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Daily Archives: July 13, 2018

WHO Campaign: Seven Strategies for Ending Violence Against Children

13 Jul, 2018 | 03:05h | UTC

INSPIRE: Seven strategies for ending violence against children – World Health Organization (free resources)

Fact Sheet: Violence against children – World Health Organization (free)

The package includes the core document describing what the INSPIRE strategies and interventions are; an implementation handbook that provides details on how to implement the interventions, and a set of indicators to measure the uptake of INSPIRE and its impact on levels of violence against children.

 


Study: Safety Planning Intervention With Follow-up vs Usual Care of Suicidal Patients

13 Jul, 2018 | 03:05h | UTC

Comparison of the Safety Planning Intervention With Follow-up vs Usual Care of Suicidal Patients Treated in the Emergency Department – JAMA Psychiatry (free for a limited period)

Author Interview: Association of Safety Planning Intervention With Subsequent Suicidal Behavior Among ER-Treated Suicidal Patients (free)

Commentaries: ED Intervention with Follow-Up Appears to Reduce Suicidal Behaviors – NEJM Physician’s First Watch (free) AND A Simple Emergency Room Intervention Can Help Cut Suicide Risk – NPR (free)

Related Studies: Suicide Prevention in an Emergency Department Population (free study and commentaries) AND Strategies to prevent death by suicide (link to abstract and commentaries)

 


Study: Bleeding Risk with Concomitant NSAIDs and Anticoagulants in Atrial Fibrillation

13 Jul, 2018 | 03:04h | UTC

Concomitant Oral Anticoagulant and Nonsteroidal Anti-Inflammatory Drug Therapy in Patients With Atrial Fibrillation – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Bleeding Risk Increased With NSAID Use in Anticoagulated A-fib Patients: RE-LY Analysis – TCTMD (free) AND NSAID, anticoagulant combo ups risk for bleeding events in AFib patients – Cardiovascular Business (free) Concomitant NSAIDs and Anticoagulants in Atrial Fibrillation – American College of Cardiology (free)

 


Infographic: Testing for Non-alcoholic Fatty Liver Disease

13 Jul, 2018 | 03:03h | UTC

Testing for non-alcoholic fatty liver disease -The BMJ (free PDF)

 


Last Month in Oncology with Dr. Bishal Gyawali

13 Jul, 2018 | 03:01h | UTC

Last Month in Oncology with Dr. Bishal Gyawali: June 2018 – eCancer News (free)

This review has an interesting opinion on changing definitions of clinically meaningful endpoints in cancer research.

 


Report: Research Into Physiotherapy for Musculoskeletal Conditions

13 Jul, 2018 | 03:01h | UTC

Research into physiotherapy for musculoskeletal conditions – NIHR Dissemination Centre (free PDF)

This new NIHR report brings together key research relevant to those delivering musculoskeletal physiotherapy services.

 


Study: The Right Diet Can Boost Potency of Cancer Drugs (in mice)

13 Jul, 2018 | 03:02h | UTC

The right diet can boost potency of cancer drugs – Nature News (free)

Original article: Suppression of insulin feedback enhances the efficacy of PI3K inhibitors – Nature (link to abstract – $ for full-text)

Related: Top oncologist to study effect of diet on cancer drugs – The Guardian (free)

“Diets appear to matter in mouse cancer Rx – can these preclinical findings be translated to humans?” (via @Aiims1742 see Tweet)

 


Review: Reading Mendelian Randomization Studies

13 Jul, 2018 | 03:00h | UTC

Research Methods & Reporting: Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians – The BMJ (free)

 


Randomized Trial: Alteplase vs Aspirin for Patients with Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits

13 Jul, 2018 | 02:58h | UTC

Effect of Alteplase vs Aspirin on Functional Outcome for Patients With Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits: The PRISMS Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Stopping the Alteplase Indication Creep – Emergency Medicine Literature of Note (free) AND Alteplase unlikely to reduce disability after mild stroke without disabling deficits – 2 Minute Medicine (free) AND Lytic No Better Than Aspirin for Mild Ischemic Stroke – MedPage Today (free registration required)

