Daily Archives: March 8, 2018
ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes
8 Mar, 2018 | 22:32h | UTCCommentary: Major Medical Associations Feud Over Diabetes Guidelines – NPR (free)
“Clinicians should aim to achieve an HbA1c level between 7% and 8% in most patients with type 2 diabetes”
Guideline: Treatment of infections caused by multidrug-resistant Gram-negative bacteria
8 Mar, 2018 | 22:33h | UTCTreatment of infections caused by multidrug-resistant Gram-negative bacteria: report of the British Society for Antimicrobial Chemotherapy/Healthcare Infection Society/British Infection Association Joint Working Party – Journal of Antimicrobial Chemotherapy (free) (via @ABsteward)
Novel subgroups of adult-onset diabetes and their association with outcomes
8 Mar, 2018 | 22:29h | UTCNovel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: 5 Classifications of Diabetes Proposed – Physician’s First Watch (free) AND Should diabetes be divided into 5 categories to improve treatment? – Cardiovascular Business (free) AND Diabetes Consists of Five Types, Not Two, Say Researchers – Medscape (free registration required)
New Guide to Infection Control in The Hospital
8 Mar, 2018 | 22:31h | UTCNew Guide to Infection Control in The Hospital – International Society for Infectious Diseases (free)
A free, online resource on the principles and interventions needed to reduce healthcare associated infections, with suggested control measures across different resource levels.
Meta-Analysis: Drug treatment effects on outcomes in heart failure with preserved ejection fraction
8 Mar, 2018 | 22:30h | UTCEditorial: Pharmacological strategies in heart failure with preserved ejection fraction: time for an individualised treatment strategy? (free)
Commentary: Heartbeat: Is there any effective therapy for heart failure with preserved ejection fraction? (free)
In this meta-analysis of RCT testing treatments for patients with heart failure with preserved ejection fraction, only beta-blockers demonstrated reductions in all-cause and cardiovascular mortality.
Clinical Practice Guideline: Hoarseness
8 Mar, 2018 | 22:28h | UTCSee also: Executive Summary
2018 AHA/ASA Ischemic Stroke Updates
8 Mar, 2018 | 22:26h | UTCSummary for ED-relevant care: 2018 AHA/ASA Ischemic Stroke Updates – emDocs (free)
Original guideline: 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association (free PDF)
The Challenge of Doctor-Patient Relations in the Internet Age
8 Mar, 2018 | 22:27h | UTCThe Challenge of Doctor-Patient Relations in the Internet Age – The New York Times (10 articles per month are free)
Related: E-patients hold key to the future of healthcare – The BMJ Opinion (free)
One-Month Tuberculosis Prophylaxis as Effective as Nine-Month Regimen for People Living with HIV
8 Mar, 2018 | 22:24h | UTCOne-Month Tuberculosis Prophylaxis as Effective as Nine-Month Regimen for People Living with HIV – National Institute of Allergy and Infectious Diseases (free) (via @iasociety see Tweet)
Related: New ways to fight HIV and tuberculosis emerge at AIDS conference – Science (free)
The Tobacco Atlas, Sixth Edition
8 Mar, 2018 | 22:21h | UTCThe Tobacco Atlas, Sixth Edition (free PDF)
News Release: Big tobacco is targeting the world’s most vulnerable to increase profits – American Cancer Society (free)
See companion website: TobaccoAtlas.org
Related: Explore the GBD tool to compare tobacco risks globally – IHME (free interactive tool)
Research: Fluoroquinolone use and risk of aortic aneurysm and dissection
8 Mar, 2018 | 22:17h | UTCFluoroquinolone use and risk of aortic aneurysm and dissection: nationwide cohort study – The BMJ (free)
Related: Aortic Dissection and Aortic Aneurysms Associated with Fluoroquinolones: A Systematic Review and Meta-Analysis – American Journal of Medicine (free) AND Fluoroquinolones and collagen associated severe adverse events: a longitudinal cohort study – BMJ Open (free) AND Risk of Aortic Dissection and Aortic Aneurysm in Patients Taking Oral Fluoroquinolone – JAMA Internal Medicine (free)
Proton pump inhibition therapy and risk of oesophageal cancer
8 Mar, 2018 | 22:14h | UTCMaintenance proton pump inhibition therapy and risk of oesophageal cancer – Cancer Epidemiology (link to abstract – $ for full-text)
Commentary: Long-term PPI Use and Increased Esophageal CA Risk – Medscape (free registration required)
Related studies suggesting a link with gastric cancer: Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study – Gut (link to abstract – $ for full-text) AND Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden – BMJ Open (free)
This observational study suggests a possible link.
