Meta-Analysis: Proton Pump Inhibitors and Risk of Hip Fracture
7 Jan, 2019 | 19:35h | UTCProton pump inhibitors and risk of hip fracture: a meta-analysis of observational studies – Osteoporosis International (link to abstract – $ for full-text)
Commentary: PPIs up risk for hip fracture in large meta-analysis – Univadis (free registration required)
Related Commentary on Twitter
Metanalysis of 24 PPI studies, 319,568 hip fracture pts, suggests PPIs associated with a greater risk of hip fracture (RR 1.20, 95% CI 1.14–1.28, p < 0.0001) and may be greater with higher dose (RR 1.30, 95% CI 1.20–1.40, p < 0.0001). https://t.co/nbiEIPRaXg
— Dr. John Cush (@RheumNow) December 17, 2018