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Daily Archives: September 27, 2018

Study: Recovery of Walking after Complete Spinal Cord Injury

27 Sep, 2018 | 23:06h | UTC

Recovery of Over-Ground Walking after Chronic Motor Complete Spinal Cord Injury – New England Journal of Medicine (free)

Commentaries: Technology and therapy help individuals with chronic spinal cord injuries take steps – University of Louisville (free) AND Epidural Stimulation Helps Patients Walk After Total Paralysis – MedPage Today (free registration required) AND Paralyzed Patients Able to Walk Following Epidural Stimulation, Intense Rehab – Physician’s First Watch (free)

 


Study: Deep Learning Algorithm for Detection of Malignant Pulmonary Nodules on Chest Radiographs

27 Sep, 2018 | 23:04h | UTC

Development and Validation of Deep Learning–based Automatic Detection Algorithm for Malignant Pulmonary Nodules on Chest Radiographs – Radiology (link to abstract – $ for full-text)

Commentary: Deep learning algorithm detects malignant pulmonary nodules better than radiologists – Radiology Business (free)

Related Studies: Deep Learning for the Diagnosis of Fibrotic Lung Disease (link to abstract and commentaries) AND Can Artificial Intelligence Reliably Report Chest X-Rays? (free study and commentaries) AND Artificial Intelligence Can Determine Lung Cancer Type (link to abstract and commentaries)

 


Study: Drug–herb and Drug–supplement Interactions in Older Adults

27 Sep, 2018 | 23:05h | UTC

Prevalence of drug–herb and drug–supplement interactions in older adults: a cross-sectional survey – British Journal of General Practice (free)

Commentaries: New study finds concurrent use of prescription drugs and dietary supplements could pose health risks – University of Hertfordshire (free) AND Concerns raised about older adults mixing prescription drugs and herbal remedies – NHS Choices (free)

 


Measuring Human Capital: A Systematic Analysis of 195 Countries and Territories, 1990–2016

27 Sep, 2018 | 23:03h | UTC

Measuring human capital: a systematic analysis of 195 countries and territories, 1990–2016 – The Lancet (free)

Commentary: Unprecedented study finds nations failing to invest in education and health care at risk of slow economic growth – Institute for Health Metrics and Evaluation (free)

Infographic: What is human capital and why is it relevant? – Institute for Health Metrics and Evaluation (free)

“The first-ever study ranking countries by human capital has been published in @TheLancet. This novel approach looks at nations’ investments in health and education and their relation to GDP growth” (via @IHME_UW see Tweet)

 


Review: Pharmacokinetics–Pharmacodynamics Issues Relevant for the Clinical use of Beta-lactams in Critically Ill Patients

27 Sep, 2018 | 23:02h | UTC

Pharmacokinetics–pharmacodynamics issues relevant for the clinical use of beta-lactam antibiotics in critically ill patients – Critical Care (free)

Related: Extended Antibiotic Infusions Could Save Lives: Here’s How to Do It (free commentary) AND Mortality lower with prolonged vs. short-term IV infusion of antipseudomonal beta-lactams (link to abstract and free commentary)

 


Study: Adverse Outcomes After Arthroscopic Partial Meniscectomy

27 Sep, 2018 | 22:59h | UTC

Adverse outcomes after arthroscopic partial meniscectomy: a study of 700 000 procedures in the national Hospital Episode Statistics database for England – The Lancet (free)

Invited Commentary: Potential harms of isolated arthroscopic partial meniscectomy (free)

Related: Needless procedures: knee arthroscopy is one of the most common but least effective surgeries – The Conversation (free) AND Arthroscopic surgery for degenerative knee arthritis and meniscal tears: a clinical practice guideline (free guideline and commentary)

 


Randomized Trial: Algorithm-Based Therapy vs Usual Care in Patients with Staphylococcal Bacteremia

27 Sep, 2018 | 22:58h | UTC

Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Treatment Algorithms for Staphylococcal Bacteremia: Improving Clinical Care and Enhancing Antimicrobial Stewardship (free for a limited period)

Commentary: Algorithm may reduce antibiotics for staph bloodstream infections – CIDRAP (free)

 


Ebola Response Faces ‘Grave Obstacles’ as Count Hits 150

27 Sep, 2018 | 23:01h | UTC

Ebola response faces ‘grave obstacles’ as count hits 150 – CIDRAP (free)

Related: WHO warns of ‘perfect storm’ for Ebola in eastern Congo – STAT (free) AND WHO extremely concerned about Ebola ‘perfect storm’ in Congo – Reuters (free)

 


Randomized Trial: Transcatheter Mitral-Valve Repair in Patients with Heart Failure

27 Sep, 2018 | 22:56h | UTC

Transcatheter Mitral-Valve Repair in Patients with Heart Failure – New England Journal of Medicine (free)

Commentary: COAPT: MitraClip Reduces Repeat Hospitalizations, Mortality in Functional MR Patients With Severe HF – TCTMD (free)

Related MITRA-FR trial: Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation – New England Journal of Medicine (free)

“Physicians responded with shock and excitement to findings, but struggled to reconcile the results with the MITRA-FR trial.” (from TCTMD)

