Mon, May 22 – 10 Medical Stories of The Day!

1 – Time to Treatment and Mortality during Mandated Emergency Care for Sepsis – New England Journal of Medicine (free)

Commentary: Doctors have resisted guidelines to treat sepsis. New study suggests those guidelines save lives – STAT News (free)

“For every hour you delay antibiotics in sepsis, mortality goes up” (RT @CMichaelGibson see Tweet)

“Trauma: Golden Hour

Cardiology: Time is muscle

Neurology: Time is brain

Sepsis: Early antibiotics to survive”

(interesting remark by @CMichaelGibson see Tweet)

2 – Italy makes 12 vaccinations compulsory for children – BBC Health News (free) AND Italy passes law obliging parents to vaccinate children – Reuters Health (free)

Related: Embrace the facts about vaccines, not the myths – World Health Organization (free) AND World Immunisation Week: The Rise of Anti-Vaccine Movement and What it Means for Public Health – Independent (free) AND The riskiest vaccine? The one that is not given – Science (free)

“If children are not vaccinated by the age of six, the school starting age, their parents will be fined” (RT @anetrid see Tweet)

3 – Science Has Begun Taking Gluten Seriously – The Atlantic (free)

Original article: Long term gluten consumption in adults without celiac disease and risk of coronary heart disease: prospective cohort study – The BMJ (free)

“New research from Harvard and Columbia says gluten does not cause heart disease. Why is that even a question?”

4 – The effect of replacing saturated fat with mostly n-6 polyunsaturated fat on coronary heart disease: a meta-analysis of randomised controlled trials – Nutrition Journal (free)

There has been a lot of controversy going on over the benefits and harms of saturated fats (April 27^th issue, see #3) and it is difficult to interpret this new meta-analysis from randomized trials suggesting there may be no benefit from replacing saturated fats for unsaturated fats, since they contradict current guidelines and most epidemiological data from high-quality, long-term prospective cohort studies.

5 – Report: Healthier, fairer, safer: the global health journey 2007–2017 (free)

“New report on WHO’s role in Global Health by Sir Liam Donaldson” (RT @WHO see Tweet)

6 – Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990–2015: a novel analysis from the Global Burden of Disease Study 2015 – The Lancet (free)

Commentaries: First-ever global study finds massive health care inequity – Institute for Health Metrics and Evaluatio (IHME) (free) AND Account for primary health care when indexing access and quality – The Lancet (free)

7 – Without action on antibiotics, medicine will return to the dark ages – The Guardian (free)

See more on “superbugs” in our February 28^th issue (see #1), April 6^th issue (see #9) and also in our Selection of news and education resources on Antibiotic Resistance

8 – Finally, Success Reducing Recurrent Stroke With PFO Closure – Medscape (free registration required)

Two randomized trials presented at the 3rd European Stroke Organization Conference (ESOC) 2017 showed that in carefully selected stroke patients in whom Patent Foramen Oval (PFO) was suspected to be a cause of their strokes, a reduction in recurrent stroke was observed with PFO closure.

9 – Report: #StatusOfMind Social media and young people’s mental health and wellbeing – Royal Society of Public Health (link to introduction – free PDF)

Commentaries: Instagram ‘worst for young mental health’ – BBC News (free) AND Instagram worst social media app for young people’s mental health – CNN news (free)

10 – Point of view: Is ‘Internet Addiction’ Real? – NPR Health News (free)