Thu, January 18 – 10 Stories of The Day!

1 – Household-Contact Investigation for Detection of Tuberculosis in Vietnam – The New England Journal of Medicine (free)

Quick Take Video Summary: Contact Investigation for Tuberculosis (free)

2 – Interventions to increase tuberculosis case detection at primary healthcare or community-level services – Cochrane Library (free)

Summary: Interventions to increase the number of tuberculosis cases being diagnosed – Evidently Cochrane (free)

Commentary: Cochrane review of effectiveness of strategies to improve access to treatment for TB – Liverpool School of Tropical Medicine, via EurekAlert (free)

3 – Long-Term Follow-up of Monoclonal Gammopathy of Undetermined Significance – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Monoclonal Gammopathy of Undetermined Significance: Risk for Progression to Cancer, Other Disorders Examined – Physician’s First Watch (free) AND Patients with blood cancer precursor at risk of developing cancer even after 30 years – Mayo Clinic, via EurekAlert (free)

4 – Catalogue of Bias – Centre for Evidence-Based Medicine, University of Oxford (free)

“25 biases affecting evidence on health kick off the new @CebmOxford Catalog of Bias” (via @hildabast see Tweet)

5 – Identifying older adults at risk of harm following elective surgery: a systematic review and meta-analysis – BMC Medicine (free)

Commentary: Age itself is not a risk factor for complications after surgery among older patients – OnMedica (free)

“Q: What predicts poor outcome after elective surgery in older people?

A: Frailty, cognitive impairment, depression, smoking but NOT age per se”. (via @trishgreenhalgh see Tweet)

6 – Richard Smith: The corruption of medical language – The BMJ Opinion (free)

Related: It’s not just you: science papers are getting harder to read – Nature (free) ‘It’s time to make sure research is understandable to all’ – The Telegraph (free) AND Scientific language is becoming more informal – Nature (free)

“Too often, academic journals are filled with complex language and turgid prose, which is intended not to inform the reader but to ennoble the writer”. (via @bmj_latest see Tweet)

7 – Red and processed meat consumption and breast cancer: UK Biobank cohort study and meta-analysis – European Journal of Cancer (link to abstract – $ for full-text)

Commentaries: Processed meat ‘cancer risk’ in older women – OnMedica (free) AND Consumption of processed meat may increase the risk of breast cancer, according to a new study – MedicalXpress (free)

8 – Review: What works in inclusion health: overview of effective interventions for marginalised and excluded populations – The Lancet (free registration required)

Related Article: Morbidity and mortality in homeless individuals, prisoners, sex workers, and individuals with substance use disorders in high-income countries: a systematic review and meta-analysis – The Lancet (free) AND Commentary: Inclusion health: addressing the causes of the causes (free)

9 – Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial – The Lancet (free)

Commentaries: Learning from TARDIS: time for more focused trials in stroke prevention – The Lancet (free) AND Triple Antiplatelets for Reducing Dependency After Ischaemic Stroke – TARDIS – American College of Cardiology, Latest in Cardiology (free)

“Among patients with recent cerebral ischaemia, intensive antiplatelet therapy did not reduce the incidence and severity of recurrent stroke or TIA, but did significantly increase the risk of major bleeding. Triple antiplatelet therapy should not be used in routine clinical practice”.

10 – Early Recurrence and Major Bleeding in Patients With Acute Ischemic Stroke and Atrial Fibrillation Treated With Non–Vitamin‐K Oral Anticoagulants (RAF‐NOACs) Study – Journal of the American Heart Association (free)

“Composite rates of recurrence and major bleeding were 12.4% in patients who initiated NOACs within 2 days after acute stroke, 2.1% in those who initiated NOACs between 3 and 14 days, and 9.1% in patients who initiated NOACs >14 days after acute stroke. Future randomized studies to assess timing of initiation and choice of agent in patients with acute stroke and AF are warranted”.