Meta-Analysis: Evaluation of the Association Between Gastric Acid Suppression and Risk of Intestinal Colonization with Multidrug-Resistant Microorganisms

Evaluation of the Association Between Gastric Acid Suppression and Risk of Intestinal Colonization With Multidrug-Resistant Microorganisms: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free)

Author Interview: Evaluation of Association Between Gastric Acid Suppression and Risk of Intestinal Colonization With MDROs – JAMA (free)

Commentary: Deprescribing Proton Pump Inhibitors: Overcoming Resistance – JAMA Internal Medicine (free for a limited period)

Related: Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing Proton Pump Inhibitors – Therapeutics Initiative (free)

Related Commentary on Twitter

NEW ?⚡systematic review& meta-analysis @JAMAInternalMed
The use of acid suppressants (mainly PPIs or H2RAs) associated w 75% ⬆️ odds of intestinal MDRO colonization,chiefly resistant Enterobacterales&VRE in the community&health care setting #IDTwitterhttps://t.co/ZKFtIYztqX pic.twitter.com/mLIuzM8V3p

— Antibiotic Steward ? (@ABsteward) February 24, 2020