Daily Archives: May 23, 2018
Retrospective Cohort: Atrial Fibrillation Burden and Risk of Stroke in Adults with Paroxysmal Atrial Fibrillation
23 May, 2018 | 12:48h | UTCCommentaries: Atrial Fibrillation Burden and Stroke Risk – American College of Cardiology (free) AND Greater burden of atrial fibrillation linked to higher stroke risk – Kaiser Permanente, via EurekAlert (free)
Opinion: “Don’t Put That in My Heart Until You’re Sure It Really Works”
23 May, 2018 | 12:46h | UTCDon’t Put That in My Heart Until You’re Sure It Really Works – The New York Times (10 articles per month are free)
Commentary: Cardiologist wants more rigorous testing before devices, techniques are adopted – Cardiovascular Business (free)
See also: commentaries (PRO and Con) on the CABANA Trial
Review: Managing Depression in Patients with CAD
23 May, 2018 | 12:47h | UTCCommentaries: Depression in Patients With CAD – American College of Cardiology (free) AND Early Depression Diagnosis is Deadly Serious for Patients with Coronary Artery Disease – Florida State University, via NewsWise (free)
Disease Outbreak News: WHO Supports Ebola Vaccination of High Risk Populations in the DRC
23 May, 2018 | 12:44h | UTCCommentaries: Experimental Ebola Vaccinations, Considered ‘Paradigm Shift,’ Begin In Congo – NPR (free) AND Ebola vaccine drive launches in DRC as cases rise to 49 – CIDRAP (free) AND Congo begins giving experimental Ebola vaccine to medics – Reuters (free)
See also: Frequently asked questions on Ebola virus disease vaccine – World Health Organization (free)
“Health workers operating in affected areas in the Democratic Republic of the Congo are being vaccinated today and community outreach has started to prepare for the ring vaccination” (via @WHO see Tweet)
Review: Autism Spectrum Disorder
23 May, 2018 | 12:46h | UTCAutism spectrum disorder: advances in diagnosis and evaluation – The BMJ (free for a limited period)
Richard Lehman’s weekly journal review – 21 May 2018
23 May, 2018 | 12:45h | UTCRichard Lehman’s weekly journal review, 21 May 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Randomized Trial: Procalcitonin-Guided Therapy Did Not Reduce the Use of Antibiotics
23 May, 2018 | 12:43h | UTCCommentaries: Procalcitonin-Guided Care Doesn’t Reduce Antibiotics for Lower Respiratory Tract Infection – NEJM Journal Watch (free) AND Infection blood test of limited value in reducing antibiotic use – MedicalXpress (free)
Guideline: Clinical use of Resuscitative Endovascular Balloon Occlusion of the Aorta
23 May, 2018 | 12:44h | UTCCommentary: EMCrit Guest Post – The good, the bad, and the ugly of the Joint Statement on REBOA by Zaffer Qasim (free)
Source: Critical Care Reviews Newsletter
Randomized Controlled Trial: Dupilumab in Glucocorticoid-Dependent Severe Asthma
23 May, 2018 | 12:39h | UTCRelated Article: Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma – New England Journal of Medicine (free)
Editorial: New Biologics for Asthma (free)
Commentary: Dupilumab Improves Severe Asthma – NEJM Physician’s First Watch (free)
Comparative Effectiveness Trial: Chiropractic Care Improves Disability in Low Back Pain
23 May, 2018 | 12:38h | UTCCommentaries: Innovating to Improve Care for Low Back Pain in the Military: Chiropractic Care Passes Muster – JAMA Network Open (free) AND Chiropractic Care Improves Usual Management for Low Back Pain – Medscape (free registration required) AND Adding chiropractic to back pain care may reduce disability – Reuters (free)
Cohort Study: Grip Strength and All-Cause Mortality
23 May, 2018 | 12:37h | UTCCommentary: Strong grip may predict longer life at all ages – Reuters (free)
New BMJ Series: Universal Health Coverage
23 May, 2018 | 12:35h | UTC“The BMJ in partnership with The Harvard Global Health Institute are launching a collection of articles that will explore how to achieve effective Universal Health Coverage (UHC)”
– Home
– Analysis: Rethinking assumptions about delivery of healthcare: implications for universal health coverage (free)
– Opinion: Non-communicable diseases must be part of Universal Health Coverage (free)
– Opinion: Ensuring effective investments in Universal Health Coverage at the national level
– Opinion: Paying and investing in community health workers accelerates universal health coverage
Perspective: How PrEP to Prevent HIV May be Fueling a Rise in Other STDs
23 May, 2018 | 12:36h | UTCHow PrEP, the pill to prevent HIV, may be fueling a rise in other STDs – Vox (free)
Original Meta-Analysis: Effects of Pre-exposure Prophylaxis for the Prevention of Human Immunodeficiency Virus Infection on Sexual Risk Behavior in Men Who Have Sex With Men: A Systematic Review and Meta-analysis – Clinical Infectious Diseases (link to abstract – $ for full-text)
See also: Guidelines on HIV Pre-exposure Prophylaxis (all free)
Cohort Study: Egg Consumption and Cardiovascular Disease
23 May, 2018 | 12:32h | UTCCommentaries: BMJ’s scrambled message on eggs and heart disease: a recipe for rotten news coverage – Health News Review (free) AND Expert reaction to eggs and CVD – Science Media Centre (free) AND No, Eating Eggs Will NOT Protect You From Cardiovascular Death – The Methods Man (free)
Pro/Con Debate: CTA as the Initial Test in Stable Angina
23 May, 2018 | 12:33h | UTCPro: Coronary CTA Should Be the Initial Test in Most Patients with Stable Chest Pain (free)
Con: Coronary CTA Should Be the Initial Test in Most Patients with Stable Chest Pain (free)
Meta-Analysis: Corticosteroids for Patients with Septic Shock
23 May, 2018 | 12:28h | UTCLow-dose corticosteroids for adult patients with septic shock: a systematic review with meta-analysis and trial sequential analysis – Critical Care Medicine (free for a limited period)
Source: Critical Care Reviews Newsletter
“In adults with septic shock treated with low dose corticosteroids, short- and longer-term mortality are unaffected, adverse events increase, but duration of shock, mechanical ventilation and ICU stay are reduced”.
