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Daily Archives: January 26, 2018

To Care Is Human — Collectively Confronting the Clinician-Burnout Crisis

26 Jan, 2018 | 01:42h | UTC

Perspectives: To Care Is Human — Collectively Confronting the Clinician-Burnout Crisis – New England Journal of Medicine (free) AND Beyond Burnout — Redesigning Care to Restore Meaning and Sanity for Physicians (free)

Related: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free) AND Counting the costs: U.S. hospitals feeling the pain of physician burnout – Reuters (free)

 


2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke

26 Jan, 2018 | 01:44h | UTC

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association (free PDF)

Commentaries: More stroke patients eligible for crucial treatments under new guidelines – American Heart Association News (free) AND More stroke patients may receive crucial treatments under new guideline – AHA/ASA Newsroom (free)

“A new guideline for treating acute ischemic stroke recommends an increased treatment window for mechanical clot removal from six hours to up to 24 hours in certain patients with clots in large vessels”. (from AHA/ASA Newsroom)

 


Research: Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus

26 Jan, 2018 | 01:39h | UTC

Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus – JAMA Neurology (free for a period)

Editorial: Time May Be of the Essence in the Treatment of Pediatric Patients With Refractory Convulsive Status Epilepticus (free)

Commentary: Delays Raise Death Risk in Kids with Status Epilepticus – MedPage Today (free registration required)

“These findings may change the perception of acute seizure and status epilepticus treatment, tentatively converting it into an extremely time-sensitive emergency that is similar to stroke or other cardiovascular events”.

 


Research: Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

26 Jan, 2018 | 01:43h | UTC

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging – New England Journal of Medicine (free)

Commentaries: Brain-scan guided emergency stroke treatment can save more lives – NIH News Releases (free) AND Study confirms late clot extraction can save brain cells of stroke victims – Reuters (free) AND New Findings Could Save Lives of More Stroke Patients – The New York Times (10 articles per month are free)

Related article: Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct – New England Journal of Medicine (link to abstract – $ for full-text)

 


Guideline: Deprescribing Antipsychotics for Behavioural and Psychological Symptoms of Dementia and Insomnia

26 Jan, 2018 | 01:37h | UTC

Deprescribing antipsychotics for behavioural and psychological symptoms of dementia and insomnia: Evidence-based clinical practice guideline – Canadian Family Physician (free)

Related: Canadian Deprescribing Network (CaDeN) (free) AND CaDeN Deprescribing Guidelines and Algorithms (free) AND Deprescribing guidelines for the elderly – Ontario Pharmacy Evidence Network (free) AND Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND 11 Drugs You Should Seriously Consider Deprescribing – Medscape Slideshow (free registration required) AND Current and future perspectives on the management of polypharmacy – BMC Family Practice (free)

 


Guideline: Oesophago-Gastric Cancer

26 Jan, 2018 | 01:32h | UTC

Guideline: Oesophago-gastric cancer: assessment and management in adults – National Institute for Health and Care Excellence (NICE) (free)

 


Guideline: Age-related macular degeneration

26 Jan, 2018 | 01:31h | UTC

Age-related macular degeneration – National Institute for Health and Care Excellence (NICE) (free)

 


Guideline on the Pharmacological Treatment of People with Multiple Sclerosis

26 Jan, 2018 | 01:33h | UTC

ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis – European Journal of Neurology (free)

 


Research: Trends in Survival After In-Hospital Cardiac Arrest During Nights and Weekends

26 Jan, 2018 | 01:26h | UTC

Trends in Survival After In-Hospital Cardiac Arrest During Nights and Weekends – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Survival From In-Hospital Cardiac Arrest Improves But Still Worse on Nights and Weekends – MedicalResearch.com (free)

AND Hospital patients less likely to survive ‘off-hours’ cardiac arrest – Reuters (free) AND You are still more likely to die in a hospital on the weekend – CNN (free)

See also a recent meta-analysis showing the “weekend effect” in surgical patients

 


Research: Left Atrial Appendage Occlusion and Readmission for Thromboembolism Among Patients With Atrial Fibrillation Undergoing Concomitant Cardiac Surgery

26 Jan, 2018 | 01:29h | UTC

Association Between Left Atrial Appendage Occlusion and Readmission for Thromboembolism Among Patients With Atrial Fibrillation Undergoing Concomitant Cardiac Surgery – JAMA (free)

Commentaries: Largest Study to Date Supports Surgical LAA Closure in A-fib Patients – TCTMD (free) AND Thromboembolism Less Likely With LAA Closure Added to Cardiac Surgery – MedPage Today (free registration required)

Randomized trials are needed to confirm these interesting findings. 