 


Report: Noncommunicable Diseases Country Profiles 2018

27 Sep, 2018 | 22:57h | UTC

Noncommunicable Diseases Country Profiles 2018 – World Health Organization (free PDF)

See also: NCDs profile by country (free)

 


Review: Streptococcal Toxic Shock Syndrome in the Intensive Care Unit

27 Sep, 2018 | 22:46h | UTC

Streptococcal toxic shock syndrome in the intensive care unit – Annals of Intensive Care (free)

Source: Critical Care Reviews Newsletter

 


Study: Benefit of Anticoagulation for Stroke Prevention May Vary in Patients with Atrial Fibrillation

27 Sep, 2018 | 22:56h | UTC

Effect of Variation in Published Stroke Rates on the Net Clinical Benefit of Anticoagulation for Atrial Fibrillation – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Benefit of anticoagulation for stroke prevention may vary in patients with afib, study finds – ACP Internist (free)

 


Consensus: Targeted Temperature Management in Patients with Intracerebral Hemorrhage, Subarachnoid Hemorrhage, or Acute Ischemic Stroke

27 Sep, 2018 | 22:46h | UTC

Targeted temperature management in patients with intracerebral haemorrhage, subarachnoid haemorrhage, or acute ischaemic stroke: consensus recommendations – British Journal of Anaesthesia (free)

Source: Critical Care Reviews Newsletter

 


Ann Robinson’s research reviews – 24 September 2018

27 Sep, 2018 | 22:43h | UTC

Ann Robinson’s research reviews, 24 September 2018 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Podcast: Geriatric Depression

27 Sep, 2018 | 22:45h | UTC

#115 Geriatric Depression – The Curbsiders Internal Medicine Podcast (free)

Summary: #115 Geriatric Depression: Diagnosis, Antidepressants, and More (free)

 


Free Online Course: Antibiotic Stewardship

27 Sep, 2018 | 22:42h | UTC

Free Online Course: Antibiotic Stewardship – Stanford University and Coursera (via @classcentral)

 


NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk

27 Sep, 2018 | 22:41h | UTC

Double check patients with ‘penicillin allergy’ to avoid increased MRSA risk – NICE News and Features (free)

Related Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy (free article and commentaries)

 


Congratulations. Your Study Went Nowhere

27 Sep, 2018 | 22:42h | UTC

Congratulations. Your Study Went Nowhere – The New York Times (10 articles per month are free) (via @kennylinafp)

“Researchers should embrace negative results instead of accentuating the positive, which is one of several biases that can lead to bad science.”

 


WHO Global Status Report on Alcohol and Health 2018

27 Sep, 2018 | 22:40h | UTC

Global status report on alcohol and health 2018 – World Health Organization (free PDF)

News Release: Harmful use of alcohol kills more than 3 million people each year, most of them men (free)

Commentaries: Alcohol abuse kills 3 million a year, most of them men: WHO – Reuters (free) AND 1 in 20 deaths globally is a result of alcohol use – CNN (free) AND Alcohol causes one in 20 deaths worldwide, says WHO – The Guardian (free)

 


Clinical Update: Management of Chronic Wounds

27 Sep, 2018 | 22:36h | UTC

Management of Chronic Wounds—2018 – JAMA (free for a limited period)

 


NCD Countdown 2030: Worldwide Trends in Non-communicable Disease Mortality and Progress Towards the SDGs

27 Sep, 2018 | 22:39h | UTC

NCD Countdown 2030: worldwide trends in non-communicable disease mortality and progress towards Sustainable Development Goal target 3.4 – The Lancet (free registration required)

Commentaries: Most nations falling short of targets to cut early deaths from chronic disease – Imperial College London (free) AND New Data Suggest More Than Half of Countries Not on Track to Meet Global NCD Goals – American College of Cardiology (free) AND Globally, losing the fight against cancer and other chronic diseases – CNN (free)

 


Study: Immediate Compression Could Help Prevent Complications after DVT

27 Sep, 2018 | 22:39h | UTC

Residual vein occlusion in relation to immediate compression and postthrombotic syndrome in deep vein thrombosis – Blood (free PDF)

Commentary: Immediate compression could help prevent complications after deep-vein thrombosis – American Society of Hematology (free)

“Study supports use of this simple, low-cost intervention even for patients without symptoms” (from American Society of Hematology)

 


Review: Diagnostic Testing for Elevated Cortisol in the Setting of an Adrenal Mass

27 Sep, 2018 | 22:35h | UTC

Diagnostic Testing for Elevated Cortisol in the Setting of an Adrenal Mass – JAMA (free for a limited period)

 


Perspective: Amazing Ways Artificial Intelligence is Used in Healthcare

27 Sep, 2018 | 22:33h | UTC

Amazing ways artificial intelligence is used in healthcare – World Economic Forum (free)

 


‘Latent’ Tuberculosis? It’s Not That Common, Experts Find

27 Sep, 2018 | 22:35h | UTC

‘Latent’ Tuberculosis? It’s Not That Common, Experts Find – The New York Times (1o articles per month are free)

Related Analysis: Revisiting the timetable of tuberculosis – The BMJ (free analysis and commentary)

 


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