Opinion Piece Suggests Lack of Scientific Rigor in Study Extending the Time Window to IV TPA
13 May, 2019 | 01:21h | UTC“The Case of the Magician’s Sleight” – EMNerd (free)
See also: EXTEND Alteplase Shenanigans! – Emergency Medicine Literature of Note (free)
Original Study: Randomized Trial: Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke (link to abstract and commentary)
Related Cochrane Review: Thrombolysis for acute ischaemic stroke (free)
Related Review: Thrombolytics for stroke: The evidence – First10Em (free)
Related Commentary on Twitter
Using statistical magic to extend the time window for IV tPA by @EMNerd_ https://t.co/s0zgEdbs4x pic.twitter.com/ReHsFqTWWC
— the EMCrit Crew (@emcrit) May 10, 2019