[Abstract Only] Open-Label Randomized Trial: Oseltamivir vs. Usual Care for Influenza-like Illness in Primary Care

Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentaries (with conflicting opinions): Tamiflu, Cure-All – Emergency Literature of Note (free) AND Flu antiviral has bigger benefits for sicker, older patients – University of Oxford (free)

Related Systematic Reviews: Neuraminidase inhibitors for preventing and treating influenza in adults and children – Cochrane Library (free) AND Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments – The BMJ (free) AND Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials – The Lancet (free registration required) AND Effectiveness of oseltamivir in adults: a meta-analysis of published and unpublished clinical trials – Family Practice (free)

Related Commentary on Twitter

New paper published in the Lancet found a moderate improvement in symptoms in pts treated with open label oseltamivir compared to usual care. Any one else find it curious it worked equally well in pts with and without confirmed influenza? https://t.co/KpBM1xMOTu pic.twitter.com/GcGi4yFBVO

— Rory Spiegel (@EMNerd_) January 3, 2020