Fri, September 14 – 10 Stories of The Day!

1 – Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association – Hypertension (free PDF)

News Release: Diagnosing and treating resistant hypertension (free)

Commentaries: Tackling Resistant Hypertension – Opportunities and Challenges (free) AND Heart Group Updates Guidelines on Resistant Hypertension – Physician’s First Watch (free)

Top Ten Things to Know: Resistant Hypertension: Detection, Evaluation, and Management (free PDF)

2 – Elevated blood pressure and risk of aortic valve disease: a cohort analysis of 5.4 million UK adults – European Heart Journal (free)

Commentary: Elevated blood pressure is linked to increased risk of aortic valve disease – European Society of Cardiology (free)

3 – Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries – CA: A Cancer Journal for Clinicians (free)

See also: Latest global cancer data: Cancer burden rises to 18.1 million new cases and 9.6 million cancer deaths in 2018 – International Agency for Research on Cancer (free PDF)

Infographic: Global Cancer Data 2018 (free)

Commentaries: WHO: 9.6 million cancer deaths, 18 million new cases this year – UPI (free) AND Cancer will kill nearly 10 million people this year, report estimates – CNN (free) AND Cancer deaths rise to 9.6 million as populations grow and age – Reuters (free)

4 – Are Invasive Procedures Effective for Chronic Pain? A Systematic Review – Pain Medicine (free)

Commentaries: New study questions effectiveness of invasive procedures for chronic pain – The Reis Group (free) AND Invasive Procedures For Chronic Pain Have Not Been Proven to Work – MedicalResearch.com (free)

Related: Needless procedures: knee arthroscopy is one of the most common but least effective surgeries – The Conversation (free)

5 – What 21st Century Health Care Should Learn from 20th Century Business – NEJM Catalyst (free)

6 – The New ECG Apple Watch Could do More Harm Than Good – Wired (a few articles per month are free) (via @EricTopol)

See also: New Watch can Help Doctors Monitor your Heart in Real Time (free commentaries)

7 – Opinion: Scientific publishing is a rip-off. We fund the research – it should be free – The Guardian (free)

Related: cOAlition S: Making Open Access a Reality by 2020 (free Statement and commentaries)

8 – Thousands of scientists publish a paper every five days – Nature (free)

Related: Some scientists publish more than 70 papers a year. Here’s how—and why—they do it – Science (free)

9 – Effect of organised mammography screening on breast cancer mortality: A population‐based cohort study in Norway – International Journal of Cancer (free)

Commentaries: Breast cancer screening does not reduce mortality – eCancer News (free) AND Danish study attributes improved treatment, not screening, to decline in breast cancer deaths – Health Imaging (free)

10 – Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis – JAMA Oncology (free for a limited period)

Commentaries: Study Discerns Rare Risks of Fatal Side Effects From Cancer Immunotherapy – AJMC (free) AND Fatal Toxicities Rare With Checkpoint Inhibitors – MedicalResearch.com (free)

Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)

Related Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)