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Daily Archives: September 1, 2017

Cohort Study: Association between sedentary time and mortality across levels of frailty

1 Sep, 2017 | 20:57h | UTC

Association between sedentary time and mortality across levels of frailty – Canadian Medical Association Journal (free)

Commentary: Prolonged sitting and frailty a deadly combination – Medical News Today (free) AND Inactivity Toll Worst for Frailest Elders – Medscape (free registration required)

 


Head injuries in sport must be taken more seriously

1 Sep, 2017 | 20:50h | UTC

Head injuries in sport must be taken more seriously – Nature News (free)

“Sports organizations are only starting to understand the harm that can be inflicted by high-contact activities. Science must play its part in highlighting the problem and in aiding diagnosis”.

 


Viewpoint: Diagnostic Errors and Diagnostic Calibration

1 Sep, 2017 | 20:54h | UTC

Diagnostic Errors and Diagnostic Calibration – JAMA (free)

 


Review: Perioperative use of immunosuppressive medications in patients with Crohn’s disease in the new “biological era”

1 Sep, 2017 | 20:48h | UTC

Perioperative use of immunosuppressive medications in patients with Crohn’s disease in the new “biological era” – Gastroenterology Report (free)

Source: Critical Care Reviews Newsletter

 


Review: Angioedema: An Interdisciplinary Emergency

1 Sep, 2017 | 20:46h | UTC

Angioedema: An Interdisciplinary Emergency – Deutsches Ärzteblatt international (free)

Source: Critical Care Reviews Newsletter

 


Consensus paper: The role of open abdomen in non-trauma patient

1 Sep, 2017 | 20:43h | UTC

The role of open abdomen in non-trauma patient: WSES Consensus Paper – World Journal of Emergency Surgery (free)

Source: Critical Care Reviews Newsletter

 


Study: Risk of being convicted of theft and other crimes in anorexia nervosa and bulimia nervosa

1 Sep, 2017 | 19:07h | UTC

Risk of being convicted of theft and other crimes in anorexia nervosa and bulimia nervosa: A prospective cohort study in a Swedish female population – International Journal of Eating Disorders (link to abstract – $ for full-text)

Commentary: Eating disorders linked to history of theft – Reuters (free)

 


Review: Variceal bleeding in cirrhotic patients

1 Sep, 2017 | 20:38h | UTC

Variceal bleeding in cirrhotic patients – Gastroenterology Report (free)

Source: Critical Care Reviews Newsletter

 


In health push, Singapore gets soda makers to cut sugar content

1 Sep, 2017 | 19:02h | UTC

In health push, Singapore gets soda makers to cut sugar content – Reuters (free)

See related articles on fiscal policies to reduce sugar consumption in our June 8th issue (see #4) and in our April 20th issue (see #1)

 


Review: New-onset acute thrombocytopenia in hospitalized patients

1 Sep, 2017 | 20:40h | UTC

New-onset acute thrombocytopenia in hospitalized patients: pathophysiology and diagnostic approach – Journal of Community Hospital Internal Medicine Perspectives (free)

Source: Critical Care Reviews Newsletter

 


Review: Ileus in Adults: Pathogenesis, Investigation and Treatment

1 Sep, 2017 | 20:36h | UTC

Ileus in Adults: Pathogenesis, Investigation and Treatment – Deutsches Ärzteblatt international (free)

Source: Critical Care Reviews Newsletter

 


Guideline: Accelerated Partial Breast Irradiation

1 Sep, 2017 | 18:54h | UTC

Accelerated Partial Breast Irradiation: Executive summary for the update of an ASTRO Evidence-Based Consensus Statement (free)

See also: National Guideline Clearinghouse Summary (free)

 


Study: Corticosteroid Premedication 5 Hours Before CT Compared with a 13-Hour Oral Regimen

1 Sep, 2017 | 17:57h | UTC

Intravenous Corticosteroid Premedication Administered 5 Hours Before CT Compared with a Traditional 13-Hour Oral Regimen – Radiology (link to abstract – $ for full-text)

Source: Journal Watch ($)

“Accelerated intravenous premedication with corticosteroids beginning 5 hours before contrast-enhanced CT has a breakthrough reaction rate noninferior to that of a 13-hour oral premedication regimen”.

