Daily Archives: February 5, 2018 | LinksMedicus Free Medical News & Perspectives

Research: Catheter Ablation for Atrial Fibrillation with Heart Failure

5 Feb, 2018 | 16:51h | UTC

Catheter Ablation for Atrial Fibrillation with Heart Failure – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Catheter ablation better than pharmacological atrial fibrillation therapies – University of Utah Health, via EurekAlert (free)

“In patients w/heart failure & atrial fibrillation, catheter ablation lowers rate of death and hospitalization for worsening HF vs. medical therapy”. (via @NEJM see Tweet)

Early use of tranexamic acid reduces bleeding more effectively

5 Feb, 2018 | 16:51h | UTC

Early use of tranexamic acid reduces bleeding more effectively – NIHR Signal (free)

Original article: Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients – The Lancet (free) AND Invited Commentary: Tranexamic acid: is it about time? (free)

“It is now clearer that every 15-minute delay after the first hour can reduce survival by about 10%”.

Guideline: Gastrointestinal Complications in Adult Cancer Patients

5 Feb, 2018 | 16:53h | UTC

Guideline: Diagnosis and management of gastrointestinal complications in adult cancer patients – German Society of Hematology and Medical Oncology (free)

Research: High performance plasma amyloid-β biomarkers for Alzheimer’s disease

5 Feb, 2018 | 16:48h | UTC

High performance plasma amyloid-β biomarkers for Alzheimer’s disease – Nature (link to abstract – $ for full-text)

Commentaries: Expert reaction to biomarkers for amyloid-beta in Alzheimer’s disease – Science Media Centre (free) AND A Big Step toward a Blood Test for Alzheimer’s – Scientific American (free) AND Simple blood test spots dementia protein – Nature News (free) AND Alzheimer’s hope as scientists unveil blood test for early signs – The Guardian (free)

AHA Scientific Statement: Cardiovascular Disease and Breast Cancer

5 Feb, 2018 | 16:49h | UTC

Cardiovascular Disease and Breast Cancer: Where These Entities Intersect: A Scientific Statement From the American Heart Association – Circulation (free PDF)

Commentaries: Breast cancer treatments may increase the risk of heart disease – AHA / ASA Newsroom (free) AND Heart group warns of cardiovascular risks after treatment for breast cancer – STAT (free)

Research: Effects of Preschool in Educational Attainment at 35 Years of Age

5 Feb, 2018 | 16:45h | UTC

A Multicomponent, Preschool to Third Grade Preventive Intervention and Educational Attainment at 35 Years of Age – JAMA Pediatrics (free)

Commentaries: Longer Early Childhood Intervention Linked To Greater Post-Secondary Attainment – MedicalResearch.com (free) AND Does Preschool Make a Long-Term Difference? – MedPage Today (free) AND Graduates of early childhood program show greater educational gains as adults – EurekAlert (free)

Intravenous antibiotics, administered over 3 hours, are linked to lower death rates in sepsis

5 Feb, 2018 | 16:50h | UTC

Intravenous antibiotics, administered over 3 hours, are linked to lower death rates in sepsis – NIHR Signal (free)

Original article: Prolonged versus short-term intravenous infusion of antipseudomonal β-lactams for patients with sepsis: a systematic review and meta-analysis of randomised trials – The Lancet Infectious Diseases (link to abstract – $ for full-text)

Research: Migraine Associated with Increased Risk of Cardiovascular Diseases

5 Feb, 2018 | 16:47h | UTC

Migraine and risk of cardiovascular diseases: Danish population based matched cohort study – The BMJ (free)

Editorial: Migraine and risk of cardiovascular disease (free)

Commentaries: Migraine Associated With Broad Range of CVD Diagnoses in Nationwide Study – TCTMD (free) AND Migraine Linked To Increased Risk of Stroke, AFib, PE and Cardiovascular Disease – MedicalResearch.com (free)

A Revolution in Health Care is Coming

5 Feb, 2018 | 16:27h | UTC

A revolution in health care is coming – The Economist (a few articles per month are free) (via @equitylist)

“Welcome to Doctor You”

