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Daily Archives: November 5, 2017

Guideline: Familial hypercholesterolaemia

5 Nov, 2017 | 20:37h | UTC

Familial hypercholesterolaemia: identification and management – NICE Guideline (free)

News release: Inherited risk of high cholesterol should be identified and treated as early as possible, NICE says in updated guidance (free)

 


Research: Percutaneous coronary intervention in stable angina (ORBITA)

5 Nov, 2017 | 20:39h | UTC

Percutaneous coronary intervention in stable angina (ORBITA): a double-blind, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Small Trial Raises Big Concerns That PCI In Stable Angina Is Just A Placebo – Cardiobrief (free) AND Diving Deep Into The ORBITA Trial – Cardiobrief (free) AND ‘Unbelievable’: Heart Stents Fail to Ease Chest Pain – The New York Times (10 articles per month are free) AND ORBITA: PCI Offers No Symptom Improvement Over Sham Procedure – TCTMD (free)

 


Report: Cancer incidence and mortality among young adults aged 20–39 years worldwide in 2012

5 Nov, 2017 | 20:35h | UTC

Cancer incidence and mortality among young adults aged 20–39 years worldwide in 2012: a population-based study – The Lancet Oncology (free)

Commentaries: Reducing the global cancer burden among young adults – The Lancet Oncology (free) AND Global burden of cancer among young adults aged 20–39 years – eCancer News (free) AND Cancer in Young Adults Disproportionately Affects Women – Medical Research (free)

 


Research: Balanced Crystalloids vs Saline for Critically Ill Adults

5 Nov, 2017 | 20:38h | UTC

Balanced Crystalloids vs Saline for Critically Ill Adults – American College of Chest Physicians Annual Meeting (free abstract)

Related Study: Balanced Crystalloids vs Saline for Noncritically Ill Adults in the Emergency Department – American College of Chest Physicians Annual Meeting (free abstract)

Commentaries: Landmark Trials Deliver Evidence to Rethink Saline Use – Medscape (free registration required) AND Saline on the Ropes? Studies find balanced crystalloid fluids safer – MedPage Today (free registration required)

 


Guideline: Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke

5 Nov, 2017 | 20:36h | UTC

Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association (free PDF)

Commentary: Intracranial Hemorrhage After Stroke Thrombolysis: More Questions Than Answers (free)

Top Ten Things to Know: Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke (free PDF)

Slide Set: Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in AIS (free PDF)

Related AHA/ASA Guidelines: Guidelines for the Early Management of Patients With Acute Ischemic Stroke (free) AND Guidelines for the Management of Spontaneous Intracerebral Hemorrhage (free)

 


A ‘smart’ approach to performance drugs

5 Nov, 2017 | 20:35h | UTC

A ‘smart’ approach to performance drugs – ACP Internist (free)

Related: Growing use of smart drugs by students could be a recipe for disaster – The Conversation (free) AND Brain Hackers Seeking Peak Performance Use Risky Chemical Cocktails: “Smart drugs” are not clinically proven and could be dangerous – Scientific American (free) AND Universities must do more to tackle use of smart drugs, say experts – The Guardian (free) AND Tweaking brains with ‘smart drugs’ to get ahead in Silicon Valley – The Washington Post (free) AND Professors take same ‘smart drugs’ as students to keep up with workloads, claims academic – Independent (free)

 


Using Visual Abstracts to Disseminate Scientific Research

5 Nov, 2017 | 20:34h | UTC

Seeing is Believing: Using Visual Abstracts to Disseminate Scientific Research – The American Journal of Gastroenterology (free)

 


Untreatable Gonorrhea Is Rapidly Spreading. Here’s What You Need to Know

5 Nov, 2017 | 20:31h | UTC

Untreatable Gonorrhea Is Rapidly Spreading. Here’s What You Need to Know – TIME Health (free)

 


Australia ends insurance subsidies for naturopathy, homeopathy, and more

5 Nov, 2017 | 20:32h | UTC

Australia ends insurance subsidies for naturopathy, homeopathy, and more – Science-Based Medicine (free)

 


Opinion: Drug company sales reps should be banned from hospitals

5 Nov, 2017 | 20:33h | UTC

Drug company sales reps should be banned from hospitals – STAT (free)

 


Guideline: The diagnosis and management of nonalcoholic fatty liver disease

5 Nov, 2017 | 20:29h | UTC

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases – Hepatology (free)

 


Research: Adolescent Childbirth Is Associated With Greater Framingham Risk Scores for Cardiovascular Disease

5 Nov, 2017 | 20:30h | UTC

Adolescent Childbirth Is Associated With Greater Framingham Risk Scores for Cardiovascular Disease Among Participants of the IMIAS (International Mobility in Aging Study) – Journal of The American Heart Association (free)

News release: Teen childbirth linked to increased risk for heart disease (free)

Commentaries: Teen childbirth linked to increased cardiovascular risk decades later – Cardiovascular Business (free) AND Study finds link between increased cardiovascular diseases and teen childbirth – News Medical (free)

 


Guideline – Glaucoma: diagnosis and management

5 Nov, 2017 | 20:12h | UTC

Glaucoma: diagnosis and management – NICE Guideline (free)

