Daily Archives: August 31, 2017
“Do “bundled payments” truly produce better healthcare?
31 Aug, 2017 | 21:11h | UTCThe Battle Of The Bundle: Lessons From My Mother’s Partial Hip Replacement – Health Affairs (free) (RT @OUPMedicine see Tweet)
Studies: Intensive versus Standard Blood-Pressure Control
31 Aug, 2017 | 20:35h | UTCOriginal articles: Cost-Effectiveness of Intensive versus Standard Blood-Pressure Control – New England Journal of Medicine (link to abstract – $ for full-text) AND Effect of Intensive Blood-Pressure Treatment on Patient-Reported Outcomes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Analyses from SPRINT examine cost-effectiveness, patient-reported outcomes with intensive BP control – ACP Internist (free) AND Intensive BP Management Well Tolerated, Cost-effective: SPRINT – Medscape (free registration required) AND Can SPRINT Be Used To Inform Hypertension Treatment? – Cardiobrief (free)
Be sure to measure the patient’s blood pressure in the same way it was done in the SPRINT trial before adopting this results to clinical practice (see Cardiobrief commentary)
Study: Active Surveillance for Low-Risk Papillary Thyroid Cancer May be Safe
31 Aug, 2017 | 22:34h | UTCNatural History and Tumor Volume Kinetics of Papillary Thyroid Cancers During Active Surveillance – JAMA Otolaryngology Head & Neck Surgery (free for a week)
Author interview audio: Natural History and Tumor Volume Kinetics of Papillary Thyroid Cancers (free)
Commentaries: Findings Support Use of Active Surveillance for Low-Risk Papillary Thyroid Cancer – The JAMA Network (free) AND Many People Can Delay Treatment For Thyroid Cancer, Study Finds – NPR (free)
Systematic Review: Pharmacotherapy for hypertension in adults aged 18 to 59 years
31 Aug, 2017 | 20:44h | UTCPharmacotherapy for hypertension in adults aged 18 to 59 years – Cochrane Library (link to abstract – $ for full-text)
Commentary: Antihypertensive Tx Analyzed in Younger, Predominantly Healthy Adults – MPR (free)
Preventing Teen Suicide: What Does the Evidence Shows
31 Aug, 2017 | 21:06h | UTCPreventing Teen Suicide: What Does the Evidence Shows – The New York Times (10 articles per month are free)
Related Guideline: Preventing Suicide: A Technical Package of Policy, Programs, and Practices – Centers for Disease Control and Prevention (free PDF)
Guidelines for the diagnosis and treatment of postmenopausal osteoporosis
31 Aug, 2017 | 19:27h | UTC
Study: Pembrolizumab versus ipilimumab for advanced melanoma
31 Aug, 2017 | 20:31h | UTCPembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006) – The Lancet (link to abstract – $ for full-text)
Commentary: Pembrolizumab Prolongs Overall Survival Compared With Ipilimumab in Melanoma – Cancer Therapy Advisor (free)
Source: Richard Lehman’s journal review (free)
Meta-analysis: Drugs in heart failure with preserved ejection fraction
31 Aug, 2017 | 20:33h | UTCCommentary: Heart Failure with Preserved Ejection Fraction: Treatments Compared – MPR (free)
Source: ACP Journal Wise ($)
This study suggests a reduction in all-cause mortality with beta-blocker therapy in patients with heart failure with preserved ejection fraction. The authors recommend further trials to confirm the benefits of beta-blockers in this patient group.
