free) AND Expert reaction to daily cannabis use, potency and psychosis – Science Media Centre (free) AND Daily or high-potency cannabis increases risk of psychotic disorder, study finds – CNN (free) AND Daily cannabis and skunk users run higher psychosis risk – Reuters (free)

 

9 – Psychosis with Methylphenidate or Amphetamine in Patients with ADHD – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Some ADHD medicines may increase psychosis more than others, ‘real-world’ data show – STAT (free) AND With ADHD, amphetamine has double the psychosis risk of methylphenidate – Reuters (free) AND Big data study identifies drugs that increase risk of psychosis in youth with ADHD – McLean Hospital (free)

 

10 – Long-Term Consumption of Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Mortality in US Adults – Circulation (free PDF)

Commentaries: ‘Just one sugary drink a day’ linked to health problems – NHS Choices (free) AND Sugary drinks linked to higher risk of premature death, especially for women, study says – CNN (free) AND Sugary drinks could raise risk of early deaths finds study – News Medical (free)

 


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