1 – Defining Optimal Brain Health in Adults: A Presidential Advisory From the American Heart Association/American Stroke Association (free)

See also: Advisory Highlights: Seven steps to keep your brain healthy from childhood to old age (free) AND News release: As brain problems increase, experts offer advice to keep yours healthy (free) AND Commentary: Optimal Cardiovascular Health and a Healthy Brain (free) AND Top Ten Things to Know: Defining Optimal Brain Health in Adults (free PDF)

Commentary: Heart and Stroke Groups Issue Advisory on Optimal Brain Health – Physician’s First Watch (free)

  

2 – Everybody active, every day: an evidence-based approach to physical activity – Public Health England (free report and other documents)

See also: 10 minutes brisk walking each day in mid-life for health benefits and towards achieving physical activity recommendations: evidence summary (free PDF)

Press release: 6 million adults do not do a monthly brisk 10-minute walk (free)

Commentaries: 10-minute walk a day app to tackle ‘inactivity epidemic’ – NHS Choices (free) AND 6 million middle-aged people take no exercise – The Guardian (free)

 

3 – Report: Size matters: The impact of upselling on weight gain – Royal Society for Public Health; Slimming World (free PDF)

See also: Press release (free)

Commentaries: Supersize us: upselling is fuelling the obesity epidemic, warns report – The Guardian (free) AND Going Large – Is Upselling Making You Gain Weight? – Medscape (free registration required)

 

4 – Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies – European Heart Journal (free)

Commentaries: High levels of ‘good’ cholesterol linked to excessive mortality – University of Copenhagen, via ScienceDaily (free) AND Does ‘good cholesterol’ really deserve its name? – The Conversation (free) AND Can Your “Good” Cholesteral Be To High? – The New York Times (10 articles per month are free)

 

5 – Antipsychotic Use With and Without Comorbid Psychiatric Diagnosis Among Adults with Intellectual and Developmental Disabilities – The Canadian Journal of Psychiatry (link to abstract – $ for full-text)

Commentaries: Antipsychotics common for adults with intellectual and developmental disabilities – Centre for Addiction and Mental Health (free) AND Antipsychotics Overused in Intellectually Disabled Adults – Medscape (free registration required)

“Antipsychotics are used inappropriately particularly in vulnerable groups: Poor children; Intellectually challenged; Autistic; Nursing homes. (RT @AllenFrancesMD see Tweet)

 

6 – Safety and Feasibility of Antiretroviral Preexposure Prophylaxis for Adolescent Men Who Have Sex With Men Aged 15 to 17 Years in the United States – JAMA Pediatrics (free)

Editorial: Human Immunodeficiency Virus Preexposure Prophylaxis for Adolescent Men (free)

Commentaries: Safety, Feasibility of PrEP for Adolescent Men Who Have Sex With Men – The JAMA Network (free) AND PrEP safe and effective for young men who have sex with men – OnMedica (free) AND HIV PrEP for adolescent men found to be safe, effective – UPI (free)

 

7 – Potential Implications of NORSTENT (Norwegian Coronary Stent Trial) in Contemporary Practice – Circulation (free)

Original article: Drug-Eluting or Bare-Metal Stents for Coronary Artery Disease – New England Journal of Medicine (free)

In this large trial, differences in outcomes between bare metal stents (BMS) and drug eluding stents (DES) were small. During 6 years of follow-up there was a 3.3% absolute risk reduction in any repeat revascularization with DES, without differences in cardiovascular mortality or death.

 

8 – Chronic Health Conditions and Key Health Indicators Among Lesbian, Gay, and Bisexual Older US Adults, 2013–2014 – American Journal of Public Health (link to abstract – $ for full-text)

Commentaries: Lesbian, Gay and Bisexual Older Adults Suffer More Chronic Health Conditions Than Heterosexuals, Study Finds – The University of Washington, via NewsWise (free) AND LGB Older Adults Suffer More Chronic Health Conditions Than Heterosexuals, Study Finds – Science Magazine (free)

 

9 – IBM pitched its Watson supercomputer as a revolution in cancer care. It’s nowhere close – STAT (free)

 

10 – Intravenous Versus Nonintravenous Benzodiazepines for the Cessation of Seizures: A Systematic Review and Meta-analysis of Randomized Controlled Trials – Academic Emergency Medicine (link to abstract – $ for full-text)

Source: Hospital Medicine Virtual Journal Club

 “Should you give your preferred benzo by the fastest means possible? Or establish an IV and administer via that route? The short answer provided by this study, is to give your benzo IM or IN. While seizures stopped sooner after IV administration, the additional time needed to establish an IV resulted in overall longer seizure time when administered via that method” (by Jeremy Fried in Research and Reviews in the Fastlane 182).

 

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