 


Systematic Review: Anticoagulation for Perioperative Thromboprophylaxis in People with Cancer

13 Jul, 2018 | 02:59h | UTC

Anticoagulation for perioperative thromboprophylaxis in people with cancer – Cochrane Library (free)

Summary: Blood thinners for the prevention of blood clots in people with cancer undergoing surgery – Cochrane Library (free)

 


Study: Impact of 2017 ACC/AHA Guidelines on Prevalence of Hypertension and Eligibility for Antihypertensive Treatment

13 Jul, 2018 | 02:56h | UTC

Impact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional study – The BMJ (free)

Commentary: Expert reaction to study looking at American blood pressure guidelines and how many people in the USA and China would be classed as having high blood pressure – Science Media Centre (free)

 


Australian Experiment Wipes Out Over 80% of Disease-Carrying Mosquitoes

13 Jul, 2018 | 02:53h | UTC

News Release: Trial wipes out more than 80 per cent of disease-spreading mozzie – Commonwealth Scientific and Industrial Research Organisation (CSIRO), Australian Government (free)

Commentary: Australian experiment wipes out over 80% of disease-carrying mosquitoes – CNN (free)

 


NICE Guideline: Management of Rheumatoid Arthritis in Adults

13 Jul, 2018 | 02:57h | UTC

Rheumatoid arthritis in adults: management – National Institute for Health and Care Excellence (free)

 


NICE Guideline: Brain Tumors (Primary) and Brain Metastases in Adults

13 Jul, 2018 | 02:57h | UTC

Brain tumours (primary) and brain metastases in adults – National Institute for Health and Care Excellence (free)

 


FDA Safety Alert: Warnings for Fluoroquinolones on Risks of Mental Health and Low Blood Sugar Adverse Reactions

13 Jul, 2018 | 02:50h | UTC

News Release: FDA updates warnings for fluoroquinolone antibiotics on risks of mental health and low blood sugar adverse reactions – U.S. Food and Drug Administration (free)

Commentaries: FDA Strengthens Warnings for Fluoroquinolone Antibiotics – MPR (free) AND FDA Announces Labeling Changes for Fluoroquinolones Due to Mental Health AEs, Blood Sugar Disturbances – MD Magazine (free)

 


Meta-Analysis: Efficacy of Short-Course Antibiotic Treatments for Community-Acquired Pneumonia

13 Jul, 2018 | 02:54h | UTC

Efficacy of short-course antibiotic treatments for community-acquired pneumonia in adults: A systematic review and meta-analysis – Antimicrobial Agents and Chemotherapy (link to abstract – $ for full-text)

Commentary: Is Short-Course Antibiotic Treatment for CAP Effective? – MPR (free)

 


Perspective: Fractional-Dose Yellow Fever Vaccination

13 Jul, 2018 | 02:52h | UTC

Fractional-Dose Yellow Fever Vaccination — Advancing the Evidence Base – New England Journal of Medicine (free)

Related Research: Immunogenicity of Fractional-Dose Vaccine during a Yellow Fever Outbreak — Preliminary Report – The New England Journal of Medicine (free)

 


Cohort Study: Effect of Cannabis Use in People with Chronic Non-Cancer Pain Prescribed Opioids

13 Jul, 2018 | 02:49h | UTC

Effect of cannabis use in people with chronic non-cancer pain prescribed opioids: findings from a 4-year prospective cohort study – The Lancet Public Health (free)

Commentaries: A painful lesson: are we repeating previous mistakes in pain management? – The Lancet Public Health (free) AND Use of illicit cannabis does not reduce chronic pain, according to new Australian study – RACGP (free)