Guideline: Vitamin D Supplementation
31 Aug, 2017 | 19:42h | UTCPublic Health Guideline: Vitamin D: supplement use in specific population groups – National Institute for Health and Care Excellence (NICE) (free)
“Only test vitamin D status if someone has symptoms of deficiency or is at very high risk”
Employers Accelerate Move To Value-Based Care In 2018
31 Aug, 2017 | 16:39h | UTCEmployers Accelerate Move To Value-Based Care In 2018 – Forbes (free)
Review: Acute aortic dissection: pathogenesis, risk factors and diagnosis
31 Aug, 2017 | 20:28h | UTCAcute aortic dissection: pathogenesis, risk factors and diagnosis – Swiss Medical Weekly (free)
Review article: hepatitis E—a concise review of virology, epidemiology, clinical presentation and therapy
31 Aug, 2017 | 16:44h | UTCReview article: hepatitis E—a concise review of virology, epidemiology, clinical presentation and therapy – Alimentary Pharmacology and Therapeutics (free)
Source: Medscape
Study: Impact of Obesity on Intensive Care Unit Resource Utilization After Cardiac Operations
31 Aug, 2017 | 16:31h | UTCImpact of Obesity on Intensive Care Unit Resource Utilization After Cardiac Operations – The Annals of Thoracic Surgery (link to abstract – $ for full-text)
Commentaries: Obese cardiac patients a drain on ICU resources – Cardiovascular Business (free) AND Obese Cardiac Surgery Patients a Burden on ICU Resources – TCTMD (free) AND Post–Cardiac Surgery ICU Usage Rises With Increasing Obesity – Medscape (free registration required)
Meta-analysis: Drug-Free Interventions to Reduce Pain After Total Knee Arthroplasty
31 Aug, 2017 | 15:43h | UTCCommentaries: Acupuncture, Electrotherapy after Knee Replacement Associated with Reduced and Delayed Opioid Use – The JAMA Network (free) AND Electrotherapy, Acupuncture Tied to Less Opioid Use After Knee Arthroscopy – Medscape (free registration required) AND Meta-Analysis: Electrotherapy, Acupuncture May Help Reduce Opioid Use After Knee Arthroplasty – Physician’s First Watch (free)
Systematic Review: Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease
31 Aug, 2017 | 16:11h | UTCOriginal article: Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (link to abstract – $ for full-text)
Review: Chest CT Signs in Pulmonary Disease
31 Aug, 2017 | 15:19h | UTCChest CT Signs in Pulmonary Disease: A Pictorial Review – Chest (free)
Source: Critical Care Review Newsletter (free)
Study: effects of probiotic and peanut oral immunotherapy for peanut allergy
31 Aug, 2017 | 15:53h | UTCLong-term clinical and immunological effects of probiotic and peanut oral immunotherapy after treatment cessation: 4-year follow-up of a randomised, double-blind, placebo-controlled trial – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)
Commentaries: Benefits of Immunotherapy-Probiotic Combo for Peanut Allergy Sustained at 4 Years – Physician’s First Watch (free) AND Peanut Allergy: Is Oral Immunotherapy With Probiotic a Cure? – Medscape (free registration required) AND Peanut Allergy Tx Efficacy Examined in 4-Year Follow-Up Study – MPR (free)
Study: Comparison of recommendations for screening mammography
31 Aug, 2017 | 15:20h | UTCComparison of recommendations for screening mammography using CISNET models – Cancer (link to abstract – $ for full-text)
Commentaries: Three questions to ask about calls to widen breast cancer screening – The Conversation (free) AND Comparison of Screening Recommendations for Mammography – ASCO Post (free)
Canadian Task Force on Preventive Health Care: Risks & Benefits, Age 40–49 (free) AND Risks & Benefits, Age 50–69 (free) AND Risks & Benefits, Age 70–74 (free) AND Full Guideline and Resources (free)
This article had a lot of attention from the media and suggests an annual screening starting at age 40 would prevent more breast cancer deaths. But screening has potential harms. For a clearer picture of the benefits and harms of screening in this context have a look at The Conversation commentary above and the infographics from the Canadian Task Force.
Guideline: Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer
31 Aug, 2017 | 15:08h | UTC
Study: Cognitive Function in a Randomized Trial of Evolocumab
31 Aug, 2017 | 15:35h | UTCCognitive Function in a Randomized Trial of Evolocumab – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Cholesterol-Lowering Drug Evolocumab Doesn’t Seem to Impair Cognition – Physician’s First Watch (free)
“The authors caution that most people take cholesterol-lowering medications for decades, and this was a much shorter follow-up period” (from Physician’s First Watch).
Thu, August 31 – 10 Stories of The Day!
