Fri, May 19 – 10 Medical Stories of The Day!

1 – Joint statement on public disclosure of results from clinical trials – World Health Organization (free)

News release: Major research funders and international NGOs to implement WHO standards on reporting clinical trial results (free)

Commentary: Industry leaders agree to implement UN agency’s standards on clinical trial reporting – United Nations News Centre (free)

“Funders of medical research & international NGOs to implement WHO standards on reporting clinical trial results”. “Today, on average 50% of Clinical Trials go unreported, according to several studies, often because the results are negative”. “Unreported trial results leave an incomplete & potentially misleading picture of the risks & benefits of vaccines, drugs and medical devices” (see Tweets)

2 – Health and Public Policy to Facilitate Effective Prevention and Treatment of Substance Use Disorders Involving Illicit and Prescription Drugs: An American College of Physicians Position Paper – Annals of Internal Medicine (free)

News release: ACP issues recommendations to prevent and treat substance use disorders (free)

Commentary: Treat Addiction Like a Chronic Disease, ACP Recommends – AJMC (free)

3 – Viewpoint: Primary Care of Patients with Chronic Pain – JAMA (free)

“Opioids should be a therapy of last resort rather than the first choice as is often the case currently”.

4 – Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)

Commentary: New Guideline Recommends Opioids Only as a Last Resort – Medscape (free registration required)

5 – The Best Intervention: Gavi CEO Seth Berkley’s Q&A, Part I – Global Health NOW (free)

“Perhaps just 10% of the world’s children receive all 11 vaccines recommended by the @WHO, says @GaviSeth, @Gavi CEO” (RT @ghn_news see Tweet)

6 – Tackling Ebola outbreak in remote Congo presents huge challenge: WHO – Reuters Health (free)

Related: As DRC Ebola cases grow, expert sees parallels to Guinea – CIDRAP (free) As Ebola outbreak grows, question of using vaccine becomes more urgent – Science (free) (RT @greg_folkers) AND Suspected Cases of Ebola Rise to 18 in Democratic Republic of Congo – The New York Times (10 articles per month are free)

7 – New Advice to Move More After a Concussion – The New York Times (10 articles per month are free)

Related: Consensus statement on concussion in sport—the 5^th international conference on concussion in sport held in Berlin, October 2016 – British Journal of Sports Medicine (free) AND So, Tom Brady had a concussion. What does that mean? Your guide to the latest science – STAT News (free)

8 – Pressure ulcer prevention and treatment. Is ‘best practice’ evidence-based? – Cochrane Blogs: Evidence for Everyday Nursing (free) (RT @CochraneUK see Tweet)

Evidence for the treatment of pressure ulcers reviewed.

9 – Aerobic or Resistance Exercise, or Both, in Dieting Obese Older Adults – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Exercise and Dieting in Obese Older Adults (free)

Commentary: Aerobic Plus Resistance Exercise Best for Obese Older Adults – MedPage Today (free)

10 – Long-term oxygen therapy shows no benefit for moderate lung disease – NIHR Signal: Dissemination Centre Discover Portal (free)

Original article: A Randomized Trial of Long-Term Oxygen for COPD with Moderate Desaturation – New England Journal of Medicine (free)

Patients with stable COPD and moderate resting desaturation (Spo₂, 89 to 93%) or moderate exercise-induced desaturation (during the 6-minute walk test, Spo₂ ≥80% for ≥5 minutes and <90% for ≥10 seconds) don’t seem to benefit from supplemental oxygen therapy.