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1 – Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial – The Lancet (free)

Editorial: WOMAN: reducing maternal deaths with tranexamic acid (free)

Commentary: Overlooked Drug Could Save Thousands Of Moms After Childbirth – NPR Goats and Soda (free)

“Tranexamic acid reduced deaths of mothers caused by bleeding after childbirth by 1/3” (RT @LSHTMpress see Tweet)


2 – Guideline: Role of Biomarkers for the Prevention, Assessment, and Management of Heart Failure: A Scientific Statement From the American Heart Association (free PDF)

News release: New guidance on heart failure tests can improve care – American Heart Association News (free)


3 – Editorial: Saturated fat does not clog the arteries: coronary heart disease is a chronic inflammatory condition, the risk of which can be effectively reduced from healthy lifestyle interventions – British Journal of Sports Medicine (free)

Commentaries on the editorial: Does saturated fats clog your arteries? Controversial paper says ‘no’ – CNN (free) AND The Battle Over the Causes of Cardiovascular Disease Heats Up! – By George Henderson and Grant Schofield (free) AND Backlash after report claims saturated fats do not increase heart risk – The Guardian (free) AND Expert reaction to editorial on saturated fat and heart disease – Science Media Centre (free)

Fat wars continue. New interesting but controversial editorial heats up the debate.


4 – Guidelines For Management Of Dyslipidemia And Prevention Of Cardiovascular Disease – American Association Of Clinical Endocrinologists And American College Of Endocrinology (free PDF) (RT @greg_folkers)


5 – Adherence to High-Intensity Statins Following a Myocardial Infarction Hospitalization Among Medicare Beneficiaries – JAMA Cardiology (link to abstract – $ for full-text)

Source: Heart Attack Survivors Often Fail to Take Statins – The New York Times (free)

In this cohort only 41.6% of patients aged 66 to 75 years continued taking statins as prescribed at 2 years.


6 – Five years wisely: A look at Choosing Wisely’s effort to reduce unnecessary medical care – HealthNewsReview (free) (RT @pash22 and @glassmanamanda see Tweet)

See also: Choosing Wisely initiative was launched 5 years ago in our April 5 issue.


7 – How to Fight Cancer (When Cancer Fights Back) – The Atlantic (free)

“Understanding how the disease evolves is the key to stopping it”.


8 – How hype can mislead cancer patients, families – CNN (free)

Related: Financial toxicity: 1 in 3 cancer patients have to turn to friends or family to pay for care – STAT News (free) AND Not Just Nausea And Vomiting: Cancer Docs Now Worry About ‘Financial Toxicity’ – WBUR (free)

“Cancer cost crisis forces tough choices”.


9 – Alcohol consumption, sinus tachycardia, and cardiac arrhythmias at the Munich Octoberfest: results from the Munich Beer Related Electrocardiogram Workup Study (MunichBREW) – European Heart Journal (free)

Sources: Alcohol binge can upset heart’s rhythm, say researchers – BBC Health News (free) AND Binge Drinkers Beware: Study Finds Link Between Alcohol And Heart Arrhythmias – NPR (free) AND Oktoberfest: Downing Beers, Raising Heart Rates – Acute measurement in beer tents shows high rate of sinus tachycardia – MedPage Today (free registration required)


10 – After Knee or Hip Replacement, No Place Like Home – The New York Times (10 articles per month are free)

See also: Time to Rethink Inpatient Rehab After Knee Replacement? – The Rheumatologist (free)

Original article abstract ($ for full-text): Effect of Inpatient Rehabilitation vs a Monitored Home-Based Program on Mobility in Patients With Total Knee Arthroplasty: The HIHO Randomized Clinical Trial – JAMA (free)

The NYT commentary talks about the futility of some interventions currently used to postpone surgery and about the benefits of outpatient rehabilitation.


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