The Impact of Whole-Genome Sequencing on the Primary Care and Outcomes of Healthy Adult Patients

The Impact of Whole-Genome Sequencing on the Primary Care and Outcomes of Healthy Adult Patients: A Pilot Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

In healthy patients, genome sequencing raises alarms while offering few benefits – STAT News (free) AND Whole genome sequencing not ready for routine use: study – Reuters Health News (free) AND One in five ‘healthy’ adults may carry disease-related genetic mutations – Science (free) AND Whole-Genome Sequencing Possible in Clinic, but Value Unclear – Medscape (free registration required)

Whole-genome sequencing finds rare genetic disease risk in 1 of 5 healthy adults – ACP Internist Weekly (free)

“While some primary care physicians may be able to manage genomic information appropriately, findings could prompt increased health care use with limited clinical value, the researchers said” (from ACP)