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Fri, July 20 – 10 Stories of The Day!

20 Jul, 2018 | 01:07h | UTC

 

1 – Expert reaction to trial looking at adrenaline for cardiac arrests – Science Media Centre (free)

See original article in yesterday’s issue: A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest (see #1)

Related Review: The role of adrenaline in cardiopulmonary resuscitation – Critical Care (free)

 

2 – A Phase 3 Trial of l-Glutamine in Sickle Cell Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Glutamine to Treat Sickle Cell Disease (free)

Commentary: Drug may ease pain, lessen hospitalization from sickle cell disease – UPI (free)

 

3 – Subacromial decompression versus diagnostic arthroscopy for shoulder impingement: randomised, placebo surgery controlled clinical trial – The BMJ (free)

Commentary: Most common shoulder operation is no more beneficial than placebo surgery – University of Helsinki, via EurekAlert (free)

Related research with similar results: Arthroscopic subacromial decompression for subacromial shoulder pain (free article, editorial and commentaries)

 

4 – Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study – The BMJ (free)

Commentaries: A Spike In Liver Disease Deaths Among Young Adults Fueled By Alcohol – NPR (free) AND Alcohol-related liver failure deaths rising among U.S. young adults – Reuters (free) AND More Americans Are Dying of Cirrhosis and Liver Cancer – The New York Times (10 articles per month are free)

 

5 – Complementary Medicine, Refusal of Conventional Cancer Therapy, and Survival Among Patients With Curable Cancers – JAMA Oncology (free for a limited period)

Commentary: Association of complementary medicine, cancer treatment, survival – eCancer News (free)

 

6 – Clinical Evidence Synopsis: Probiotics to Prevent Clostridium difficile Infection in Patients Receiving Antibiotics – JAMA (free for a limited period)

Original Article: Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children – Cochrane Library (link to abstract – $ for full-text) AND Summary: The use of probiotics to prevent Clostridium difficile diarrhea associated with antibiotic use (free)

Related Meta-Analysis: Timely Use of Probiotics in Hospitalized Adults Prevents Clostridium difficile Infection (free) AND Probiotics for the Prevention of Clostridium difficile (link to abstract and commentaries)

 

7 – To continue taking or to stop taking antiplatelet drugs for a few days before non-cardiac surgery in adults – Cochrane Library (link to abstract – $ for full-text)

Summary: To continue taking or to stop taking antiplatelet drugs for a few days before non-cardiac surgery in adults – Cochrane Library (free)

We found low-certainty evidence that either continuation or discontinuation of antiplatelet therapy before non-cardiac surgery may make little or no difference to mortality, bleeding requiring surgical intervention, or ischaemic events”.

 

8 – Effects of Leisure‐Time and Transport‐Related Physical Activities on the Risk of Incident and Recurrent Myocardial Infarction and Interaction With Traffic‐Related Air Pollution: A Cohort Study – Journal of the American Heart Association (free)

Commentaries: Poor air quality does not offset exercise’s heart benefits – AHA/ASA Newsroom (free) AND Why smog should not be your excuse to skip workouts – Reuters (free)

 

9 – Metformin and Risk of Hypertension in Taiwanese Patients With Type 2 Diabetes Mellitus – Journal of the American Heart Association (free)

“A reduced risk of hypertension is observed in metformin users in a dose‐response pattern”.

 

10 – Sulfonylureas as second line drugs in type 2 diabetes and the risk of cardiovascular and hypoglycaemic events: population based cohort study – The BMJ (free)

Editorial: Sulfonylureas as second line treatment for type 2 diabetes – The BMJ (free for a limited period)

Commentaries: Diabetes: Switching to Sulfonylureas from Metformin Linked to Increased Side Effects – MedicalResearch.com (free) AND Switching diabetes patients to sulfonylurea linked with complications – Pulse (free) AND Raised risk of MI and mortality when starting sulfonylurea – OnMedica (free)

 


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