Related: Efficacy and adverse effects of medical marijuana for chronic noncancer pain: Systematic review of randomized controlled trials – Canadian Family Physician (free) AND Benefits and Harms of Cannabis in Chronic Pain or Post-traumatic Stress Disorder: A Systematic Review – VA Evidence-based Synthesis Program (free) AND Cannabis products for adults with chronic neuropathic pain – Cochrane Library (free)

 


Study: 75% of African-Americans Have High Blood Pressure Before age 55

13 Jul, 2018 | 02:51h | UTC

Cumulative Incidence of Hypertension by 55 Years of Age in Blacks and Whites: The CARDIA Study – Journal of the American Heart Association (free)

Commentaries: Most black adults have high blood pressure before age 55 – AHA / ASA Newsroom (free) AND New CARDIA Data: 75% of African-Americans Have Hypertension by Age 55 – TCTMD (free)

 


Meta-Analysis: Marijuana Use, Respiratory Symptoms, and Pulmonary Function

13 Jul, 2018 | 02:49h | UTC

Marijuana Use, Respiratory Symptoms, and Pulmonary Function: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Smoking Marijuana May Be Tied to Cough, Sputum Production – HealthDay (free) AND Regular marijuana use is associated with development of respiratory issues – 2 Minute Medicine (free)

 


Meta-Analysis: Comparative Benefits and Harms of Basal Insulin Analogues for Type 2 Diabetes

13 Jul, 2018 | 02:46h | UTC

Comparative Benefits and Harms of Basal Insulin Analogues for Type 2 Diabetes: A Systematic Review and Network Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Newer, older insulin formulations may offer similar glucose-lowering effects – ACP Internist (free) AND HbA1c Reduction Similar in Old, New Basal Insulin Analogues – MedPage Today (free registration required)

 


USPSTF Statement: Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors

13 Jul, 2018 | 02:48h | UTC

Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorial: USPSTF Recommendations for Assessment of Cardiovascular Risk With Nontraditional Risk Factors: Finding the Right Tests for the Right Patients (free)

“The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of adding the ankle-brachial index (ABI), high-sensitivity C-reactive protein (hsCRP) level, or coronary artery calcium (CAC) score to traditional risk assessment for cardiovascular disease (CVD) in asymptomatic adults to prevent CVD events”.

 


Meta-Analysis: Multivitamins Do Not Reduce Cardiovascular Disease and Mortality

13 Jul, 2018 | 02:47h | UTC

Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis – Circulation: Cardiovascular Quality and Outcomes (free for a limited period)

Editorial: Multivitamins Do Not Reduce Cardiovascular Disease and Mortality and Should Not Be Taken for This Purpose: How Do We Know That? (free)

Commentaries: Study: Multivitamins Do Not Prevent Strokes, Heart Attacks or Cardiovascular Disease Deaths – University of Alabama at Birmingham, via NewsWise (free) AND Multivitamin-mineral supplements do not reduce heart disease, deaths – Reuters (free)

Related: Supplements Not Effective for CVD Prevention and Treatment (link to abstract and commentaries) AND Multivitamins are probably a waste of money (free commentaries)

 


Review: Optimal Pain Management for Patients with Cancer in the Modern Era

13 Jul, 2018 | 02:42h | UTC

Optimal pain management for patients with cancer in the modern era – CA: A Cancer Journal of Clinicians (free)

 


Study: Association of Early Introduction of Solids with Infant Sleep

13 Jul, 2018 | 02:45h | UTC

Association of Early Introduction of Solids With Infant Sleep: A Secondary Analysis of a Randomized Clinical Trial – JAMA Pediatrics (free)

Author Interview: Effects of Early Solid Food Introduction on Infant Sleep (free audio)

Commentaries: Babies fed solids earlier ‘sleep better’ – NHS Choices (free) AND Feeding your baby solids early may help them sleep, study suggests – The Guardian (free) AND Giving your baby solid food early won’t help them sleep better – The Conversation (free)

 


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