Daily Archives: May 25, 2017
Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease
25 May, 2017 | 14:55h | UTCRecommended: New QRISK-3 2017 Calculator (free)
QRISK-3 risk prediction model was developed with data from 7.89 million patients in the derivation cohort and 2.67 million patients in the validation cohort. QRISK-3 includes more factors than QRISK2 to help enable doctors to identify those at most risk of heart disease and stroke. New risk factors include: 1) Chronic kidney disease, which now includes stage 3 CKD; 2) Migraine; 3) Use of corticosteroids; 4) Systemic lupus erythematosus (SLE); 5) Use of atypical antipsychotics; 6) Severe mental illness; 7) Erectile dysfunction; 8) and Systolic blood pressure variability.
Effect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis
25 May, 2017 | 14:53h | UTCEffect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis: A Randomized Clinical Trial – JAMA (Link to abstract – $ for full-text)
Commentaries: Adding Anti-MRSA to Cephalexin No Better for Simple Cellulitis – Medscape (free registration required) AND Adding TMP/SMX to Cephalexin May Not Boost Cure Rate in Uncomplicated Cellulitis – Physician’s First Watch (free)
Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women
25 May, 2017 | 14:52h | UTCOil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Study confirms ‘flushing’ blocked fallopian tubes can improve fertility and reduce need for IVF – The Conversation (free) AND Can poppyseed oil help infertile couples conceive? – STAT News (free)
Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation
25 May, 2017 | 14:54h | UTCStroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation (2017) – Royal College of Paediatrics and Child Health(free) (RT @bmj_latest see Tweet)
News release: New guidelines launched to help healthcare professionals and parents spot the signs of stroke in children (free)
Other resources: Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation (2017) (free)
The lap band for weight loss is a tale of medicine gone wrong
25 May, 2017 | 15:02h | UTCThe lap band for weight loss is a tale of medicine gone wrong – VOX (free)
See also a recent study showing high complication rates of laparoscopic gastric band surgeries in our May 23rd issue (see #7)
Very strict blood sugar control in critically ill children provides no benefit
25 May, 2017 | 14:50h | UTCVery strict blood sugar control in critically ill children provides no benefit – NIHR Signal (free)
Original article (link to abstract – $ for full-text): Tight Glycemic Control in Critically Ill Children – New England Journal of Medicine (free)
Effect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery
25 May, 2017 | 14:50h | UTCEffect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery: A Cluster Randomized Clinical Trial – JAMA Surgery (free) (RT @PreetiNMalani see Tweet)
Commentary: Anti-delirium strategy reduces after-surgery confusion in elderly – Reuters Health (free)
Multicomponent nonpharmacologic interventions, including orienting communications, oral and nutritional assistance, and early mobilization reduced postoperative delirium by 56% and length of stay by 2 days.
Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease
25 May, 2017 | 14:46h | UTCComplete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (link to abstract – $ for full-text) (RT @Gas_Craic see Tweet)
“Compared with culprit-only intervention, the complete revascularisation strategy may be superior due to lower proportions of long-term cardiovascular mortality, long-term revascularisation, and long-term non-fatal myocardial infarction, but these findings are based on evidence of very low quality”
Human papillomavirus vaccines: WHO position paper
25 May, 2017 | 14:48h | UTC“WHO update on HPV vaccine. Short summary – it’s very safe, very effective, widespread implementation recommended” (RT @michaelgheadsee Tweet)
Factors Associated with Pediatric Mortality from Motor Vehicle Crashes
25 May, 2017 | 14:47h | UTCCommentaries: 43 Percent Of Children Who Died From Car Crashes Were Improperly Restrained – NPR Health News (free)
Thu, May 25 – 10 Medical Stories of The Day!
25 May, 2017 | 00:01h | UTC
Recommended: New QRISK-3 2017 Calculator (free)
QRISK-3 risk prediction model was developed with data from 7.89 million patients in the derivation cohort and 2.67 million patients in the validation cohort. QRISK-3 includes more factors than QRISK2 to help enable doctors to identify those at most risk of heart disease and stroke. New risk factors include: 1) Chronic kidney disease, which now includes stage 3 CKD; 2) Migraine; 3) Use of corticosteroids; 4) Systemic lupus erythematosus (SLE); 5) Use of atypical antipsychotics; 6) Severe mental illness; 7) Erectile dysfunction; 8) and Systolic blood pressure variability.
2 – Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation (2017) – Royal College of Paediatrics and Child Health (free PDF) (RT @bmj_latest see Tweet)
News release: New guidelines launched to help healthcare professionals and parents spot the signs of stroke in children (free)
Other resources: Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation (2017) (free)
3 – Effect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis: A Randomized Clinical Trial – JAMA (Link to abstract – $ for full-text)
Commentaries: Adding Anti-MRSA to Cephalexin No Better for Simple Cellulitis – Medscape (free registration required) AND Adding TMP/SMX to Cephalexin May Not Boost Cure Rate in Uncomplicated Cellulitis – Physician’s First Watch (free)
4 – Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Study confirms ‘flushing’ blocked fallopian tubes can improve fertility and reduce need for IVF – The Conversation (free) AND Can poppyseed oil help infertile couples conceive? – STAT News (free)
5 – Effect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery: A Cluster Randomized Clinical Trial – JAMA Surgery (free) (RT @PreetiNMalani see Tweet)
Commentary: Anti-delirium strategy reduces after-surgery confusion in elderly – Reuters Health (free)
Multicomponent nonpharmacologic interventions, including orienting communications, oral and nutritional assistance, and early mobilization reduced postoperative delirium by 56% and length of stay by 2 days.
6 – Very strict blood sugar control in critically ill children provides no benefit – NIHR Signal (free)
Original article (link to abstract – $ for full-text): Tight Glycemic Control in Critically Ill Children – New England Journal of Medicine (free)
“WHO update on HPV vaccine. Short summary – it’s very safe, very effective, widespread implementation recommended” (RT @michaelghead see Tweet)
Commentaries: 43 Percent Of Children Who Died From Car Crashes Were Improperly Restrained – NPR Health News (free)
9 – Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (link to abstract – $ for full-text) (RT @Gas_Craic see Tweet)
“Compared with culprit-only intervention, the complete revascularisation strategy may be superior due to lower proportions of long-term cardiovascular mortality, long-term revascularisation, and long-term non-fatal myocardial infarction, but these findings are based on evidence of very low quality”
10 – Angioedema in the emergency department: a practical guide to differential diagnosis and management – International Journal of Emergency Medicine (free) (RT @Gas_Craic see Tweet)
Angioedema in the emergency department
25 May, 2017 | 14:46h | UTCAngioedema in the emergency department: a practical guide to differential diagnosis and management – International Journal of Emergency Medicine (free) (RT @Gas_Craic see Tweet)