 


Guideline: Advocacy for Improving Nutrition in the First 1000 Days To Support Childhood Development and Adult Health

26 Jan, 2018 | 01:20h | UTC

Advocacy for Improving Nutrition in the First 1000 Days To Support Childhood Development and Adult Health – Pediatrics (free)

Commentary: AAP Issues Recommendations for Improving Early-Childhood Nutrition – Physician’s First Watch (free) AND These Are the Best Foods for a Baby’s Brain – TIME (free)

 


Report: Public Health Consequences of E-Cigarettes

26 Jan, 2018 | 01:24h | UTC

Report: Public Health Consequences of E-Cigarettes – National Academies of Sciences, Engineering, and Medicine (free PDF)

Press release: New Report One of the Most Comprehensive Studies on Health Effects of E-Cigarettes; Finds That Using E-Cigarettes May Lead Youth to Start Smoking, Adults to Stop Smoking (free)

Commentaries: E-Cigarettes Likely Encourage Kids To Try Tobacco But May Help Adults Quit – NPR (free) AND 4 big takeaways from the most comprehensive report on e-cigarettes yet – VOX (free) AND Vaping Can Be Addictive and May Lure Teenagers to Smoking, Science Panel Concludes – The New York Times (10 articles per month are free)

 


Research: Antithyroid Drugs and Congenital Malformations

26 Jan, 2018 | 01:23h | UTC

Antithyroid Drugs and Congenital Malformations: A Nationwide Korean Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: First trimester exposure to antithyroid drugs associated with increased risk of birth defects – 2 Minute Medicine (free) AND Use of Antithyroid Drugs Early in Pregnancy Tied to Birth Defect Risk – Physician’s First Watch (free) AND First trimester exposure to antithyroid drugs linked with birth defects – OnMedica (free)

 


Fri, January 26 – 10 Stories of The Day!

26 Jan, 2018 | 00:45h | UTC

 

1 – Acute Myocardial Infarction after Laboratory-Confirmed Influenza Infection – New England Journal of Medicine (link to abstract – $ for full-text)

Quick Take Video Summary: Myocardial Infarction after Influenza Infection (free)

Commentaries: Flu infection raises risk of heart attack in week after diagnosis – STAT (free) AND Flu Virus Can Trigger A Heart Attack – NPR (free) AND Flu increases the risk of heart attack – Reuters (free)

The researchers identified a six-fold increased risk of heart attack in the 7 days after a flu diagnosis.

 

2 – Low cigarette consumption and risk of coronary heart disease and stroke: meta-analysis of 141 cohort studies in 55 study reports – The BMJ (free)

Editorial: Just one cigarette a day seriously elevates cardiovascular risk (free)

Commentaries: CHD and stroke risk seriously elevated with just one daily cigarette – OnMedica (free) AND Smoking Even One Cigarette a Day Raises Cardiovascular Risk – Medscape (free registration required) AND Smoking Just One Cigarette a Day Carries Substantial Risks – Physician’s First Watch (free)

 

3 – Guideline: Duration of Contact Precautions for Acute-Care Settings – Society for Healthcare Epidemiology of America (SHEA) (free)

Summary and commentary: New guidelines issued on contact precautions for C. diff, resistant infections – ACP Hospitalist (free)

 

4 – Guideline: International technical guidance on sexuality education: An evidence-informed approach – UNESCO (free PDF)

News release: UN urges Comprehensive Approach to Sexuality Education – UNESCO (free)

Commentary: UN issues more progressive guidelines on sex education – Devex (free)

 