Guideline: Use of Atraumatic Needles in All Patients Undergoing Lumbar Puncture
23 May, 2018 | 12:32h | UTCRapid Recommendations: Atraumatic (pencil-point) versus conventional needles for lumbar puncture: a clinical practice guideline – The BMJ (free)
“We issue a strong recommendation for use of atraumatic needles in all patients (adults and children) undergoing lumbar puncture because they decrease complications and are no less likely to work than conventional needles”
Studies: More vs Less Frequent Follow-up Testing and Colorectal Cancer Outcomes
23 May, 2018 | 12:31h | UTCEffect of More vs Less Frequent Follow-up Testing on Overall and Colorectal Cancer–Specific Mortality in Patients With Stage II or III Colorectal Cancer: The COLOFOL Randomized Clinical Trial – JAMA (free for a limited period)
Related Study: Association Between Intensity of Posttreatment Surveillance Testing and Detection of Recurrence in Patients With Colorectal Cancer (free for a limited period)
Commentaries: Surveillance intensity not associated with earlier detection of recurrence or improved survival in colorectal cancer – MedicalXpress (free) AND CRC: No Increase in Survival with Stepped-Up Surveillance – MedPage Today (free registration required) AND CRC recurrence surveillance studies: No benefit to high-intensity strategy – Oncology Practice (free)
Meta-Analysis: Aldosterone Antagonists for ST-Segment Elevation Myocardial Infarction Without Heart Failure
23 May, 2018 | 12:28h | UTCAldosterone Antagonist Therapy and Mortality in Patients With ST-Segment Elevation Myocardial Infarction Without Heart Failure: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Mineralocorticoid Receptor Antagonists in ST-Segment Elevation Myocardial Infarction – JAMA Internal Medicine (free for a limited period)
Aldosterone antagonists are beneficial for patients with STEMI and reduced ejection fraction. This meta-analysis suggests that patients with STEMI and LVEF greater than 40% or without heart failure also have improved outcomes with aldosterone antagonists.
Research: Clinical Features of Guillain-Barré Syndrome With vs Without Zika Virus Infection
23 May, 2018 | 12:23h | UTCClinical Features of Guillain-Barré Syndrome With vs Without Zika Virus Infection, Puerto Rico, 2016 – JAMA Neurology (link to abstract – $ for full-text)
Commentary: Study: GBS symptoms more severe when caused by Zika – CIDRAP (free)
Randomized Trial: Five-Year Outcomes with PCI Guided by FFR
23 May, 2018 | 12:27h | UTCFive-Year Outcomes with PCI Guided by Fractional Flow Reserve – New England Journal of Medicine (free)
Commentary: FFR in PCI for Stable CAD: Lasting Benefit Shown by FAME 2, SCAAR Data – TCTMD (free)
Perspective: Ten Dubious Beliefs in Neurocritical Care
23 May, 2018 | 12:26h | UTCTen dubious beliefs in neurocritical care – PulmCrit (free)
Cohort Study: Using Alternatives to the Car and Mortality Risk
23 May, 2018 | 12:19h | UTCUsing alternatives to the car and risk of all-cause, cardiovascular and cancer mortality – Heart (free)
Commentaries: Avoiding the car for travel could significantly lower risk of illness and death – BMJ, via EurekAlert (free) AND Ditching the car may reduce your risk of dying from heart disease and stroke by almost a third – The Conversation (free)
Research: Physiology-Stratified Analysis of ORBITA
23 May, 2018 | 12:22h | UTCCommentaries: New ORBITA Findings May Offer Modest Symptomatic Pain Relief To Interventional Cardiologists – Cardiobrief (free) AND New ORBITA Insights: Invasive Physiology Tests Track Closely With Ischemia, but Not Symptom Improvement – TCTMD (free)
See more on the repercussions of the ORBITA Trial: Percutaneous coronary intervention in stable angina (ORBITA) (link to abstract and commentaries) AND Placebo Effect of the Heart (free commentaries) AND Sham Surgeries: A Tale of Medical Reversals & the Role of the Media (free commentaries)
Randomized Trial: Cannabidiol Reduces Seizures in Patients with Lennox–Gastaut Syndrome
23 May, 2018 | 12:22h | UTCEffect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Cannabidiol significantly reduces seizures in patients with severe form of epilepsy – NYU School of Medicine (free) AND Cannabis Drug Reduces Drop Seizures in Severe Epilepsy – Medscape (free registration required) AND Cannabidiol Significantly Reduces Seizures in Patients with Lennox-Gastaut Syndrome – MD Magazine (free)