Thu, February 15 – 10 Stories of The Day!

1 – Immunogenicity of Fractional-Dose Vaccine during a Yellow Fever Outbreak — Preliminary Report – The New England Journal of Medicine (free)

A fractional dose containing one fifth of the standard dose was effective at inducing seroconversion, supporting the use of fractional-dose vaccination for outbreak control.

2 – Evidence-based clinical practice guidelines for inflammatory bowel disease – Journal of Gastroenterology (free)

3 – Medical News & Perspectives: Do All Patients Need β-Blockers After a Heart Attack? – JAMA (free for a limited period)

4 – The state of OA: a large-scale analysis of the prevalence and impact of Open Access articles – PeerJ (free)

5 – Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free)

Commentary: New Guidelines for Treating Checkpoint Inhibitor Toxicities – Medscape (free registration required)

Relate guideline: Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free) AND Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)

6 – Uterine Neoplasms, Version 1.2018, NCCN Clinical Practice Guidelines in Oncology (free)

7 – New Dutch law to make all adults organ donors unless they opt out – CNN (free) AND Every Adult in This Country Is Now an Organ Donor Unless They Opt Out – TIME (free) AND Dutch law to make everyone organ donors unless they opt out – ABC News (free)

8 – Benefits and Harms of Cranial Electrical Stimulation for Chronic Painful Conditions, Depression, Anxiety, and Insomnia: A Systematic Review – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Mild shock therapy may ease anxiety and depression, but not chronic pain – Reuters (free) AND Jury Still Out on CES for Depression, Anxiety, Pain, Insomnia – Medscape (free registration required)

9 – Opioid Analgesic Use and Risk for Invasive Pneumococcal Diseases: A Nested Case–Control Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Opioids may be associated with increased risk for serious invasive pneumococcal infections – ACP Internist (free) AND Opioids For Pain Can Exacerbate Pneumococcal Infections – MedicalResearch.com (free) AND Prescription Opioid Use Tied to Higher Pneumonia Risk – MedPage Today (free registration required)

10 – Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study – The Lancet Infectious Diseases (free)

Commentaries: Surgical site infection—the next frontier in global surgery – The Lancet Infectious Diseases (free) AND Poor nations have higher risk of surgical infections, including resistant ones – CIDRAP (free)