News release: People at a low risk of developing glaucoma can avoid unnecessary referral, says NICE (free)

 


Guideline: The Care of Children With Congenital Heart Disease in Their Primary Medical Home

5 Nov, 2017 | 20:29h | UTC

The Care of Children With Congenital Heart Disease in Their Primary Medical Home – Pediatrics (free)

 


Research: Mortality lower with prolonged vs. short-term IV infusion of antipseudomonal beta-lactams

5 Nov, 2017 | 20:08h | UTC

Mortality lower with prolonged vs. short-term IV infusion of antipseudomonal beta-lactams – ACP Hospitalist (free)

Original article: Prolonged versus short-term intravenous infusion of antipseudomonal β-lactams for patients with sepsis: a systematic review and meta-analysis of randomised trials – The Lancet Infectious Diseases (link to abstract – $ for full-text)

 


Overdiagnosis and disease labels: the case of polycystic ovary syndrome

5 Nov, 2017 | 20:11h | UTC

Overdiagnosis and disease labels: the case of polycystic ovary syndrome – STAT (free)

Related: Are expanding disease definitions unnecessarily labelling women with polycystic ovary syndrome? – The BMJ (link to summary – $ for full-text)

 


Bacteria Can Evolve Resistance to Drugs Before Those Drugs Are Used

5 Nov, 2017 | 20:10h | UTC

Bacteria Can Evolve Resistance to Drugs Before Those Drugs Are Used – The Atlantic (free)

 


Aspirin reduces a woman’s chance of developing pre-eclampsia in pregnancy

5 Nov, 2017 | 20:02h | UTC

Aspirin reduces a woman’s chance of developing pre-eclampsia in pregnancy – NIHR Signal (free)

Original article: Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia – New England Journal of Medicine (link to abstract – $ for full-text)

 


Updated WHO recommendation on intravenous tranexamic acid for the treatment of post-partum haemorrhage

5 Nov, 2017 | 20:08h | UTC

Updated WHO recommendation on intravenous tranexamic acid for the treatment of post-partum haemorrhage – The Lancet Global Health (free)

 


Research: Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori

5 Nov, 2017 | 19:59h | UTC

Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study – Gut (link to abstract – $ for full-text)

Commentaries: Acid reflux drug linked to more than doubled risk of stomach cancer – study – The Guardian (free) AND Gastric Cancer Risk Doubled With Long-term PPI Use – Medscape (free registration required) AND PPI Use After H. pylori Eradication Therapy Tied to Increased Risk for Gastric Cancer – Physician’s First Watch (free)

 


Vaginal cleansing before caesarean delivery reduces risk of infections

5 Nov, 2017 | 20:00h | UTC

Vaginal cleansing before caesarean delivery reduces risk of infections – NIHR signal (free)

Original article: Vaginal Cleansing Before Cesarean Delivery: A Systematic Review and Meta-analysis – Obstetrics & Gynecology (link to abstract – $ for full-text)

 


Lancet Countdown: Traking Progress on Health and Climate Change

5 Nov, 2017 | 20:00h | UTC

Lancet Countdown: Traking Progress on Health and Climate Change (free infographics, video and other resources)

Report: The Lancet Countdown on health and climate change: from 25 years of inaction to a global transformation for public health (free registration required)

Commentaries: Health impacts of climate change already felt today – Imperial College London (free) AND How Climate Change Is Already Affecting Health, Spreading Disease – NPR Goats and Soda (free) AND Climate change already bringing disease, air pollution and heatwaves – The Guardian (free) AND Climate change isn’t just hurting the planet – it’s a public health emergency – The Guardian (free)

 


Research: Maintenance therapy with proton pump inhibitors and risk of gastric cancer

5 Nov, 2017 | 19:58h | UTC

Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden – BMJ Open (free)

“Among 797 067 individuals on maintenance PPI therapy, the SIR of gastric cancer was over threefold increased (SIR=3.38, 95% CI 3.23 to 3.53)”.

 


Research: Long-term aspirin use reduces the incidence of digestive cancers by up to 47%

5 Nov, 2017 | 19:56h | UTC

25th UEG (United European Gastroenterology) Week: Long-term aspirin use reduces the incidence of digestive cancers by up to 47% (free)

Commentaries: Long-Term Aspirin Use May Reduce Cancer Risk, Study Finds – Forbes (free) AND Aspirin slashes risk of gastrointestinal cancer – Medical News Today (free)

 


Review: Point of Care Ultrasound

5 Nov, 2017 | 19:57h | UTC

Point of Care Ultrasound: An Overview – American College of Cardiology, Latest in Cardiology (free)

Related reviews: Ultrasonography in the emergency department – Critical Care (free) AND Clinically integrated multi-organ point-of-care ultrasound for undifferentiated respiratory difficulty, chest pain, or shock: a critical analytic review – Journal of Intensive Care (free) AND Common pitfalls in point-of-care ultrasound: a practical guide for emergency and critical care physicians – Critical Ultrasound Journal (free) AND Point-of-Care Ultrasonography by Pediatric Emergency Medicine Physicians – Pediatrics (free)

 


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