Meta-Analysis: Dose Increase vs. Unchanged Continuation of Antidepressants After Initial Treatment Failure
21 May, 2018 | 13:11h | UTCDose Increase Versus Unchanged Continuation of Antidepressants After Initial Antidepressant Treatment Failure in Patients With Major Depressive Disorder: A Systematic Review and Meta-Analysis of Randomized, Double-Blind Trials – The Journal of Clinical Psychiatry (link to abstract – $ for full-text)
Commentary: Depression: boosting SSRIs doesn’t work – Univadis (free registration required)
“Meta-analysis: there is evidence from RCTs against increasing the dose of SSRIs (with the possible exception of citalopram) in adult patients with major depression and antidepressant treatment failure” (via @psychopharmacol see Tweet)