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Fri, October 5 – 10 Stories of The Day!

5 Oct, 2018 | 00:01h | UTC

 

1 – Acceleration of BMI in Early Childhood and Risk of Sustained Obesity – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Childhood BMI Acceleration and Sustained Obesity (free)

Commentary: BMI in Early Childhood and Sustained Obesity – American College of Cardiology (free)

 

2 – Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentaries: The Lancet Diabetes & Endocrinology: Vitamin D supplementation in adults does not prevent fractures, falls or improve bone mineral density – The Lancet (free) AND Vitamin D supplements don’t help bone health, major study concludes – The Guardian (free) AND Millions of Americans take vitamin D. Most should just stop – VOX (free)

Related: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It (free commentaries and NICE Guideline) AND Vitamin D Not Linked to Fracture Risk (free study and commentaries)

 

3 – Clinical Update: Immune Checkpoint Inhibitor Toxicity in 2018 – JAMA (free for a limited period)

Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)

Related Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)

 

4 – Perspective: Given Their Potential for Harm, It’s Time to Focus on the Safety of Supplements – JAMA (free) (via @NUNESDOC)

“About 23 000 visits to emergency departments each year can be attributed to adverse events from dietary supplements.”

 

5 – Perspective: When Conventional Wisdom Is Put on Trial – UNDark (free) (via @EricTopol)

“The author of “Randomistas” shows how randomized trials have overturned many popular findings, from hormone therapy to the benefits of multivitamins.”

 

6 – Report: The future of healthcare – The Economist (free PDF)

 

7 – Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Weight loss drug shows positive effect on diabetes – Brigham and Women’s Hospital (free) AND Weight Loss Drug Helped Prevent Diabetes in Overweight People – MedPage Today (free registration required)

Related Article: Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients (link to abstract and commentaries)

 

8 – Collaboration between academics and industry in clinical trials: cross sectional study of publications and survey of lead academic authors – The BMJ (free)

Commentaries: Shining a light on industry collaboration – The BMJ Opinion (free) AND Industry funders involved in most aspects of funded trials – OnMedica (free)

 

9 – Perspective: New Tools in the Ebola Arsenal – New England Journal of Medicine (free)

Related: DRC Ebola cases rise as security concerns continue – CIDRAP (free) AND Officials fear Ebola epidemic may be spinning beyond their control, threatening regional spread – STAT (free) AND Ebola Likely to Spread From Congo to Uganda, W.H.O. Says – The New York Times (10 articles per month are free)

 

10 – Prescribed Exercise With Compression vs Compression Alone in Treating Patients With Venous Leg Ulcers: A Systematic Review and Meta-analysis – JAMA Dermatology (link to abstract – $ for full-text)

Commentaries: Adding Exercise to Compression Improves Outcomes in Venous Leg Ulcers – Physcian’s First Watch (free) AND Compressions May Remedy Venous Leg Ulcers – MedPage Today (free)

 


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