ESC position paper on spontaneous coronary artery dissection
8 Mar, 2018 | 22:19h | UTCCommentary with key points to remember: European Position Paper on Spontaneous Coronary Artery Dissection – American College of Cardiology, Latest in Cardiology (free)
Related position statement: Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association – Circulation (free)
Self-Management of an Inferior ST-Segment Elevation Myocardial Infarction
8 Mar, 2018 | 22:15h | UTCCase report: Self-Management of an Inferior ST-Segment Elevation Myocardial Infarction – New England Journal of Medicine (free)
Graduate students need more mental health support
8 Mar, 2018 | 22:16h | UTCGraduate students need more mental health support, new study highlights – Science (free) AND Mental Health Crisis for Grad Students – Inside Higher Ed (free) AND Depression, anxiety high in graduate students, survey shows – University of Texas Health Science Center, via ScienceDaily (free)
Research: Metformin use in PCOS pregnancies increases the risk of offspring overweight at 4 years of age
8 Mar, 2018 | 22:13h | UTCMetformin use in PCOS pregnancies increases the risk of offspring overweight at 4 years of age; follow-up of two RCTs – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)
Commentaries: Diabetes drug use during pregnancy linked to child’s weight – The Endocrine Society, via ScienceDaily (free) AND Diabetes drug use during pregnancy affects child’s weight – OnMedica (free) AND Metformin in Pregnancy May Increase Childhood Obesity Risk – Medscape (free registration required)
The Australian Rheumatology Association’s ‘top five’ list of investigations and interventions doctors and patients should question
8 Mar, 2018 | 22:12h | UTCEVOLVE: The Australian Rheumatology Association’s ‘top five’ list of investigations and interventions doctors and patients should question – Internal Medicine Journal (free) (via @RSiemieniuk)
See other lists of low-value practices in Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Another interesting list of commonly used low-value practices that should be questioned.
Research: Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality
8 Mar, 2018 | 22:07h | UTCEffect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: One-off PSA screening for prostate cancer does not save lives – eCancer News (free)
“Largest ever prostate cancer trial – CAP – published in the JAMA. No effect from low intensity PSA screening on prostate cancer mortality at 10 years”. (via @KariTikkinen see Tweet)
Meta-Analysis: Diet during pregnancy and infancy and risk of allergic or autoimmune disease
8 Mar, 2018 | 22:10h | UTCCommentary: Probiotics and fish oil in pregnancy may reduce allergies in children – NHS Choices (free) AND Diet During Pregnancy May Cut Offspring Allergy Risk – MedPage Today (free registration required) AND Probiotics and Fish Oil During Pregnancy May Curb Allergies in Kids – The New York Times (10 articles per month are free)
Inflammatory Bowel Disease Increases Likelihood of a Heart Attack
8 Mar, 2018 | 22:11h | UTCInflammatory Bowel Disease Increases Likelihood of a Heart Attack – American College of Cardiology (free) AND Inflammatory bowel disease may raise heart attack risk – Medical News Today (free) AND Those with IBD twice as likely to have heart attack – Cardiovascular Business (free)
Systematic review: Effectiveness of brief alcohol interventions in primary care populations
8 Mar, 2018 | 22:09h | UTCEffectiveness of brief alcohol interventions in primary care populations – Cochrane Library (free)
In general practice or emergency care settings, brief alcohol interventions can reduce alcohol consumption and related harm.
Guideline on choice of inotropic agent for patients with acute circulatory failure
8 Mar, 2018 | 22:08h | UTCSource: Critical Care Reviews Newsletter
Research: Effect of β‐Blockers Beyond 3 Years After Acute Myocardial Infarction
8 Mar, 2018 | 22:03h | UTCEffect of β‐Blockers Beyond 3 Years After Acute Myocardial Infarction – Journal of the American Heart Association (free for a limited period)
Related article: B-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction – Journal of The American College of Cardiology (free)
Randomized controled trial: Opioid vs Nonopioid Medications in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain
8 Mar, 2018 | 22:06h | UTCEffect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Opioids Don’t Beat Other Medications For Chronic Pain – NPR (free) AND More Data Opioids No Better for Chronic Back, Arthritis Pain – Medscape (free registration required) AND Opioids no better than NSAIDs for chronic back or arthritis pain – Reuters (free)
Related: Opioid Wisely – Choosing Wisely Canada (free) AND Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)
Cancer screening recommendations: an international comparison of high income countries
8 Mar, 2018 | 22:02h | UTCCancer screening recommendations: an international comparison of high income countries – Public Health Reviews (free) (via @hildabast see Tweet)