Randomized Trial: Effects of Paracetamol + Ibuprofen vs Either Alone on Morphine Consumption After Total Hip Arthroplasty

Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentary: Ibuprofen may be a ‘reasonable option’ for analgesia after hip replacement – medwire News (free) AND Acetaminophen Plus Ibuprofen Linked to Less Morphine Use After Hip Arthroplasty – NEJM Journal Watch (free) AND Paracetamol plus ibuprofen significantly reduces post-operative morphine use in total hip arthroplasty patients – 2 Minute Medicine (free)