5 – Association of Resting Heart Rate and Temporal Changes in Heart Rate With Outcomes in Participants of the Atherosclerosis Risk in Communities Study – JAMA Cardiology (free)

Commentaries: Heart Rate Changes Over Time Hint at Higher Cardiovascular Risk – TCTMD (free) AND Increasing Heart Rate Over Time May Predict CV Events – MedPage Today (free registration required)

 

6 – Existing and potential infection risk zones of yellow fever worldwide: a modelling analysis – The Lancet Global Health (free)

 

7 – Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: Systematic review and meta-analysis – PLOS Medicine (free)

Commentaries: Caesarean section versus natural birth – an obstetrician examines a new review  – The Conversation (free) AND Expert reaction to review paper looking at long-term risks and benefits of caesarean sections – Science Media Centre (free) AND C-sections linked to long-term risks and benefits – PLOS, via EurekAlert (free) AND Long-term risks and benefits of C-section revealed – Medical News Today (free)

As a scientist, I can appreciate the effort made in conducting a systematic review on the topic, but as an obstetrician I worry that the results can be over-interpreted by patients – not to mention obstetricians and midwives – and caesarean section “marketed” as a safe way to avoid pelvic floor problems”. (from The Conversation)

 

8 – Preoperative physiotherapy for the prevention of respiratory complications after upper abdominal surgery: pragmatic, double blinded, multicentre randomised controlled trial – The BMJ (free)

Commentaries: Pre-surgery breathing physio halves risk of complications – OnMedica (free) AND Respiratory Training Before Surgery Significantly Reduces Risk of Postoperative Lung Complications – Medindia (free) AND Breath Training Before Surgery Halves Postoperative Pneumonia Risk – Medscape (free registration required)

 

9 – Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer – Cell (free)

Commentaries: These monkey twins are the first primate clones made by the method that developed Dolly – Science (free) AND First monkeys cloned with technique that made Dolly the sheep – Nature (free) AND How afraid of human cloning should we be? – The Guardian (free)

 

10 – Projections of multi-morbidity in the older population in England to 2035: estimates from the Population Ageing and Care Simulation (PACSim) model – Age and Ageing (free)

Commentaries: Number of older people with four or more diseases will double by 2035 – OnMedica (free) AND Number of older people with four or more diseases will double by 2035 – Newcastle University (free) AND We’ll live longer but suffer more ill-health by 2035, says study – The Guardian (free)

See related articles and commentaries on Designing Health Care Systems for Patients with Complex Needs (free)

 


Research: Association of Exposure to Communities With Higher Ratios of Obesity with Increased Body Mass Index and Risk of Overweight and Obesity

26 Jan, 2018 | 00:42h | UTC

Association of Exposure to Communities With Higher Ratios of Obesity with Increased Body Mass Index and Risk of Overweight and Obesity Among Parents and Children – JAMA Pediatrics (link to abstract – $ for full-text)

Commentaries: Your Neighbors, Your Waistline – New York Times (10 articles per month are free) AND Is ‘Social Contagion’ at Play When It Comes to Obesity Risk? – MedPage Today (free registration required) AND Location of military assignment tied to obesity risk for families – Cardiovascular Business (free)

 


Opinion: Robust Research Needs Many Lines of Evidence

26 Jan, 2018 | 01:18h | UTC

Robust research needs many lines of evidence – Nature (free)

 


Research: Number of Older People With Four or More Diseases will Double by 2035

26 Jan, 2018 | 00:40h | UTC

Projections of multi-morbidity in the older population in England to 2035: estimates from the Population Ageing and Care Simulation (PACSim) model – Age and Ageing (free)

Commentaries: Number of older people with four or more diseases will double by 2035 – OnMedica (free) AND Number of older people with four or more diseases will double by 2035 – Newcastle University (free) AND We’ll live longer but suffer more ill-health by 2035, says study – The Guardian (free)

See related articles and commentaries on Designing Health Care Systems for Patients with Complex Needs (free)

 


Starting Antiretroviral Therapy Immediately after HIV Diagnosis Reduces Transmission of the Virus

26 Jan, 2018 | 01:15h | UTC

Starting antiretroviral therapy immediately after HIV diagnosis reduces transmission of the virus – NIHR Signal (free)

