Daily Archives: August 29, 2017

Iron chelation with oral Deferasirox (instead of injected deferoxamine) may offer an important treatment option for people with thalassaemia and secondary iron overload.

Systematic Review: Benefits and harms of sugammadex versus neostigmine in reversing induced paralysis

29 Aug, 2017 | 14:59h | UTC

Benefits and harms of sugammadex versus neostigmine in reversing induced paralysis – Cochrane Library (free)

Full review: Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults – Cochrane Library (link to abstract – $ for full-text)

“sugammadex may work more rapidly than neostigmine to reverse neuromuscular block in adults” (RT @CochraneUK see Tweet)

Study: Community-acquired Pneumonia Visualized on Computed Tomography but Not Chest X-Ray

29 Aug, 2017 | 14:54h | UTC

Community-acquired Pneumonia Visualized on Computed Tomography but Not Chest X-Ray: Pathogens, Severity, and Clinical Outcomes – Chest (link to abstract – $ for full-text)

Source: Hospital Medicine Virtual Journal Club (free resource to find articles of interest)

“Adults hospitalized with CAP who had radiologic evidence of pneumonia on CT but not concurrent CXR had similar pathogens, disease severity, and outcomes compared with patients who had signs of pneumonia on CXR”.

Novel Statistical Methods: Bayesian Analysis

29 Aug, 2017 | 14:55h | UTC

Novel Statistical Methods: Bayesian Analysis: A Practical Approach to Interpret Clinical Trials and Create Clinical Practice Guidelines – Circulation (free)

Editor’s Perspective: When Bayes Comes to Town (free)

Guideline: Osteoarthritis of the Knee Clical Care Standard

29 Aug, 2017 | 15:00h | UTC

Osteoarthritis of the Knee Clical Care Standard – Australian Commission on Safety and Quality in Health Care (PDF Guideline and other resources)

Source: Research Review Australia (free resource to find articles of interest)

1 – #ESCCongress – Oxygen Therapy in Suspected Acute Myocardial Infarction – New England Journal of Medicine (free)

Editorial: Is Oxygen Therapy Beneficial in Acute Myocardial Infarction? Simple Question, Complicated Mechanism, Simple Answer (free)

Commentaries: Oxygen therapy does not improve survival in patients with heart attack symptoms (DETO2X-AMI) – ESC Press Releases (free) AND Supplemental Oxygen Provides No Benefit to Patients With Suspected MI: DETO2X-AMI – TCTMD (free) AND Suspected MI and Normal Oxygen Saturation? Don’t Bother with Supplemental Oxygen – Physician’s First Watch (free)

2 – #ESCCongress – Population screening and intervention for vascular disease in Danish men (VIVA): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)

3 – #ESCCongress – PATHWAY-2 uncovers main cause of drug-resistant hypertension, finds old drugs work best – ESC Press Releases (free) (the results have not been published yet)

Commentary: Prevention And Treatment of Hypertension With Algorithm based therapY-2 – PATHWAY-2 – American College of Cardiology, Latest in Cardiology (free)

4 – #ESCCongress – Bag-mask ventilation fails to improve on endotracheal intubation in cardiac arrest (CAAM) – ESC Press Releases (free) (the results have not been published yet)

Commentary: CAAM: Is Bag-Mask Ventilation Superior to ETI During CPR? – American College of Cardiology, Latest in Cardiology (free)

5 – #ESCCongress – Closure of left atrial appendage during heart surgery protects the brain (LAACS) – ESC Press Releases (free) (the results have not been published yet)

Commentary: LAACS: LAA Closure May Protect Against Long-Term Cerebral Ischemic Events – American College of Cardiology, Latest in Cardiology (free)

6 – #ESCCongress – Risk factor driven upstream atrial fibrillation therapy improves sinus rhythm maintenance (RACE 3) – ESC Press Releases (free) (the results have not been published yet)

Commentaries: Broad, Early AF Risk-Factor Intervention Preserves Sinus Rhythm: RACE-3 – Medscape (free registration required) AND Routine vs. Aggressive upstream rhythm Control for prevention of Early persistent atrial fibrillation in heart failure study – RACE 3 – American College of Cardiology, Latest in Cardiology (free)

7 – #ESCCongress – The Prognostic Value of Coronary Artery Calcium in the PROMISE Study – Circulation (free PDF)

Editorial: Computed Tomography or Functional Stress Testing for the Prediction of Risk: Can I Have My Cake and Eat It? (free PDF)

Commentary: Prospective Multicenter Imaging Study for Evaluation of Chest Pain – PROMISE – American College of Cardiology, Latest in Cardiology (free)

8 – Why developing countries must improve primary care – The Economist (free) (RT @AnjaNitzscheB see Tweet)

“The changing burden of disease requires a better approach to keeping people healthy”

9 – Necrotizing pancreatitis: Diagnose, treat, consult – Cleveland Clinic Journal of Medicine (free)

Source: Hospital Medicine Virtual Journal Club (free resource to find articles of interest)

10 – Using mesh does not improve results in vaginal prolapse surgery – NIHR Signal (free)

Original article: Mesh, graft, or standard repair for women having primary transvaginal anterior or posterior compartment prolapse surgery: two parallel-group, multicentre, randomised, controlled trials (PROSPECT) – The Lancet (free) AND Commentary: Mesh, graft, or standard repair for prolapse surgery? – The Lancet (free)

“About 12% of vaginal prolapse patients had complications from surgery using mesh” (RT @NIHR_DC see Tweet)

Meta-analysis: Effectiveness of Light Therapy in Cognitively Impaired Persons

29 Aug, 2017 | 14:52h | UTC

Effectiveness of Light Therapy in Cognitively Impaired Persons: A Metaanalysis of Randomized Controlled Trials – Journal of The American Geriatric Society (link to abstract – $ for full-text)

Source: ACP Journal Wise ($)

#ESCCongress – Study: Oxygen Therapy in Suspected Acute Myocardial Infarction

#ESCCongress – Study: Screening for vascular disease saves one life for every 169 patients assessed

#ESCCongress – Study: drug-resistant hypertension – old drugs work best

#ESCCongress – Study: Bag-mask ventilation fails to improve on endotracheal intubation in cardiac arrest

#ESCCongress – Study: Risk factor driven upstream atrial fibrillation therapy improves sinus rhythm maintenance

#ESCCongress – Study: The Prognostic Value of Coronary Artery Calcium

#ESCCongress – Study: Closure of left atrial appendage during heart surgery protects the brain

Why developing countries must improve primary care

Guidelines for emergency repair of complicated abdominal wall hernias

Management Guidelines for Metal-on-metal Hip Resurfacing Arthroplasty

Guidelines for the diagnosis of fibromyalgia

Review: Necrotizing pancreatitis

Systematic Review: Topical Antibiotics for Impetigo

Guideline: diagnosis and treatment of osteoporosis in men

Clinical practice guidelines for congenital hyperinsulinism

Systematic Review: Deferasirox for managing iron overload in people with thalassaemia

Systematic Review: Benefits and harms of sugammadex versus neostigmine in reversing induced paralysis

Study: Community-acquired Pneumonia Visualized on Computed Tomography but Not Chest X-Ray

Novel Statistical Methods: Bayesian Analysis

Guideline: Osteoarthritis of the Knee Clical Care Standard

Review: DRESS: What does the emergency physician need to know?

What We Are Watching—Top Global Infectious Disease Threats

Tue, August 29 – 10 Stories of The Day!

Meta-analysis: Effectiveness of Light Therapy in Cognitively Impaired Persons

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