Daily Archives: April 3, 2017
Building Next Generation Immunization Supply Chains
3 Apr, 2017 | 19:26h | UTCBuilding Next Generation Immunization Supply Chains – Vaccine Supplement (free)
News release: Global Immunization Impact Constrained by Outdated Vaccine Delivery Systems, Researchers Say – World Health Organization(free)
See also: Battling Infectious Diseases in the 20th Century: The Impact of Vaccines (free – classic 2015 page with interesting infographics) (RT @stefaniei)
This 29 open access articles are part of a special supplement published in Vaccine to address the challenges of Immunization Supply Chains.
The World Is Unprepared for a Global Pandemic
3 Apr, 2017 | 19:22h | UTCThe World Is Completely Unprepared for a Global Pandemic – Harvard Business Review (free) (RT @glassmanamanda and @BillGates)
Return on investment of public health interventions
3 Apr, 2017 | 19:25h | UTCSource: BMJ News ($)
“For every £1 invested in public health, £14 will subsequently be returned to the wider health and social care economy”. Based on the findings, the authors suggest that cuts to public health services are short sighted and represent a false economy, with substantial opportunity costs.
Cognitive Dysfunction in Older Adults With Diabetes
3 Apr, 2017 | 19:18h | UTCCognitive Dysfunction in Older Adults With Diabetes: What a Clinician Needs to Know – Diabetes Care (free)
Source: Management of Older Adults With Diabetes and Cognitive Dysfunction – PracticeUpdate (free registration required)
“Recommendations include the need for simplified medication regimens, avoidance of glucose-lowering drugs with a high risk of hypoglycemia, periodic reassessment of glycemic goals, and repeated education of the patient and caregiver” (from PracticeUpdate commentary above)
Intensive glucose control and microvascular outcomes
3 Apr, 2017 | 19:21h | UTCEffects of intensive glucose control on microvascular outcomes in patients with type 2 diabetes: a meta-analysis of individual participant data from randomised controlled trials – The Lancet Diabetes & Endocrinology (RT @EricTopol see Tweet with interest discussion) (link to abstract – $ required for full-text)
Contradicting the analysis above, a recent report found no significant impact of tight glycemic control on the risk of dialysis / transplantation / renal death, blindness, or neuropathy: Glycemic Control for Patients With Type 2 Diabetes Mellitus: Our Evolving Faith in the Face of Evidence – Circulation (free)
Benefits of intensive glucose control on microvascular outcomes in patients with type 2 diabetes remains controversial.
Neuropathic pain in adults
3 Apr, 2017 | 19:23h | UTC
Anti-leukotriene agents in persistent asthma
3 Apr, 2017 | 19:15h | UTCAddition of anti-leukotriene agents to inhaled corticosteroids for adults and adolescents with persistent asthma – Cochrane Database of Systematic Reviews (link to summary – $ required for full-text)
Source: EvidenceAlerts
In patients with asthma not controlled with daily low-dose inhaled corticosteroids, adding anti-leukotriene agents reduced by half the number of patients with asthma exacerbations requiring an oral corticosteroid and improved lung function and asthma control.
Functional Hypothalamic Amenorrhea Guideline
3 Apr, 2017 | 19:17h | UTCFunctional Hypothalamic Amenorrhea: An Endocrine Society Clinical Practice Guideline (free PDF)
Source: Endocrine Society Issues Hypothalamic Amenorrhea Guideline – Medscape (free registration required)
Corticosteroids in septic shock
3 Apr, 2017 | 19:12h | UTCCorticosteroids in septic shock: a systematic review and network meta-analysis – Critical Care (free)
Anemia and blood transfusion in the critically ill patient with cardiovascular disease
3 Apr, 2017 | 19:14h | UTC
Mon, Apr 3 – Top 10 Medical News Stories
3 Apr, 2017 | 00:18h | UTC
1 – Building Next Generation Immunization Supply Chains – Vaccine Supplement (free)
News release: Global Immunization Impact Constrained by Outdated Vaccine Delivery Systems, Researchers Say – World Health Organization (free)
See also: Battling Infectious Diseases in the 20th Century: The Impact of Vaccines (free – classic 2015 page with interesting infographics) (RT @stefaniei)
This 29 open access articles are part of a special supplement published in Vaccine to address the challenges of Immunization Supply Chains.
Source: BMJ News ($)
“For every £1 invested in public health, £14 will subsequently be returned to the wider health and social care economy”. Based on the findings, the authors suggest that cuts to public health services are short sighted and represent a false economy, with substantial opportunity costs.
4 – The World Is Completely Unprepared for a Global Pandemic – Harvard Business Review (free) (RT @glassmanamanda and @BillGates)
5 – Effects of intensive glucose control on microvascular outcomes in patients with type 2 diabetes: a meta-analysis of individual participant data from randomised controlled trials – The Lancet Diabetes & Endocrinology (RT @EricTopol see Tweet with interest discussion) (link to abstract – $ required for full-text)
Contradicting the analysis above, a recent report found no significant impact of tight glycemic control on the risk of dialysis / transplantation / renal death, blindness, or neuropathy: Glycemic Control for Patients With Type 2 Diabetes Mellitus: Our Evolving Faith in the Face of Evidence – Circulation (free)
Benefits of intensive glucose control on microvascular outcomes in patients with type 2 diabetes remains controversial.
Source: Management of Older Adults With Diabetes and Cognitive Dysfunction – PracticeUpdate (free registration required)
“Recommendations include the need for simplified medication regimens, avoidance of glucose-lowering drugs with a high risk of hypoglycemia, periodic reassessment of glycemic goals, and repeated education of the patient and caregiver” (from PracticeUpdate commentary above)
7 – Functional Hypothalamic Amenorrhea: An Endocrine Society Clinical Practice Guideline (free PDF)
Source: Endocrine Society Issues Hypothalamic Amenorrhea Guideline – Medscape (free registration required)
8 – Addition of anti-leukotriene agents to inhaled corticosteroids for adults and adolescents with persistent asthma – Cochrane Database of Systematic Reviews (link to summary – $ required for full-text)
Source: EvidenceAlerts
In patients with asthma not controlled with daily low-dose inhaled corticosteroids, adding anti-leukotriene agents reduced by half the number of patients with asthma exacerbations requiring an oral corticosteroid and improved lung function and asthma control.
10 – Corticosteroids in septic shock: a systematic review and network meta-analysis – Critical Care (free)