31 Aug, 2017 | 00:04h | UTC
1 – Comparison of recommendations for screening mammography using CISNET models – Cancer (link to abstract – $ for full-text)
Commentaries: Three questions to ask about calls to widen breast cancer screening – The Conversation (free) AND Comparison of Screening Recommendations for Mammography – ASCO Post (free)
Canadian Task Force on Preventive Health Care: Risks & Benefits, Age 40–49 (free) AND Risks & Benefits, Age 50–69 (free) AND Risks & Benefits, Age 70–74 (free) AND Full Guideline and Resources (free)
This article had a lot of attention from the media and suggests an annual screening starting at age 40 would prevent more breast cancer deaths. But screening has potential harms. For a clearer picture of the benefits and harms of screening in this context have a look at The Conversation commentary above and the infographics from the Canadian Task Force.
2 – History of breast feeding and risk of incident endometriosis: prospective cohort study – The BMJ (free)
Commentaries: Breast-Feeding Associated with Reduced Endometriosis Risk – Physician’s First Watch (free) AND Breast-Feeding May Lower Risk of Endometriosis – The New York Times (10 articles per month are free)
3 – Sleep architecture and the risk of incident dementia in the community – Neurology (link to abstract – $ for full-text)
Commentaries: Lack of REM sleep may lead to higher risk for dementia – Boston University School of Medicine, via EurekAlert (free) AND Less REM Sleep May Significantly Boost Dementia Risk – Medscape (free registration required) AND Dreaming may keep dementia at bay – Medical News Today (free) AND Lack of REM sleep tied to increased risk of dementia – Reuters (free)
4 – Association of Sleep-Disordered Breathing With Cognitive Function and Risk of Cognitive Impairment: A Systematic Review Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)
Commentaries: Breathing Disorders During Sleep Tied to Cognitive Issues – MedPage Today (free registration required) AND Sleep-Disordered Breathing Raises Risk for Cognitive Decline – Medscape (free registration required)
This meta-analysis of observational studies suggests a possible association. Further studies are needed to examine whether the treatment of this condition can help in the prevention of dementia and in improvement of cognition.
5 – Chest CT Signs in Pulmonary Disease: A Pictorial Review – Chest (free)
Source: Critical Care Review Newsletter (free)
6 – Viewpoint: Management of Parkinson Disease in 2017: Personalized Approaches for Patient-Specific Needs – JAMA (free)
7 – Chronic cough postacute respiratory illness in children: a cohort study – Archives of Disease in Childhood (link to abstract – $ for full-text)
Commentary: Kids often have a chronic cough after respiratory illness – Reuters (free)
8 – Medical News & Perspectives: Medical Students Fall Short on Blood Pressure Check Challenge – JAMA (free)
Original Article: Medical students and measuring blood pressure: Results from the American Medical Association Blood Pressure Check Challenge – The Journal of Clinical Hypertension (free)
“Only 1 out of 159 medical students correctly performed all 11 elements in a BP check challenge w simulated patients” (RT @JAMA_current see Tweet)
9 – #ESCCongress – Clopidogrel or ticagrelor in acute coronary syndrome patients treated with newer-generation drug-eluting stents: CHANGE DAPT – EuroIntervention (link to abstract – $ for full-text)
Commentaries: Rethinking dual antiplatelet guidelines in acute coronary syndrome? (CHANGE-DAPT) – ESC Press Releases (free) AND Ticagrelor for DAPT Again Questioned in Current Era of PCI for ACS: CHANGE DAPT – Medscape (free registration required) AND CHANGE DAPT: Study Contests Benefit of Ticagrelor Over Clopidogrel After PCI in ACS – TCTMD (free)
10 – Resistance training may prevent obese older people becoming frail when losing weight – NIHR Signal (free)
Original article: Aerobic or Resistance Exercise, or Both, in Dieting Obese Older Adults – New England Journal of Medicine (link to abstract – $ for full-text) AND Video Summary: Exercise and Dieting in Obese Older Adults (free)
Practice guidelines: management of cervical cancer
31 Aug, 2017 | 15:07h | UTC
Guideline: Brachytherapy for Patients With Prostate Cancer
31 Aug, 2017 | 15:06h | UTC