Research: Prevalence of Pulmonary Embolism in Patients With Syncope

5 Feb, 2018 | 16:46h | UTC

Prevalence of Pulmonary Embolism in Patients With Syncope – JAMA Internal Medicine (free for a period)

Author Interview: Prevalence of Pulmonary Embolism in Patients With Syncope (free)

Commentaries: Prevalence of PE Low for Patients Presenting to ER With Syncope – Physician’s Weekly (free) AND Study Finds Pulmonary Embolus Rarely the Cause of Syncope – MedicalResearch.com (free)

Proton Pump Inhibitors: Review of Emerging Concerns

5 Feb, 2018 | 16:23h | UTC

Proton Pump Inhibitors: Review of Emerging Concerns – Mayo Clinic Proceedings (free)

New Document for Patients: Advanced Health Directive for Dementia

5 Feb, 2018 | 16:26h | UTC

One Day Your Mind May Fade. At Least You’ll Have a Plan – The New York Times (10 articles per month are free)

Free download: Health Directive for Dementia (free PDF) from Advanced Directive for Dementia

Source: New document allows advance planning for dementia – Univadis (free registration required)

“A Simple Way to Document the Medical Care You Would Want If You Had Dementia”

Research: D-dimer Predicts Long-Term Cause-Specific Mortality, Cardiovascular Events and Cancer

5 Feb, 2018 | 16:22h | UTC

D-dimer Predicts Long-Term Cause-Specific Mortality, Cardiovascular Events and Cancer in Stable Coronary Heart Disease Patients: The LIPID Study – Circulation (link to abstract – $ for full-text)

Commentary: D-dimer Predicts Long-Term Mortality, Vascular Events, Cancer – American College of Cardiology, Latest in Cardiology (free) AND D-Dimer Predicts CV, Cancer Mortality Over 16 Years in Patients With Stable CHD – Medscape (free registration required)

BSH Guideline: Thrombotic and Haemostatic Issues in Paediatric Malignancy

5 Feb, 2018 | 16:21h | UTC

BSH Guideline: management of thrombotic and haemostatic issues in paediatric malignancy – British Journal of Haematology (free)

Pediatrics Journal Supplement – Congenital Zika Syndrome

5 Feb, 2018 | 16:25h | UTC

Pediatrics Journal Supplement – Congenital Zika Syndrome (via @greg_folkers)

– Zika and Public Health: Understanding the Epidemiology and Information Environment (free)

– Public Health Approach to Addressing the Needs of Children Affected by Congenital Zika Syndrome (free)

– Development of Infants With Congenital Zika Syndrome: What Do We Know and What Can We Expect? (free)

– Ophthalmologic Manifestations Associated With Zika Virus Infection (free)

– Motor Abnormalities and Epilepsy in Infants and Children With Evidence of Congenital Zika Virus Infection (free)

– The Likely Impact of Congenital Zika Syndrome on Families: Considerations for Family Supports and Services (free)

Meta-analysis: Omega-3 Fatty Acid Supplements Don’t Reduce Cardiovascular Risk

5 Feb, 2018 | 16:18h | UTC

Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks: Meta-analysis of 10 Trials Involving 77 917 Individuals – JAMA Cardiology (free)

Commentary: Omega-3 Supplements Don’t Protect Against Heart Disease – The New York Times (10 articles per month are free)

Omega-3 fatty acids did not prevent fatal or nonfatal coronary heart disease or any major vascular events.

Research: Traumatic Brain Injury and the Risk of Dementia Diagnosis

5 Feb, 2018 | 16:16h | UTC

Traumatic brain injury and the risk of dementia diagnosis: A nationwide cohort study – PLOS One (free)

Commentaries: TBI is associated with increased dementia risk for decades after injury – PLOS, via ScienceDaily (free) AND More evidence traumatic brain injuries raise later dementia risk – Reuters (free)

“Using longitudinal, case-control, and sibling-matched analyses of nationwide data from Sweden, Peter Nordström & Anna Nordström describe the association between TBI and dementia, its time course, and the influence of familial factors”. (via @PLOSMedicine see Tweet)