 


Study: Software-guided versus nurse-directed blood glucose control in critically ill patients

1 Sep, 2017 | 18:47h | UTC

Software-guided versus nurse-directed blood glucose control in critically ill patients: the LOGIC-2 multicenter randomized controlled clinical trial – Critical Care (free)

Source: Hospital Medicine Virtual Journal Club

 


Review: Prevention of Alzheimer’s Disease

1 Sep, 2017 | 17:35h | UTC

Prevention of Alzheimer’s Disease: Lessons Learned and Applied – Journal of The American Geriatrics Society (free)

Source: PracticeUpdate

 


Meta-analysis: fibrinolytic agents in patients with ST-segment elevation myocardial infarction

1 Sep, 2017 | 17:44h | UTC

Comparative efficacy and safety of reperfusion therapy with fibrinolytic agents in patients with ST-segment elevation myocardial infarction: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentary: Fibrinolytic Agents for STEMI: Meta-analysis Explores the Differences – TCTMD (free)

 


Fri, September 1 – 10 Stories of The Day!

1 Sep, 2017 | 00:42h | UTC

 

1 – Public Health Guideline: Vitamin D: supplement use in specific population groups – National Institute for Health and Care Excellence (NICE) (free)

“Only test vitamin D status if someone has symptoms of deficiency or is at very high risk”

 

2 – Drug treatment effects on outcomes in heart failure with preserved ejection fraction: a systematic review and meta-analysis – Heart (free)

Commentary: Heart Failure with Preserved Ejection Fraction: Treatments Compared – MPR (free)

Source: ACP Journal Wise ($)

This study suggests a reduction in all-cause mortality with beta-blocker therapy in patients with heart failure with preserved ejection fraction. The authors recommend further trials to confirm the benefits of beta-blockers in this patient group.

 

3 – Drug-Free Interventions to Reduce Pain or Opioid Consumption After Total Knee Arthroplasty: A Systematic Review and Meta-analysis – JAMA Surgery (free)

Commentaries: Acupuncture, Electrotherapy after Knee Replacement Associated with Reduced and Delayed Opioid Use – The JAMA Network (free) AND Electrotherapy, Acupuncture Tied to Less Opioid Use After Knee Arthroscopy – Medscape (free registration required) AND Meta-Analysis: Electrotherapy, Acupuncture May Help Reduce Opioid Use After Knee Arthroplasty – Physician’s First Watch (free)

 

4 – Original articles: Cost-Effectiveness of Intensive versus Standard Blood-Pressure Control – New England Journal of Medicine (link to abstract – $ for full-text) AND Effect of Intensive Blood-Pressure Treatment on Patient-Reported Outcomes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Analyses from SPRINT examine cost-effectiveness, patient-reported outcomes with intensive BP control – ACP Internist (free) AND Intensive BP Management Well Tolerated, Cost-effective: SPRINT – Medscape (free registration required) AND Can SPRINT Be Used To Inform Hypertension Treatment? – Cardiobrief (free)

Be sure to measure the patient’s blood pressure in the same way it was done in the SPRINT trial before adopting this study results in clinical practice (see Cardiobrief commentary)

 

5 – Natural History and Tumor Volume Kinetics of Papillary Thyroid Cancers During Active Surveillance – JAMA Otolaryngology Head & Neck Surgery (free for a week)

Author interview: Natural History and Tumor Volume Kinetics of Papillary Thyroid Cancers (free audio)

Commentaries: Findings Support Use of Active Surveillance for Low-Risk Papillary Thyroid Cancer – The JAMA Network (free) AND Many People Can Delay Treatment For Thyroid Cancer, Study Finds – NPR (free)

 

6 – How should we deal with non-culprit lesions during a STEMI? A mid-night conundrum – Evidently Cochrane (free)

Original article: Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (link to abstract – $ for full-text)

 

7 – Preventing Teen Suicide: What Does the Evidence Shows – The New York Times (10 articles per month are free)

Related Guideline: Preventing Suicide: A Technical Package of Policy, Programs, and Practices – Centers for Disease Control and Prevention (free PDF)

 

8 – Low molecular weight heparin for prevention of venous thromboembolism in patients with lower-limb immobilization – Cochrane Library (link to abstract – $ for full-text)

“Moderate-quality evidence showed that the use of LMWH in outpatients reduced DVT when immobilization of the lower limb was required, when compared with no prophylaxis or placebo”. 

 

9 – Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006) – The Lancet (link to abstract – $ for full-text)

Commentary: Pembrolizumab Prolongs Overall Survival Compared With Ipilimumab in Melanoma – Cancer Therapy Advisor (free)

Source: Richard Lehman’s journal review (free)

 

10 – Impact of Obesity on Intensive Care Unit Resource Utilization After Cardiac Operations – The Annals of Thoracic Surgery (link to abstract – $ for full-text)

Commentaries: Obese cardiac patients a drain on ICU resources – Cardiovascular Business (free) AND Obese Cardiac Surgery Patients a Burden on ICU Resources – TCTMD (free) AND Post–Cardiac Surgery ICU Usage Rises With Increasing Obesity – Medscape (free registration required)

 


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