Mon, October 9 – 10 Stories of The Day!

1 – Study links dental antibiotics to C diff cases – CIDRAP (free) AND Antibiotics for dental procedures linked to superbug infection – Infectious Diseases Society of America, via ScienceDaily (free)

Study Presented at #IDWeek2017

2 – Women who get frequent UTIs may reduce risk by drinking plenty of water – Infectious Diseases Society of America, via ScienceDaily (free) AND Recurrent Cystitis? Drink More Water – MedPage Today (free registration required) AND Drinking More Water Really Does Ward Off UTIs – LiveScience (free)

Study Presented at #IDWeek2017

3 – Efficacy and safety of switching from boosted protease inhibitors plus emtricitabine and tenofovir disoproxil fumarate regimens to single-tablet darunavir, cobicistat, emtricitabine, and tenofovir alafenamide at 48 weeks in adults with virologically suppressed HIV-1 (EMERALD): a phase 3, randomised, non-inferiority trial – The Lancet HIV (free)

Commentaries: Towards a universal second-line fixed-dose combination ART – The Lancet HIV (free) AND Single-Tablet ART: New Hope in HIV Therapy? All-in-one fixed dose combo proves safe, effective in EMERALD trial – MedPage Today (free registration required) AND EMERALD Trial: Week 48 Results Demonstrate Efficacy in Single-Tablet HIV Therapy – Infectious Diseases Advisor (free)

Study Presented at #IDWeek2017

4 – How Smartphones Hijack Our Minds – The Wall Street Journal (free) (RT @EricTopol see Tweet)

“Research suggests that as the brain grows dependent on phone technology, the intellect weakens”

5 – Impact of the Commercialization of Three Generic Angiotensin II Receptor Blockers on Adverse Events in Quebec, Canada: A Population-Based Time Series Analysis – Circulation: Cardiovascular Quality and Outcomes (free)

Commentaries: Generic Blood Pressure Drugs May Be Tied to Increase in Adverse Events – Physician’s First Watch (free) AND Generic ARBs Linked to Increased Adverse Events – TCTMD (free)

As in any observational study, association does not necessarily imply causation.

6 – Anticoagulant Use and Risk of Ischemic Stroke and Bleeding in Patients With Secondary Atrial Fibrillation Associated With Acute Coronary Syndromes, Acute Pulmonary Disease, or Sepsis – JACC: Clinical Electrophysiology (link to abstract – $ for full-text)

Commentaries: Anticoagulation didn’t benefit patients with afib secondary to ACS, pulmonary disease, or sepsis – ACP Hospitalist (free) AND No Anticoagulation Benefit, High Bleeding Risk Seen in Patients With Secondary A-fib – TCTMD (free)

7 – Serum Calcium and Risk of Sudden Cardiac Arrest in the General Population – Mayo Clinic Proceedings (link to abstract – $ for full-text)

Commentaries: Low serum calcium may increase risk of sudden cardiac arrest – EurekAlert (free) AND Low calcium may raise cardiac arrest risk by twofold – Medical News Today (free)

8 – Impact of the US Maternal Tetanus, Diphtheria, and Acellular Pertussis Vaccination Program on Preventing Pertussis in Infants <2 Months of Age: A Case-Control Evaluation – Clinical Infectious Diseases (link to abstract – $ for full-text)

Commentaries: Study: Tdap vaccine in pregnancy protects infants – CIDRAP (free) AND Fewer newborns get whooping cough when moms get vaccinated – Reuters (free)

9 – Pharmacologically controlled drinking in the treatment of alcohol dependence or alcohol use disorders: a systematic review with direct and network meta-analyses on nalmefene, naltrexone, acamprosate, baclofen and topiramate – Addiction (link to abstract – $ for full-text) checar acesso

Commentary: Pills prescribed for alcoholism might not work, study finds – The Guardian (free)

10 – ‘Antibiotic apocalypse’: doctors sound alarm over drug resistance – The Guardian (free)

Related WHO Reports: Antibacterial Agents in Clinical Development (free) AND Global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics (free) AND Commentary: WHO report paints dire picture of antibiotic development – CIDRAP (free)