Thu, April 19 – 10 Stories of The Day!
19 Apr, 2018 | 01:40h | UTC
Editorial: The Value in an Ambulatory Blood-Pressure Registry (free)
Commentaries: Value of Ambulatory BP Monitoring Bolstered by Large Study – TCTMD (free) AND 24-hour ambulatory BP measurements strongly predict mortality – The Hospitalist (free) AND Expert reaction to study looking at blood pressure measurement method and predicting risk of heart disease – Science Media Centre (free)
Editorial: Gene Therapy as a Curative Option for β-Thalassemia (free)
Quick Take Video Summary: LentiGlobin Gene Therapy for β-Thalassemia (free)
Commentaries: Gene therapy could free some people from a lifetime of blood transfusions – MIT Technology Review (free) AND Gene Therapy For Inherited Blood Disorder Reduced Transfusions – NPR (free) AND Expert reaction to study on gene therapy for beta-thalassaemia – Science Media Centre (free)
3 – A randomized trial of normothermic preservation in liver transplantation – Nature (free PDF for a limited period)
Commentaries: Room temperature liver storage technique improves transplant success – University of Oxford (free) AND Keeping livers ‘alive’ boosts transplant success, trial finds – BBC (free) AND A ‘breakthrough in organ preservation’: Study shows keeping livers warm helps preserve them for transplant – STAT (free)
4 – Viewpoint: Another Nail in the Coffin for Fish Oil Supplements – JAMA (free for a limited period)
5 – Time to challenge the spurious hierarchy of systematic over narrative reviews? – European Journal of Clinical Investigation (free) (via @kennylinafp and @Abraham_RMI)
Editorial: Closed loop systems in type 1 diabetes (free for a limited period)
7 – First-line drugs for hypertension – Cochrane Library (free)
Summary: Thiazides best first choice for hypertension – Cochrane Library (free)
“First-line low-dose thiazides reduced all morbidity and mortality outcomes in adult patients with moderate to severe primary hypertension. First-line ACE inhibitors and calcium channel blockers may be similarly effective, but the evidence was of lower quality”.
8 – Transradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in people with coronary artery disease – Cochrane Library (link to abstract – $ for full-text)
“Transradial approach for diagnostic coronary angiography or PCI (or both) in CAD may reduce short-term net adverse clinical events, cardiac death, all-cause mortality, bleeding, and access site complications”.
Related Guidelines: Clinical practice guidelines for the use of noninvasive positive-pressure ventilation and noninvasive continuous positive airway pressure in the acute care setting – Canadian Medical Association Journal (free) AND BTS/ICS guideline for the ventilatory management of acute hypercapnic respiratory failure in adults – Thorax (free)
Source: Critical Care Reviews Newsletter
10 – Association Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering: A Systematic Review and Meta-analysis – JAMA (link to abstract – $ for full-text)
Commentaries: Patients With Highest LDL Levels Benefit Most From Lipid-Lowering Drugs – MedicalResearch.com (free) AND New Study Finds that Statins Prevent Cardiovascular Deaths – Science Based Medicine (free) AND Meta-Analysis: ‘Floor’ for Lipid-Lowering Mortality Benefits May Be Real – MedPage Today (free registration required)
“In meta-analyses of LDL-C lowering drug trials, we found that total and cardiovascular mortality were reduced only when the mean baseline LDL-C in the trial was >100 mg/dl” (from MedicalResearch.com)