Randomized Trial: Sodium Bicarbonate for Patients with Severe Metabolic Acidemia in the ICU
24 Jun, 2018 | 19:26h | UTCSodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: BICAR-ICU – The Bottom Line (free)
“This study will reassure clinicians that already use sodium bicarbonate for correcting metabolic acidaemia, that this may delay and/or reduce the requirement for RRT. Equally, for those that opt to avoid sodium bicarbonate, there is no compelling evidence to change practice”