Original article: Implications for a policy of initiating antiretroviral therapy in people diagnosed with human immunodeficiency virus: the CAPRA research programme – Programme Grants for Applied Research (free)

 


Research: Preoperative Physiotherapy for the Prevention of Respiratory Complications After Upper Abdominal Surgery

26 Jan, 2018 | 00:37h | UTC

Preoperative physiotherapy for the prevention of respiratory complications after upper abdominal surgery: pragmatic, double blinded, multicentre randomised controlled trial – The BMJ (free)

Commentaries: Pre-surgery breathing physio halves risk of complications – OnMedica (free) AND Respiratory Training Before Surgery Significantly Reduces Risk of Postoperative Lung Complications – Medindia (free) AND Breath Training Before Surgery Halves Postoperative Pneumonia Risk – Medscape (free registration required)

 


Research: Cloning of Macaque Monkeys

26 Jan, 2018 | 00:38h | UTC

Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer – Cell (free)

Commentaries: These monkey twins are the first primate clones made by the method that developed Dolly – Science (free) AND First monkeys cloned with technique that made Dolly the sheep – Nature (free) AND How afraid of human cloning should we be? – The Guardian (free)

 


Meta-Analysis: Risks and Benefits Associated with Cesarean Delivery for Mother, Baby, and Subsequent Pregnancies

26 Jan, 2018 | 00:33h | UTC

Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: Systematic review and meta-analysis – PLOS Medicine (free)

Commentaries: Caesarean section versus natural birth – an obstetrician examines a new review  – The Conversation (free) AND Expert reaction to review paper looking at long-term risks and benefits of caesarean sections – Science Media Centre (free) AND C-sections linked to long-term risks and benefits – PLOS, via EurekAlert (free) AND Long-term risks and benefits of C-section revealed – Medical News Today (free)

“As a scientist, I can appreciate the effort made in conducting a systematic review on the topic, but as an obstetrician I worry that the results can be over-interpreted by patients – not to mention obstetricians and midwives – and caesarean section “marketed” as a safe way to avoid pelvic floor problems”. (from The Conversation)

 


Research: Within Country Inequalities in Caesarean Section Rates

26 Jan, 2018 | 00:35h | UTC

Within country inequalities in caesarean section rates: observational study of 72 low and middle income countries – The BMJ (free)

Commentaries: Substantial inequalities in cesarean births persist in many countries – MedicalXpress (free) AND Global C-Section Rates on the Rise – MedPage Today (free)

 


International Technical Guidance on Sexuality Education

26 Jan, 2018 | 00:28h | UTC

International technical guidance on sexuality education: An evidence-informed approach – UNESCO (free PDF)

News release: UN urges Comprehensive Approach to Sexuality Education – UNESCO (free)

Commentary: UN issues more progressive guidelines on sex education – Devex (free)

 


Research: Association of Resting Heart Rate and Temporal Changes in Heart Rate With Cardiovascular Outcomes

26 Jan, 2018 | 00:29h | UTC

Association of Resting Heart Rate and Temporal Changes in Heart Rate With Outcomes in Participants of the Atherosclerosis Risk in Communities Study – JAMA Cardiology (free)

Commentaries: Heart Rate Changes Over Time Hint at Higher Cardiovascular Risk – TCTMD (free) AND Increasing Heart Rate Over Time May Predict CV Events – MedPage Today (free registration required)

 


Meta-Analysis: Just One Cigarette a Day Seriously Elevates Cardiovascular Risk

26 Jan, 2018 | 00:24h | UTC

Low cigarette consumption and risk of coronary heart disease and stroke: meta-analysis of 141 cohort studies in 55 study reports – The BMJ (free)

Editorial: Just one cigarette a day seriously elevates cardiovascular risk (free)

Commentaries: CHD and stroke risk seriously elevated with just one daily cigarette – OnMedica (free) AND Smoking Even One Cigarette a Day Raises Cardiovascular Risk – Medscape (free registration required) AND Smoking Just One Cigarette a Day Carries Substantial Risks – Physician’s First Watch (free)

 


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